Effectiveness of long-term heparin-induced extracorporeal LDL precipitation (HELP) in improving coronary calcifications

International Journal of Artificial Organs

Volumn 26, Issue 3, 2003, Pages 252-255

  Ramunni, Alfonso ^a   Morrone, L F ^a   Baldassarre, G ^a   Montagna, E ^a   Saracino, A ^a   Coratelli, P ^a  

^a UNIVERSITY OF BARI   (Italy)

Author keywords

Coronary calcification; Familial hypercholesterolemia; HELP system; LDL apheresis

Indexed keywords

BONE; CARDIOLOGY; CHOLESTEROL; DISEASES; HEART; PATIENT TREATMENT;

CORONARY ANGIOGRAPHY; CORONARY CALCIFICATIONS; CORONARY HEART DISEASE; FAMILIAL HYPERCHOLESTEROLEMIA; HEPARIN-INDUCED EXTRACORPOREAL LDL PRECIPITATION SYSTEM; LDL-APHERESIS; MEAN VALUES; PRECIPITATION SYSTEMS; STENOSES; TOTAL CHOLESTEROLS;

BIOMINERALIZATION;

CHOLESTEROL; FIBRINOGEN; HEPARIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL; SIMVASTATIN;

ADULT; ANGINA PECTORIS; ANGIOCARDIOGRAPHY; APHERESIS; ARTERY CALCIFICATION; ARTICLE; ATHEROSCLEROTIC PLAQUE; BLOOD FLOW; BODY WEIGHT; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CASE REPORT; CHOLESTEROL BLOOD LEVEL; CLINICAL FEATURE; CORONARY ARTERY ATHEROSCLEROSIS; CORONARY ARTERY BYPASS SURGERY; CORONARY ARTERY OBSTRUCTION; FAMILIAL HYPERCHOLESTEROLEMIA; FEMALE; FIBRINOGEN BLOOD LEVEL; HEMOFILTRATION; HEPARIN INDUCED EXTRACORPOREAL LOW DENSITY LIPOPROTEIN PRECIPITATION; HIGH RISK PATIENT; HUMAN; ISCHEMIC HEART DISEASE; PHYSICAL EXAMINATION; PLASMA VOLUME; PRECIPITATION; SAPHENOUS VEIN GRAFT; STATISTICAL ANALYSIS;

EID: 0038707289     PISSN: 03913988     EISSN: None     Source Type: Journal    
DOI: 10.1177/039139880302600312     Document Type: Article

References (17)

1. Bambauer R, Schiel R, Latza R. Current topics on low-density lipoprotein apheresis. Ther Apher 2001; 5: 293-300.
2. Stamier J, Wenrworth D, Neaton JD. Is relationship between serum cholesterol and risk of premature death from coronary heart disease continuous and graded? JAMA 1986; 8: 2823-28.
3. Kannel WB. High-density lipoproteins: Epidemiologic profile and risks of coronary artery disease. Am J Cardiol 1983; 52 (suppl B): 9B-12B.
4. Wannamethee G, Shaper AG, Shincup PH, Walter M. Low serum cholesterol concentrations and mortality in middle aged British men. Br Med J 1995; 311: 409-13.
5. Brett AS. Treating hypercholesterolemia: How should practising physicians interpret the published data for patients? N Engl J Med 1989; 321: 676-80.
6. Laaf A. Management of hypercholesterolemia: Are preventive interventions advisable? N Engl J Med 1989; 321: 680-4.
7. Yudkin JS. How can we best prolong life? Benefits of coronary risk factor reduction in non-diabetic and diabetic subjects. Br Med J 1993; 306: 1313-8.
8. Epstein FM. Beyond cholesterol. N Engl J Med 1989; 320: 915-24.
9. Anderson TJ, Meredith IT, Yeung AC, Frei B, Selwyn AP, Ganz P. The effect of cholesterol lowering and antioxidant therapy on endothelium-dependent coronary vasomotion. N Engl J Med 1995; 332: 482-8.
10. Treasure CB, Klein JL, Weintraube WS, Talley JD, Stillabower ME, Kosinski AS, Zhang J, Boccuzzi SJ, Cedarhoim JC, Alexander RW. Beneficial effects of cholesterol-lowering therapy on coronary endothelium in patients with coronary artery disease. N Engl J Med 1995; 332: 481-7.
11. Galle J, Bassenge E. Influence of low density lipoproteins (LDL) on the reactivity of the atherosclerotic arteries. Z Kardiol 1991; 80 (suppl 9): S15-20.
12. Schuff-Werner P, Gohlke H, Bartmann U, Baggio G, Corti MC, Diesenbacher A, Eisenbauer T, Grutzmacher P, Keller K, Kettner U, Kleophas W, Koster W, Olbricht CR, Richter WO, Seidel D and the HELP-Study Group. The HELP-LDL-Apheresis Multicenter Study, an angiographically assessed trial on the role of LDL apheresis in the secondary prevention of coronary heart disease. II. Final evaluation of the effect of regular treatment on LDL-cholesterol plasma concentrations and the course of coronary heart disease. Eur J Clin Invest 1994; 24: 724-32.
13. Koga N, Iwata Y. Pathological and angiographic regression of coronary atherosclerosis by LDL-apheresis in a patient with familial hypercholesterolemia. Atherosclerosis 1991; 90: 9-21.
14. Matsuzaki M, Hirarnori K, Kitabatake A, Hishida H, Kujii T, Sakuma I, Fukami K, Honda T, Ogawa H. Intravascular ultrasound analysis of coronary plaque regression by LDL-apheresis in patients with familial hypercholesterolemia: The LDL-Apheresis, Coronary Morphology and Reserve Trial (LACMART) (Abstract). Circulation 1999; 100 (suppl 1): S1-82.
15. Mabuchi H, Koizumi J, Shimizu M, Kajnami K, Miyamoto S, Veda K, Takegoshi T. Long-term efficacy of low-density lipoprotein apheresis on coronary heart disease in familial hypercholesterolemia. Am J Cardiol 1998; 82: 1489-95.
16. Mohlenkamp S, Park JW, Gronemeyer D, Schwartz RS, Erbel R. Improved coronary risk assessment with electron beam computed tomography in an asymptomatic female with hypercholesterolemia. Mayo Clin Proc 1999; 74: 1017-20.
17. Hoffmann U, Bodlaj G, Derfier K, Bernhard C, Wicke L, Herold, Kostner K. Quantification of coronary artery calcification in patient with FH using EBCT. Eur J Clin Invest 2001; 31: 471-5.