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Volumn 119, Issue 12, 1997, Pages 2795-2803

Chemistry of C-2 glyceryl radicals: Indications for a new mechanism of lipid damage

Author keywords

[No Author keywords available]

Indexed keywords

GLYCEROL DERIVATIVE; PHOSPHOLIPID;

EID: 0038716936     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9641416     Document Type: Article
Times cited : (68)

References (37)
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    • For reviews see: (a) Giese, B.; Beyrich-Graf, X.; Erdmann, P.; Petretta, M.; Schwitter, U. Chem. Biol 1995, 2, 367-375. (b) Breen, A. P.; Murphy, J. A. Free Radical Biol. Med. 1995, 18, 1033-1077. (c) Von Sonntag, C.; Hagen, U.; Schön-Bopp, A.; Schulte-Frohlinde, D. Adv. Radical Biol. 1981, 9, 109-142.
    • (1995) Chem. Biol , vol.2 , pp. 367-375
    • Giese, B.1    Beyrich-Graf, X.2    Erdmann, P.3    Petretta, M.4    Schwitter, U.5
  • 4
    • 0028927261 scopus 로고
    • For reviews see: (a) Giese, B.; Beyrich-Graf, X.; Erdmann, P.; Petretta, M.; Schwitter, U. Chem. Biol 1995, 2, 367-375. (b) Breen, A. P.; Murphy, J. A. Free Radical Biol. Med. 1995, 18, 1033-1077. (c) Von Sonntag, C.; Hagen, U.; Schön-Bopp, A.; Schulte-Frohlinde, D. Adv. Radical Biol. 1981, 9, 109-142.
    • (1995) Free Radical Biol. Med. , vol.18 , pp. 1033-1077
    • Breen, A.P.1    Murphy, J.A.2
  • 5
    • 0000262774 scopus 로고
    • For reviews see: (a) Giese, B.; Beyrich-Graf, X.; Erdmann, P.; Petretta, M.; Schwitter, U. Chem. Biol 1995, 2, 367-375. (b) Breen, A. P.; Murphy, J. A. Free Radical Biol. Med. 1995, 18, 1033-1077. (c) Von Sonntag, C.; Hagen, U.; Schön-Bopp, A.; Schulte-Frohlinde, D. Adv. Radical Biol. 1981, 9, 109-142.
    • (1981) Adv. Radical Biol. , vol.9 , pp. 109-142
    • Von Sonntag, C.1    Hagen, U.2    Schön-Bopp, A.3    Schulte-Frohlinde, D.4
  • 20
    • 84920294622 scopus 로고    scopus 로고
    • The constants were determined according to ref 12. The data are collected in the Supporting Information
    • The constants were determined according to ref 12. The data are collected in the Supporting Information.
  • 22
    • 33747565073 scopus 로고
    • Giese, B.; Beyrich-Graf, X.; Burger, J.; Kesselheim, C.; Senn, M.; Schäfer, T. Angew. Chem. 1993, 105, 1850-1852; Angew. Chem., Int. Ed. Engl. 1993, 32, 1742-1744.
    • (1993) Angew. Chem., Int. Ed. Engl. , vol.32 , pp. 1742-1744
  • 24
    • 0000557695 scopus 로고
    • revision B.2: Frisch, M. J.; Trucks, G. W.; Schlegel, H. B.; Gill, P. M. W.; Johnson, B. G.; Robb M. A.; Cheeseman, J. R.; Keith, T.; Petersson, G. A.; Montgomery, J. A.; Raghavachari, K.; Al-Laham, M. A.; Zakrzewski, V. G.; Ortiz, J. V.; Foresman, J. B.; Cioslowski, J.; Stefanov, B. B.; Nanayakkara, A.; Challacombe, M.; Peng, C. Y.; Ayala, P. Y.; Chen, W.; Wong, M. W.; Andres, J. L.; Replogle, E. S.; Gomperts, R.; Martin, R. L.; Fox, D. J.; Binkley, J. S.; Defrees, D. J.; Baker, J.; Stewart, J. P.; Head-Gordon, M.; Gonzalez, C.; Pople, J. A. Gaussian, Inc., Pittsburgh, PA, 1995
    • 2O elimination in 1,2-dihydroxy radicals was discussed in Zipse, H. J. Am. Chem. Soc. 1995, 117, 11798-11806.
    • (1995) J. Am. Chem. Soc. , vol.117 , pp. 11798-11806
    • Zipse, H.1
  • 26
    • 84920294621 scopus 로고    scopus 로고
    • note
    • -1 higher than the ground state) was checked by frequency calculation, and only one imaginary frequency was found. An IRC calculation was performed to verify to which educt and products the transition state leads.
  • 30
    • 84920294620 scopus 로고    scopus 로고
    • note
    • (a) The measured average radius of precursor 52 (0.017 M in water) was 37 nm, which is well beyond the maximum radius of spherical micelles (<10 nm). (b) The measurements were done on a ALV-125 laser light scattering spectrometer/goniometer with a ALV-5000IE correlator at 20 °C.
  • 34
    • 84920294619 scopus 로고    scopus 로고
    • note
    • -1, respectively. The concentration of 55 depended linearly on the dose of γ-irradiation.
  • 37
    • 84920294618 scopus 로고    scopus 로고
    • note
    • 2 leads to a substituted 2-keto-1,2-propanediol.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.