Antioxidant and immunomodulatory activities of Chinese tonifying herbs

Pharmaceutical Biology

Volumn 40, Issue 5, 2002, Pages 329-335

  Yim, T K ^a   Ko, K M ^a   Ko, Robert ^a  

^a HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

Antioxidation; Chinese herb; Free radical; Glutathione; Immunomodulation; Mouse splenocyte

Indexed keywords

ANGELICA SINENSIS EXTRACT; ASPARAGUS COCHINCHINENSIS EXTRACT; ASTRAGALUS MEMBRANACEUS EXTRACT; ATRACTYLODES MACROCEPHALA EXTRACT; CODONOPSIS PILOSULA EXTRACT; DENDROBIUM NOBILE EXTRACT; DIOSCOREA OPPOSITA EXTRACT; DOLICHOS LABLAB EXTRACT; ECLIPTA PROSTRATA EXTRACT; EUCOMMIA ULMOIDES EXTRACT; FICUS SIMPLICISSIMA EXTRACT; GINSENG EXTRACT; GLYCYRRHIZA URALENSIS EXTRACT; LIGUSTRUM LUCIDUM EXTRACT; LYCIUM CHINENSE EXTRACT; METHANOL; MORUS ALBA EXTRACT; OPHIOPOGON JAPONICUM EXTRACT; ORYZA SATIVA EXTRACT; PANAX QUINQUEFOLIUS EXTRACT; PLANT EXTRACT; POLYGONATUM SIBIRICUM EXTRACT; POLYGONUM MULTIFLORUM EXTRACT; PRINSEPIA UNIFLORA EXTRACT; PSEUDOSTELLARIA HETEROPHYLLA EXTRACT; PSORALEA CORYLIFOLIA EXTRACT; REHMANNIA GLUTINOSA EXTRACT; SESAMUM INDICUM EXTRACT; UNCLASSIFIED DRUG; UNINDEXED DRUG; ZIZIPHUS JUJUBA EXTRACT;

ANGELICA SINENSIS; ANTIOXIDANT ACTIVITY; ARTICLE; ASPARAGUS COCHINCHINENSIS; ASTRAGALUS MEMBRANACEUS; ATRACTYLODES MACROCEPHALA; CHINESE HERB; CODONOPSIS PILOSULA; DENDROBIUM NOBILE; DIOSCOREA OPPOSITA; DOLICHOS LABLAB; DRUG ISOLATION; ECLIPTA PROSTRATA; FICUS SIMPLICISSIMA; GINSENG; GLYCYRRHIZA URALENSIS; IMMUNOMODULATION; IMMUNOSTIMULATION; IMMUNOSUPPRESSIVE TREATMENT; LIGUSTRUM LUCIDUM; LIVER REGENERATION; LYCIUM CHINENSE; OPHIOPOGON JAPONICUS; PANAX QUINQUEFOLIUS; POLYGONATUM ODORATUM; POLYGONATUM SIBIRICUM; POLYGONUM MULTIFLORUM; PRINSEPIA UNIFLORA; PSEUDOSTELLARIA HETEROPHYLLA; PSORALEA CORYLIFOLIA; REHMANIA GLUTINOSA; RICE; SESAME; SPLEEN CELL; TU CHUNG; ZIZIPHUS JUJUBA;

ANGELICA SINENSIS; ASPARAGUS; ASPARAGUS COCHINCHINENSIS; ASTRAGALUS MEMBRANACEUS; ATRACTYLODES; ATRACTYLODES MACROCEPHALA; CODONOPSIS; CODONOPSIS PILOSULA; CULLEN CORYLIFOLIA; DENDROBIUM; DENDROBIUM NOBILE; DIOSCOREA; DIOSCOREA OPPOSITIFOLIA; DOLICHOS; ECLIPTA PROSTRATA; EUCOMMIA ULMOIDES; GLYCYRRHIZA; GLYCYRRHIZA URALENSIS; LABLAB PURPUREUS; LIGUSTRUM; LIGUSTRUM LUCIDUM; LYCIUM; LYCIUM CHINENSE; MORUS ALBA; OPHIOPOGON; OPHIOPOGON JAPONICUS; ORYZA SATIVA; PANAX; PANAX GINSENG; PANAX QUINQUEFOLIUS; POLYGONATUM; POLYGONATUM ODORATUM; POLYGONUM; PRINSEPIA; PRINSEPIA UNIFLORA; PSEUDOSTELLARIA; PSORALEA; REHMANNIA GLUTINOSA; SESAMUM; SESAMUM INDICUM; ZIZIPHUS;

EID: 0038723635     PISSN: 13880209     EISSN: None     Source Type: Journal    
DOI: 10.1076/phbi.40.5.329.8457     Document Type: Article

References (24)

1. Ames BN, Shigenaga MK, Hagen TM (1993): Oxidants, antioxidants, and the degenerative diseases of aging. Proc Natl Acad Sci USA 90: 7915-7922.
2. Bendich A (1993): Physiological role of antioxidants in the immune system. J Dairy Sci 76: 2789-2794.
3. Cheng YH, Shen TF, Pang VF, Chen BJ (2001): Effects of aflatoxin and carotenoids on growth performance and immune response in mule ducklings. Comp Biochem Physiol 128: 19-26.
4. De la Fuente M, Ferrandez MD, Del Rio M, Sol Burgos M, Miquel J (1998): Enhancement of leukocyte functions in aged mice supplemented with the antioxidant thioproline. Mech Aging Dev 104: 213-225.
5. Del Rio M, Ruedas G, Medina S, Victor VM, De la Fuente M (1998): Improvement by several antioxidants of macrophage function in vitro. Life Sci 63: 871-881.
6. Doria G, Frasca D, Adorini L (1983): Immunoregulation of antibody response in aging. In: Yamamura Y, Tada T, eds., Progress in Immunology V. Tokyo, Academic Press, pp. 1549-1561.
7. Geng J, Huang W, Ren T, Ma X (1991): Practical Traditional Chinese Medicine & Pharmacology. Beijing, New World Press, pp. 208-234.
8. Harman D (1994): Free-radical theory of aging, increasing the functional life span. Ann NY Acad Sci 717: 1-15.
9. Hatano T, Edamatsu R, Hiramatsu M, Mori A, Fujita Y, Yasuhara T, Yoshida T, Okuda T (1989): Effects of the interactions of tannins with co-existing substances. VI. Effects of tannins and related polyphenols on superoxide anion radical, and on 1,1-diphenyl-2-picrylhydrazyl radical. Chem Pharm Bull 37: 2016-2021.
10. Heidrick ML, Hendricks LC, Cook DE (1984): Effect of dietary 2-mercaptoethanol on the life span, immune system, tumor incidence and lipid peroxidation damage in spleen lymphocytes of aging BC3F1 mice. Mech Aging Dev 27: 341-358.
11. Hirano T, Oka K, Kawashima E, Akiba M (1989): Effects of synthetic and naturally occurring flavonoids on mitogen-induced proliferation of human peripheral-blood lymphocytes. Life Sci 45: 1407-1411.
12. Hughes DA (1999): Effects of carotenoids on human immune functions. Proc Nutr Soc 58: 713-718.
13. Ko KM, Mak DHF, Li PC, Poon MKT, Ip SP (1995a): Enhancement of hepatic glutathione regeneration capacity by a lignan-enriched extract of Fructus schisandrae in rats. Jpn J Pharmacol 69: 439-442.
14. Ko KM, Ip SP, Poon MKT, Wu SS, Che CT, Ng KH, Kong YC (1995b): Effect of a lignan-enriched Fructus schisandrae extract on hepatic glutathione status in rats: Protection against carbon tetrachloride toxicity. Planta Med 61: 134-137.
15. Ko KM, Mak DHF, Li PC, Poon MKT, Ip SP (1996): Protective effect of a lignan-enriched extract of Fructus schisandrae on physical exercise induced muscle damage in rats. Phytother Res 10: 450-452.
16. Lin CC, Hsu YF, Lin TC (2001): Antioxidant and free radical scavenging effects of the tannins of Terminalia catappa L. Anticancer Res 21: 237-243.
17. Martin KR, Failla ML, Smith JC Jr (1996): Beta-carotene and lutein protect HepG2 human liver cells against oxidant-induced damage. J Nutr 126: 2098-2106.
18. Middleton E (1998): Effect of plant flavonoids on immune and inflammatory cell function. Adv Exp Med Biol 439: 175-182.
19. Miller RA (1991): Aging and immune function. Int Rev Cytol 124: 187-215.
20. Namgoong SY, Son KH, Chang HW, Kang SS, Kim HP (1994): Effects of naturally occurring flavonoids on mitogen-induced lymphocyte proliferation and mixed lymphocyte culture. Life Sci 54: 313-320.
21. Rodriguez RJ, Miranda CL, Stevens JF, Deinzer ML, Buhler DR (2001): Influence of prenylated and non-prenylated flavonoids on liver microsomal lipid peroxidation and oxidative injury in rat hepatocytes. Food Chem Toxicol 39: 437-445.
22. Serafini M, Maiani G, Ferro-Luzzi A (1996): In vitro antioxidant effect of green and black tea in man. Eur J Clin Nutr 50: 28-32.
23. Yim TK, Ko KM (2001): Effects of Fructus Ligustri lucidi extracts on concanavalin A-stimulated proliferation of isolated murine splenocytes. Pharm Biol 39: 146-151.
24. Yim TK, Wu WK, Mak DHF, Ko KM (1998): Myocardial protective effect of an anthraquinone-containing extract of Polygonum multiflorum ex vivo. Planta Med 64: 607-611.