Decrease of ethanol intake following repeated injection of serotonin - 1A agonist in rats: Relationship with receptor responsiveness

Journal of the College of Physicians and Surgeons Pakistan

Volumn 13, Issue 6, 2003, Pages 305-308

  Hasnat, Ambreen ^a   Haider, Saida ^a   Perveen, Tahira ^a   Kidwai, I M ^a   Haleem, Darakhshan Jabeen ^a  

^a UNIVERSITY OF KARACHI   (Pakistan)

Author keywords

5 HT 1A receptors; 8 OH DPAT serotonin; Ethanol; Feedback mechanism

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; ALCOHOL; POSTSYNAPTIC RECEPTOR; PRESYNAPTIC RECEPTOR; SEROTONIN 1A AGONIST;

ALCOHOL CONSUMPTION; ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRINKING BEHAVIOR; DRUG BRAIN LEVEL; DRUG EFFECT; MALE; NEGATIVE FEEDBACK; NONHUMAN; RAT; SEROTONINERGIC SYSTEM;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ALCOHOL DRINKING; ANIMALS; ETHANOL; FEEDBACK, BIOCHEMICAL; MALE; MODELS, ANIMAL; RATS; RATS, WISTAR; RECEPTORS, SEROTONIN; SEROTONIN AGONISTS;

EID: 0038719982     PISSN: 1022386X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Klem WR. Membrane glycoconjugate potential mediators of alcohol effects. Prog Neuropsychopharmacol Biol Psychiatry 1987; 11: 633-58.
2. Tobakoff B, Hoffman PL. Biochemical pharmacology of alcohol. In: Meltzer HY, (edi). Psychopharmacol. The third generation of progress. New York: Raven Press 1987.
3. Bacner N, Kinney TA, Biros M, Bochert S, Casuto N. The relationship among depressive and alcoholic symptoms and aggressive behavior in adult male emergency department patients. Acad Emerg Med 2002; 9: 120-9.
4. Dodig G, Brnabic R, Mrass D, Zuljan-Vvitanovic M, Katavic Z, Loncar C et al. Alcoholism and depression. Coll Antropol 2001; 25:651-5.
5. Cheetam SC, Crompton MR, Katona CI, Horton RW. Brain 5-HT binding sites in depressed suicides. Psychopharmacology 1990; 102:544-8.
6. Haleem DJ. Serotonergic mechanism of antidepressant action and adaptation to stress. J Coll Physicians Surg Pak 1999; 9: 139-46.
7. Badawy AAB, Evans M. The role of free serum tryptophan in the biphasic effect of acute ethanol administration on the concentrations of rat brain tryptophan, 5-HT and 5-HIAA. Biochem J 1976; 160: 315-24.
8. Smith AD, Weiss F. Ethanol exposure differentially alters central monoamine neurotransmission in alcohol-preferring versus-non-preferring rats. J Pharmacol Exp Ther 1999; 288: 1223-8.
9. Katner SN, Weiss F. Neurochemical characteristics associated with ethanol preference in selected alcohol-preferring and non-preferring rats: a quantitative microdialysis study. Alcohol Clin Exp Res 2001; 25: 198-205.
10. McBride WJ, Bodart B, Lumeng L, Li TK. Association between low contents of dopamine and serotonin in the nucleus accumbens and high alcohol preference. Alcohol Clin Exp Res 1995; 19: 1420-2.
11. Haleem DJ. Injected tryptophan increases brain but not plasma tryptophan levels more in ethanol treated rats. Life Sci 1990; 47: 971-9.
12. Haleem DJ, Naz H, Parveen T, Haider S, Ahmed SP, Khan NH, et al. Serotonin and serotonin-1 A receptors in the failure of ethanol treated rats to adapt to a repeated stress schedule. J Stud Alcohol 2002; 63: 389-96.
13. Anisman H, Zacharko RM. Depression: the predisposing influences of depression. Behav Brain Sci 1982; 5: 89-137.
14. Breslau N, Davis GS. Chronic stress and major depression. Arch Gen Psychiatry 1986; 43: 309-14.
15. Brown GW, Bifulco A, Harris TO. Life events, vulnerability and onset of depression: some refinements. Br J Psychiatry 1987; 150:30-42.
16. Cornell DG, Milden RS, Shimp S. Stress life events associated with endogenous depression. J Nerv Ment Dis 1985; 173: 470-6.
17. Berger BD, Adesso VJ. Gender differences in using alcohol to cope with depression. Addict Behav 1991; 16: 315-27.
18. Haleem DJ, Perveen T. Brain regional serotonin synthesis following adaptation to repeated restraint. Neuroreport 1994; 5: 1785-8.
19. Haleem DJ. Adaptation to repeated restraint stress in rats: failure of ethanol treated rats to adapt in the stress schedule. Alcohol Alcohol 1996; 31: 471-7.
20. Haleem DJ. Attenuation of 8-OH-DPAT-induced decreases in 5-HT synthesis in brain regions of rats adapted to a repeated stress schedule. Stress 1999; 3: 123-9.
21. Haleem DJ, Saify ZS, Siddiqui S, Batool F, Haleem MA. Pre and postsynaptic responses to 1-(1-naphthylpiperazine) following adaptation to stress in rats. Prog Neuropsychopharmacol Biol Psychiatry 2002; 26: 149-56.
22. LeMarquand D, Phil RO, Benkelfat C. Serotonin and alcohol intake, abuse and dependence : findings of animal studies. Biol Psychiatry 1994; 36: 395-421,
23. Sellers EM, Higgins GA, Sobell MB. 5-HT and alcohol abuse. Trends Pharmacol Sci 1992; 13: 69-75.
24. Schrieber R, Opitz K, Glaser T, De Vry J. Ipsapirone and 8-OH-DPAT reduce ethanol preference in rats: involvement of presynaptic 5-HT-1 A receptors. Psychopharmacology 1993; 112: 100-10.
25. Svensson L, Engel J, Hard E. Effects of 5-HT receptor agonist, 8-OH-DPAT, on ethanol preference in the rat. Alcohol 1989; 6:17-21.
26. Verge D, Daval G, Patey A, Gozlan H, Mestikawy E, Hamon M. Presynaptic 5-HT autoreceptors on serotonergic cell bodies but not terminals are of the 5-HT-1A type. Eur J Pharmacol 1985; 113: 463-4.
27. Blier P, De Montigney C, Chaupat Y. Modification of the serotonin system by antidepressant treatments: implication for therapeutic response in major depression. J Clin Psychopharmacol 1987; 7:24S-34S.
28. Haleem DJ, Kennett GA, Curzon G. Hippocampal 5-HT synthesis is greater in female rats than in males and is more decreased by 5-HT-1A agonist 8-hydroxy-2-(di-n-propylamino) tetralin. J Neural Transm 1999; 79: 93-101.
29. Hjorth S, Carlsson A, Lindberg P, Sanchez D, Wikstrom H, Arvidsson LE, Hacksell U, Nilsson JLG. 8-hydroxy-2-(di-n-propylamino) tetralin, 8-OH-DPAT, a potent and selective simplified ergot congener with central 5-HT receptor stimulating activity. J Neural Transm 1982; 55: 169-88.
30. Hutson PM, Sarna GS, O'Connell MT, Curzon G. Hippocampal 5-HT synthesis and release is decreased by infusion of 8-OH-DPAT into the raphe nucleus dorsalis. Neurosci Lett 1989; 100: 276-80.
31. Haleem DJ. Sex differences in neurochemical and behavioral effects of 8-hydroxy-2-(di-n-propylamino) tetralin. Life Sci 1992; 50: PL221-6.
32. Tricklebank MD, Forler C, Fozard JR. The involvement of subtypes of 5-HT 1 receptor and of catecholaminergic systems in the behavioral response to 8-hydroxy-2-(di-n-propylamino) tetralin in the rat. Eur J Pharmacol 1984; 106: 271-82.
33. Yamada J, Sugimoto Y, Horisaka K. The behavioral effects of 8-hydroxy-2-(di-n-propylamino) tetralin in mice. Eur J Pharmacol 1988; 154: 299-304.
34. Haleem DJ, Khan NH. Enhancement of serotonin-1A receptor dependent responses following withdrawal of haloperidol in rats. Prog Neuropsychopharmacol Biol Psychiatry 2003; (in press).