Discovery of an inhibitor of a transcription factor using small molecule microarrays and diversity-oriented synthesis

Journal of the American Chemical Society

Volumn 125, Issue 28, 2003, Pages 8420-8421

  Koehler, Angela N ^a   Shamji, Alykhan F ^a   Schreiber, Stuart L ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; DEOXYRIBONUCLEOPROTEIN; GALACTOSAMINIDASE; GLUTAMATE DEHYDROGENASE; HAPTAMIDE A; HAPTAMIDE B; HYBRID PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; PROTEIN INHIBITOR; PROTEIN SUBUNIT; PROTOZOAL PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANTIBODY AFFINITY; ANTIBODY LABELING; ARTICLE; CELL PROLIFERATION; DISSOCIATION CONSTANT; DRUG MECHANISM; DRUG POTENCY; DRUG SYNTHESIS; GENE DELETION; GROWTH INHIBITION; IC 50; IMMUNOASSAY; IMMUNOMODULATION; INHIBITION KINETICS; PROTEIN BINDING; PROTEIN DNA INTERACTION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN SYNTHESIS INHIBITION; REPORTER GENE; STRUCTURE ACTIVITY RELATION; YEAST;

AMIDES; CCAAT-BINDING FACTOR; COMBINATORIAL CHEMISTRY TECHNIQUES; FUNGAL PROTEINS; GLUTATHIONE TRANSFERASE; KINETICS; PYRANS; RECOMBINANT FUSION PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; SURFACE PLASMON RESONANCE; TRANSCRIPTION FACTORS;

EID: 0038713943     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0352698     Document Type: Article

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