메뉴 건너뛰기




Volumn 5, Issue SUPPL. 1, 2003, Pages

The ideal pharmacokinetic properties of an antiepileptic drug: How close does levetiracetam come?

Author keywords

Antiepileptic drugs; Drug interactions; Levetiracetam; Pharmacokinetics; Review

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; ETIRACETAM; FELBAMATE; GABAPENTIN; LAMOTRIGINE; OXCARBAZEPINE; PHENOBARBITAL; PHENYTOIN; PLASMA PROTEIN; PRIMIDONE; TIAGABINE; TOPIRAMATE; VALPROIC ACID; VIGABATRIN; ZONISAMIDE;

EID: 0038722225     PISSN: 12949361     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (69)

References (55)
  • 1
    • 0003902219 scopus 로고    scopus 로고
    • Pharmacokinetics
    • Engel J Jr, Pedley TA. New York: Raven Press
    • Perucca E. Pharmacokinetics. In: Engel J Jr, Pedley TA. Epilepsy - A Comprehensive Textbook. New York: Raven Press, 1997: 1131-53.
    • (1997) Epilepsy - A Comprehensive Textbook , pp. 1131-1153
    • Perucca, E.1
  • 2
    • 0030485569 scopus 로고    scopus 로고
    • Established antiepileptic drugs
    • Brodie MJ, Treiman DM. Baillère's Clinical Neurology, London: Baillière-Tindall
    • Perucca E. Established antiepileptic drugs. In: Brodie MJ, Treiman DM. Modern Management of Epilepsy. Baillère's Clinical Neurology, vol 5. London: Baillière-Tindall, 1996: 693-722.
    • (1996) Modern Management of Epilepsy , vol.5 , pp. 693-722
    • Perucca, E.1
  • 3
    • 72849166751 scopus 로고
    • Clinical and electroencephalographic correlations of serum levels of diphenylhydantoin
    • Buchtal F, Svensmark O, Schiller PJ. Clinical and electroencephalographic correlations of serum levels of diphenylhydantoin. Arch Neurol 1960; 2: 624-30.
    • (1960) Arch Neurol , vol.2 , pp. 624-630
    • Buchtal, F.1    Svensmark, O.2    Schiller, P.J.3
  • 4
    • 0016261305 scopus 로고
    • Anticonvulsant effect of diphenylhydantoin relative to plasma levels. A prospective three-year study in ambulant patients with generalized epileptic seizures
    • Lund L. Anticonvulsant effect of diphenylhydantoin relative to plasma levels. A prospective three-year study in ambulant patients with generalized epileptic seizures. Arch Neurol 1974; 31: 289-94.
    • (1974) Arch Neurol , vol.31 , pp. 289-294
    • Lund, L.1
  • 5
    • 0017281981 scopus 로고
    • The relation of anticonvulsant drug levels to complete seizure control
    • Feldman RG, Pippenger CE. The relation of anticonvulsant drug levels to complete seizure control. J Clin Pharmacol 1976; 16: 51-59.
    • (1976) J Clin Pharmacol , vol.16 , pp. 51-59
    • Feldman, R.G.1    Pippenger, C.E.2
  • 6
    • 0029826744 scopus 로고    scopus 로고
    • The new generation of antiepileptic drugs: Advantages and disadvantages
    • Perucca E. The new generation of antiepileptic drugs: advantages and disadvantages. Br J Clin Pharmacol 1996; 42: 531-43.
    • (1996) Br J Clin Pharmacol , vol.42 , pp. 531-543
    • Perucca, E.1
  • 7
    • 0034091545 scopus 로고    scopus 로고
    • The new antiepileptic drugs: Pharmacological and clinical aspects
    • Gatti G, Bonomi I, Jannuzzi G, et al. The new antiepileptic drugs: pharmacological and clinical aspects. Curr Pharm Des 2000; 6: 839-60.
    • (2000) Curr Pharm Des , vol.6 , pp. 839-860
    • Gatti, G.1    Bonomi, I.2    Jannuzzi, G.3
  • 8
    • 0035571150 scopus 로고    scopus 로고
    • The clinical pharmacology and therapeutic use of the new antiepileptic drugs
    • Perucca E. The clinical pharmacology and therapeutic use of the new antiepileptic drugs. Fund Clin Pharmacol 2001; 15: 405-17.
    • (2001) Fund Clin Pharmacol , vol.15 , pp. 405-417
    • Perucca, E.1
  • 9
    • 0027454448 scopus 로고
    • Gabapentin. A review of its pharmacological properties and clinical potential in epilepsy
    • Goa KL, Sorkin EM. Gabapentin. A review of its pharmacological properties and clinical potential in epilepsy. Drugs 1993; 46: 409-27.
    • (1993) Drugs , vol.46 , pp. 409-427
    • Goa, K.L.1    Sorkin, E.M.2
  • 10
    • 0031938906 scopus 로고    scopus 로고
    • Tiagabine. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the management of epilepsy
    • Adkins JC, Noble S. Tiagabine. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the management of epilepsy. Drugs 1998; 55: 437-60.
    • (1998) Drugs , vol.55 , pp. 437-460
    • Adkins, J.C.1    Noble, S.2
  • 11
    • 0032779380 scopus 로고    scopus 로고
    • The clinical pharmacokinetics of the new antiepileptic drugs
    • Perucca E. The clinical pharmacokinetics of the new antiepileptic drugs. Epilepsia 1999; 40(Suppl 9): S7-13.
    • (1999) Epilepsia , vol.40 , Issue.SUPPL. 9
    • Perucca, E.1
  • 12
    • 0002587609 scopus 로고
    • Biotransformation
    • Levy RH, Mattson RH, Meldrum B. New York: Raven Press
    • Perucca E, Richens A. Biotransformation. In: Levy RH, Mattson RH, Meldrum B. Antiepileptic Drugs. New York: Raven Press, 1995: 31-50.
    • (1995) Antiepileptic Drugs , pp. 31-50
    • Perucca, E.1    Richens, A.2
  • 13
    • 0033753984 scopus 로고    scopus 로고
    • Antiepileptic drug interactions
    • French JA, Gidal BE. Antiepileptic drug interactions. Epilepsia 2000; 41 (Suppl 8): S30-6.
    • (2000) Epilepsia , vol.41 , Issue.SUPPL. 8
    • French, J.A.1    Gidal, B.E.2
  • 14
    • 0033621925 scopus 로고    scopus 로고
    • Pharmacokinetic profile of levetiracetam: Toward ideal characteristics
    • Patsalos PN. Pharmacokinetic profile of levetiracetam: toward ideal characteristics. Pharmacol Ther 2000; 85: 77-85.
    • (2000) Pharmacol Ther , vol.85 , pp. 77-85
    • Patsalos, P.N.1
  • 15
    • 0034864245 scopus 로고    scopus 로고
    • Pharmacokinetics of levetiracetam
    • Radtke RA. Pharmacokinetics of levetiracetam. Epilepsia 2001; 42(Suppl 4): 24-7.
    • (2001) Epilepsia , vol.42 , Issue.SUPPL. 4 , pp. 24-27
    • Radtke, R.A.1
  • 16
    • 0034892646 scopus 로고    scopus 로고
    • A microdialysis study of the novel antiepileptic drug levetiracetam: Extracellular pharmacokinetics and effect on taurine in rat brain
    • Tong X, Patsalos PN. A microdialysis study of the novel antiepileptic drug levetiracetam: extracellular pharmacokinetics and effect on taurine in rat brain. Br J Pharmacol 2001; 133: 867-74.
    • (2001) Br J Pharmacol , vol.133 , pp. 867-874
    • Tong, X.1    Patsalos, P.N.2
  • 17
    • 0034849129 scopus 로고    scopus 로고
    • Pharmacokinetics of levetiracetam and its enantiomer (R)-alpha-ethyl-2-oxo-pyrrolidine acetamide in dogs
    • Isoherranen N, Yagen B, Soback S, et al. Pharmacokinetics of levetiracetam and its enantiomer (R)-alpha-ethyl-2-oxo-pyrrolidine acetamide in dogs. Epilepsia 2001; 42: 825-30.
    • (2001) Epilepsia , vol.42 , pp. 825-830
    • Isoherranen, N.1    Yagen, B.2    Soback, S.3
  • 18
    • 0033756611 scopus 로고    scopus 로고
    • Levetiracetam. A review of its adjunctive use in the management of partial onset seizures
    • Dooley M, Plosker GL. Levetiracetam. A review of its adjunctive use in the management of partial onset seizures. Drugs 2000; 60: 871-93.
    • (2000) Drugs , vol.60 , pp. 871-893
    • Dooley, M.1    Plosker, G.L.2
  • 19
    • 0035675738 scopus 로고    scopus 로고
    • Pharmacokinetic study of levetiracetam in children
    • Pellock JM, Glauser TA, Bebin EM, et al. Pharmacokinetic study of levetiracetam in children. Epilepsia 2001; 42: 1574-9.
    • (2001) Epilepsia , vol.42 , pp. 1574-1579
    • Pellock, J.M.1    Glauser, T.A.2    Bebin, E.M.3
  • 20
    • 0034876919 scopus 로고    scopus 로고
    • Use of levetiracetam in special populations
    • French J. Use of levetiracetam in special populations. Epilepsia 2001; 42 (Suppl 4): 40-3.
    • (2001) Epilepsia , vol.42 , Issue.SUPPL. 4 , pp. 40-43
    • French, J.1
  • 21
    • 0032963256 scopus 로고    scopus 로고
    • In vitro evaluation of potential drug interactions with levetiracetam, a new antiepileptic agent
    • Nicolas JM, Collart P, Gerin B, et al. In vitro evaluation of potential drug interactions with levetiracetam, a new antiepileptic agent. Drug Metab Dispos 1999; 27: 250-4.
    • (1999) Drug Metab Dispos , vol.27 , pp. 250-254
    • Nicolas, J.M.1    Collart, P.2    Gerin, B.3
  • 22
    • 0002491407 scopus 로고    scopus 로고
    • Levetiracetam does not interact with other antiepileptic drugs
    • Perucca E, Gidal BE, Ledent E, et al. Levetiracetam does not interact with other antiepileptic drugs. Epilepsia 2000; 41 (Suppl 7): 254-5.
    • (2000) Epilepsia , vol.41 , Issue.SUPPL. 7 , pp. 254-255
    • Perucca, E.1    Gidal, B.E.2    Ledent, E.3
  • 23
    • 0033663648 scopus 로고    scopus 로고
    • Absence of pharmacokinetic drug interaction of levetiracetam with phenytoin in patients with epilepsy determined by new technique
    • Browne TR, Szabo GK, Leppik IE, et al. Absence of pharmacokinetic drug interaction of levetiracetam with phenytoin in patients with epilepsy determined by new technique. J Clin Pharmacol 2000; 40: 590-5.
    • (2000) J Clin Pharmacol , vol.40 , pp. 590-595
    • Browne, T.R.1    Szabo, G.K.2    Leppik, I.E.3
  • 24
    • 0002800735 scopus 로고    scopus 로고
    • Influence of a new antiepileptic drug (levetiracetam. Ucb L059) on the pharmacokinetics and pharmacodynamics of oral contraceptives
    • Giuliano RA, Hiersemenzel R, Baltes E, et al. Influence of a new antiepileptic drug (levetiracetam. Ucb L059) on the pharmacokinetics and pharmacodynamics of oral contraceptives. Epilepsia 1996; 37 (Suppl 4): 90.
    • (1996) Epilepsia , vol.37 , Issue.SUPPL. 4 , pp. 90
    • Giuliano, R.A.1    Hiersemenzel, R.2    Baltes, E.3
  • 25
    • 0034900762 scopus 로고    scopus 로고
    • Repeated administration of the novel antiepileptic agent levetiracetam does not alter digoxin pharmacokinetics and pharmacodynamics in healthy volunteers
    • Levy RH, Ragueneau-Majlessi I, Baltes E. Repeated administration of the novel antiepileptic agent levetiracetam does not alter digoxin pharmacokinetics and pharmacodynamics in healthy volunteers. Epilepsy Res 2001; 46: 93-9.
    • (2001) Epilepsy Res , vol.46 , pp. 93-99
    • Levy, R.H.1    Ragueneau-Majlessi, I.2    Baltes, E.3
  • 26
    • 0034757376 scopus 로고    scopus 로고
    • Lack of effect of repeated administration of levetiracetam on the pharmacodynamic and pharmacokinetic profiles of warfarin
    • Ragueneau-Majlessi I, Levy RH, Meyerhoff C. Lack of effect of repeated administration of levetiracetam on the pharmacodynamic and pharmacokinetic profiles of warfarin. Epilepsy Res 2001; 47: 55-63.
    • (2001) Epilepsy Res , vol.47 , pp. 55-63
    • Ragueneau-Majlessi, I.1    Levy, R.H.2    Meyerhoff, C.3
  • 27
    • 0027323538 scopus 로고
    • Felbamate: A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in epilepsy
    • Palmer KJ, McTavish D. Felbamate: A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in epilepsy. Drugs 1993; 45: 1041-65.
    • (1993) Drugs , vol.45 , pp. 1041-1065
    • Palmer, K.J.1    McTavish, D.2
  • 30
    • 0030748999 scopus 로고    scopus 로고
    • Pharmacokinetic interactions with felbamate. In vitro-in vivo correlation
    • Glue P, Banfield CR, Perhach JL, et al. Pharmacokinetic interactions with felbamate. In vitro-in vivo correlation. Clin Pharmacokinet 1997; 33: 214-24.
    • (1997) Clin Pharmacokinet , vol.33 , pp. 214-224
    • Glue, P.1    Banfield, C.R.2    Perhach, J.L.3
  • 31
    • 0027179598 scopus 로고
    • Lamotrigine. A review of its pharmacological properties and clinical efficacy in epilepsy
    • Goa KL, Ross SR, Chrisp P. Lamotrigine. A review of its pharmacological properties and clinical efficacy in epilepsy. Drugs 1993; 46: 152-76.
    • (1993) Drugs , vol.46 , pp. 152-176
    • Goa, K.L.1    Ross, S.R.2    Chrisp, P.3
  • 32
    • 0029125093 scopus 로고
    • Lamotrigine. An update of its pharmacology and therapeutic use in epilepsy
    • Fitton A, Goa KL. Lamotrigine. An update of its pharmacology and therapeutic use in epilepsy. Drugs 1995; 50: 691-713.
    • (1995) Drugs , vol.50 , pp. 691-713
    • Fitton, A.1    Goa, K.L.2
  • 33
    • 0031450994 scopus 로고    scopus 로고
    • The influence of dosage, age and comedication on steady state plasma lamotrigine concentrations in epileptic children: A prospective study with preliminary assessment of correlations with clinical response
    • Bartoli A, Guerrini R, Belmonte A, et al. The influence of dosage, age and comedication on steady state plasma lamotrigine concentrations in epileptic children: a prospective study with preliminary assessment of correlations with clinical response. Ther Drug Monit 1997; 19: 252-60.
    • (1997) Ther Drug Monit , vol.19 , pp. 252-260
    • Bartoli, A.1    Guerrini, R.2    Belmonte, A.3
  • 34
    • 0034041253 scopus 로고    scopus 로고
    • Lamotrigine in pregnancy: Pharmacokinetics during delivery, in the neonate, and during lactation
    • Ohman I, Vitols S, Tomson T. Lamotrigine in pregnancy: pharmacokinetics during delivery, in the neonate, and during lactation. Epilepsia 2000; 41: 709-13.
    • (2000) Epilepsia , vol.41 , pp. 709-713
    • Ohman, I.1    Vitols, S.2    Tomson, T.3
  • 35
    • 0034856932 scopus 로고    scopus 로고
    • Influence of cirrhosis on lamotrigine pharmacokinetics
    • Marcellin P, de Bony F, Garret C, et al. Influence of cirrhosis on lamotrigine pharmacokinetics. Br J Clin Pharmacol 2001; 51: 410-4.
    • (2001) Br J Clin Pharmacol , vol.51 , pp. 410-414
    • Marcellin, P.1    De Bony, F.2    Garret, C.3
  • 36
    • 0023574269 scopus 로고
    • Lamotrigine: Single-dose pharmacokinetics and initial 1 week experience in refractory epilepsy
    • Jawad S, Yuen WC, Peck AW, et al. Lamotrigine: single-dose pharmacokinetics and initial 1 week experience in refractory epilepsy. Epilepsy Res 1987; 1: 194-210.
    • (1987) Epilepsy Res , vol.1 , pp. 194-210
    • Jawad, S.1    Yuen, W.C.2    Peck, A.W.3
  • 37
    • 0034779805 scopus 로고    scopus 로고
    • Lamotrigine plasma levels reduced by oral contraceptives
    • Sabers A, Buchholt JM, Uldall P, et al. Lamotrigine plasma levels reduced by oral contraceptives. Epilepsy Res 2001; 47: 151-4.
    • (2001) Epilepsy Res , vol.47 , pp. 151-154
    • Sabers, A.1    Buchholt, J.M.2    Uldall, P.3
  • 38
    • 0032799794 scopus 로고    scopus 로고
    • The efficacy of valproate-lamotrigine comedication in refractory complex partial seizures: Evidence for a pharmacodynamic interaction
    • Pisani F, Oteri G, Russo MF, et al. The efficacy of valproate-lamotrigine comedication in refractory complex partial seizures: evidence for a pharmacodynamic interaction. Epilepsia 1999; 40: 1141-6.
    • (1999) Epilepsia , vol.40 , pp. 1141-1146
    • Pisani, F.1    Oteri, G.2    Russo, M.F.3
  • 39
    • 0026721245 scopus 로고
    • Oxcarbazepine. A review of its pharmacology and therapeutic potential in epilepsy, trigeminal neuralgia and affective disorders
    • Grants SM, Faulds D. Oxcarbazepine. A review of its pharmacology and therapeutic potential in epilepsy, trigeminal neuralgia and affective disorders. Drugs 1992; 43: 873-88.
    • (1992) Drugs , vol.43 , pp. 873-888
    • Grants, S.M.1    Faulds, D.2
  • 40
    • 0035097209 scopus 로고    scopus 로고
    • Oxcarbazepine: An update of its efficacy in the management of epilepsy
    • Wellington K, Goa KL. Oxcarbazepine: an update of its efficacy in the management of epilepsy. CNS Drugs 2001; 15: 137-63.
    • (2001) CNS Drugs , vol.15 , pp. 137-163
    • Wellington, K.1    Goa, K.L.2
  • 41
    • 0027939494 scopus 로고
    • The effect of renal impairment on the pharmacokinetics of oxcarbazepine and its metabolites
    • Rouan MC, Lecaillon JB, Godbillon J, et al. The effect of renal impairment on the pharmacokinetics of oxcarbazepine and its metabolites. Eur J Clin Pharmacol 1994; 47: 161-7.
    • (1994) Eur J Clin Pharmacol , vol.47 , pp. 161-167
    • Rouan, M.C.1    Lecaillon, J.B.2    Godbillon, J.3
  • 42
    • 0033052684 scopus 로고    scopus 로고
    • Induction of ethinylestradiol and levonorgestrel metabolism by oxcarbazepine in healthy women
    • Fattore C, Cipolla G, Gatti G, et al. Induction of ethinylestradiol and levonorgestrel metabolism by oxcarbazepine in healthy women. Epilepsia 1999; 40: 783-7.
    • (1999) Epilepsia , vol.40 , pp. 783-787
    • Fattore, C.1    Cipolla, G.2    Gatti, G.3
  • 43
    • 0030960662 scopus 로고    scopus 로고
    • A single-dose study to define tiagabine pharmacokinetics in pediatric patients with complex partial seizures
    • Gustavson LE, Boellner SW, Granneman GR, et al. A single-dose study to define tiagabine pharmacokinetics in pediatric patients with complex partial seizures. Neurology 1997; 48: 1032-7.
    • (1997) Neurology , vol.48 , pp. 1032-1037
    • Gustavson, L.E.1    Boellner, S.W.2    Granneman, G.R.3
  • 44
    • 0030944488 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of tiagabine in subjects with various degrees of hepatic function
    • Lau AH, Gustavson LE, Sperelakis R, et al. Pharmacokinetics and safety of tiagabine in subjects with various degrees of hepatic function. Epilepsia 1997; 38: 445-51.
    • (1997) Epilepsia , vol.38 , pp. 445-451
    • Lau, A.H.1    Gustavson, L.E.2    Sperelakis, R.3
  • 45
    • 0029887507 scopus 로고    scopus 로고
    • The pharmacokinetics of the newer antiepileptic drugs. Focus on topiramate, zonisamide and tiagabine
    • Perucca E, Bialer M. The pharmacokinetics of the newer antiepileptic drugs. Focus on topiramate, zonisamide and tiagabine. Clin Pharmacokinet 1996; 31: 29-46.
    • (1996) Clin Pharmacokinet , vol.31 , pp. 29-46
    • Perucca, E.1    Bialer, M.2
  • 46
    • 0034308127 scopus 로고    scopus 로고
    • Tiagabine in the treatment of epilepsy - A clinical review with a guide for the prescribing physician
    • Schmidt D, Gram L, Brodie M, et al. Tiagabine in the treatment of epilepsy - a clinical review with a guide for the prescribing physician. Epilepsy Res 2000; 41: 245-51.
    • (2000) Epilepsy Res , vol.41 , pp. 245-251
    • Schmidt, D.1    Gram, L.2    Brodie, M.3
  • 47
    • 0029897629 scopus 로고    scopus 로고
    • Pharmacokinetic profile of topiramate in comparison with other new antiepileptic drugs
    • Perucca E. Pharmacokinetic profile of topiramate in comparison with other new antiepileptic drugs. Epilepsia 1996; 37 (Suppl 2): S8-13.
    • (1996) Epilepsia , vol.37 , Issue.SUPPL. 2
    • Perucca, E.1
  • 48
    • 0030710582 scopus 로고    scopus 로고
    • Topiramate. A review of its pharmacodynamic and pharmacokinetic properties and clinical efficacy in the management of epilepsy
    • Langtry HD, Gillis JC, Davis R. Topiramate. A review of its pharmacodynamic and pharmacokinetic properties and clinical efficacy in the management of epilepsy. Drugs 1997; 54: 752-73.
    • (1997) Drugs , vol.54 , pp. 752-773
    • Langtry, H.D.1    Gillis, J.C.2    Davis, R.3
  • 49
    • 0025788909 scopus 로고
    • Vigabatrin. A review of its pharmacokinetic properties, and therapeutic potential in epilepsy and disorders of motor control
    • Grant SM, Heel RC. Vigabatrin. A review of its pharmacokinetic properties, and therapeutic potential in epilepsy and disorders of motor control. Drugs 1991; 41: 889-926.
    • (1991) Drugs , vol.41 , pp. 889-926
    • Grant, S.M.1    Heel, R.C.2
  • 50
    • 0026674193 scopus 로고
    • Vigabatrin. Clinical pharmacokinetics
    • Rey E, Pons G, Olive G. Vigabatrin. Clinical pharmacokinetics. Clin Pharmacokinet 1992; 23: 267-78.
    • (1992) Clin Pharmacokinet , vol.23 , pp. 267-278
    • Rey, E.1    Pons, G.2    Olive, G.3
  • 51
    • 0027131539 scopus 로고
    • Vigabatrin-induced decrease in serum phenytoin concentration does not involve a change in phenytoin bioavailability
    • Gatti G, Bartoli A, Marchiselli R, et al. Vigabatrin-induced decrease in serum phenytoin concentration does not involve a change in phenytoin bioavailability. Br J Clin Pharmacol 1993; 36: 603-6.
    • (1993) Br J Clin Pharmacol , vol.36 , pp. 603-606
    • Gatti, G.1    Bartoli, A.2    Marchiselli, R.3
  • 52
    • 0027314348 scopus 로고
    • Zonisamide. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in epilepsy
    • Peters DH, Sorkin EM. Zonisamide. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in epilepsy. Drugs 1993; 45: 760-87.
    • (1993) Drugs , vol.45 , pp. 760-787
    • Peters, D.H.1    Sorkin, E.M.2
  • 53
    • 0030297525 scopus 로고    scopus 로고
    • Photosensitive epilepsy: A model to study the effects of antiepileptic drugs. Evaluation of the piracetam analogue, levetiracetam
    • Kasteleijn-Nolst Trenité DG, Marescaux C, Stodieck S, et al. Photosensitive epilepsy: a model to study the effects of antiepileptic drugs. Evaluation of the piracetam analogue, levetiracetam. Epilepsy Res 1996; 25: 225-30.
    • (1996) Epilepsy Res , vol.25 , pp. 225-230
    • Kasteleijn-Nolst Trenité, D.G.1    Marescaux, C.2    Stodieck, S.3
  • 54
    • 0034100739 scopus 로고    scopus 로고
    • Is there a role for therapeutic drug monitoring of new anticonvulsants?
    • Perucca E. Is there a role for therapeutic drug monitoring of new anticonvulsants? Clin Pharmacokinet 2000; 38: 191-204.
    • (2000) Clin Pharmacokinet , vol.38 , pp. 191-204
    • Perucca, E.1
  • 55
    • 0033963848 scopus 로고    scopus 로고
    • Therapeutic monitoring of the new antiepileptic drugs
    • Tomson T, Johannessen SI. Therapeutic monitoring of the new antiepileptic drugs. Eur J Clin Pharmacol 2000; 55: 697-705.
    • (2000) Eur J Clin Pharmacol , vol.55 , pp. 697-705
    • Tomson, T.1    Johannessen, S.I.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.