Detection of p53 deletions using fish technique in the HL-60, Daudi, Raji and K-562 cell lines

Experimental Oncology

Volumn 25, Issue 1, 2003, Pages 33-35

  Konac, E ^a   Ergun, M A ^a   Sahin, F I ^a   Ekmekci, A ^a  

^a GAZI UNIVERSITY   (Turkey)

Author keywords

Cell line; FISH; Loss of heterozygosity; p53 mutation

Indexed keywords

PROTEIN P53;

ANEUPLOIDY; ARTICLE; BURKITT LYMPHOMA; CANCER CELL CULTURE; CELL CYCLE; CELL STRAIN HL 60; CELL STRAIN K 562; CENTROMERE; CHROMOSOME 17; CLINICAL ARTICLE; CONTROLLED STUDY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE DELETION; GENE MUTATION; HETEROZYGOSITY; HUMAN; HUMAN CELL; INTERPHASE; METAPHASE; ONCOGENE; SIGNAL TRANSDUCTION; BLOOD; BLOOD SAMPLING; CANCER DIAGNOSIS; DAUDI CELL; IN SITU HYBRIDIZATION; RAJI CELL;

EID: 0038709518     PISSN: 02043564     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Amiel A, Arbov L, Manoy Y. Monoallelic p53 deletion in chronic lymphocytic leukemia detected by interphase cytogenetics. Cancer Genet Cytogenet 1997; 97: 97-100.
2. Capoulade C, Lluis MM, Karine C. Apoptosis of tumoral and nontumoral lymphoid cells is induced by both mdm2 and p53 antisense oligodeoxynucleotides. Blood 2001; 97: 1043-9.
3. Furuwatari C, Yagi A, Yamagami O. A comprehensive system to explore p53 mutations. Am J Clin Pathol 1998; 110: 368-73.
4. Juliusson G, Gahrton G. Chromosome aberrations in B-cell chronic lymphocytic leukemia. Cancer Genet Cytogenet 1990; 45: 143-60.
5. Lane DP, Benchimal S. P53: oncogene or anti-oncogene? Genes Dev 1990; 4: 1-8.
6. Nigro JM, Baker SJ, Preisinger AC. Mutations in the p53 gene occur in diverse human tumour types. Nature 1989;342:705-7.
7. Preudhomme C, Dervile I, Wattel E. Clinical significance of p53 mutations in newly diagnosed Burkitt's lymphoma and acute lymphoblastic leukemia: a report of 48 cases. J Clin Oncol 1995; 13: 812-20.
8. Winman KG, Magnusson KP, Ramqvist T, Klein G. Mutant p53 detected in a majority of Burkitt lymphoma cell lines by monoclonal antibody Pab240. Oncogene 1991; 6: 1633-9.
9. Wong Y, Schwedes JF, Parks D, Mann K, Tegtmeyer P. Interaction of p53 with its concensus DNA-binding site. Mol Cell Biol 1995; 15: 2157-65.
10. Yoshifumi O, Furuwatari C. Combination of nonradioisotopic techniques as an efficient screening method to detect p53 mutations. Biotech Lab International 1999; 18-20 pp.