The clinicopathological spectrum of Rosenthal fibre encephalopathy and Alexander's disease: A case report and review of the literature

Journal of Neurology Neurosurgery and Psychiatry

Volumn 74, Issue 6, 2003, Pages 807-810

  Jacob, J ^a   Robertson, N J ^a   Hilton, D A ^a  

^a DERRIFORD HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DAPSONE; DEXAMETHASONE; GLIAL FIBRILLARY ACIDIC PROTEIN; LAMIVUDINE; PYRIMETHAMINE; ZALCITABINE; ZIDOVUDINE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; ALEXANDER DISEASE; ARTICLE; AUTOPSY; BRAIN DISEASE; CASE REPORT; CLINICAL FEATURE; DEMYELINATION; GENE MUTATION; HUMAN; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; ROSENTHAL FIBER ENCEPHALOPATHY; SYMPTOMATOLOGY;

ADULT; AIDS DEMENTIA COMPLEX; ALEXANDER DISEASE; ALPHA-CRYSTALLIN B CHAIN; FATAL OUTCOME; GLIAL FIBRILLARY ACIDIC PROTEIN; HUMANS; MALE;

EID: 0038692416     PISSN: 00223050     EISSN: None     Source Type: Journal    
DOI: 10.1136/jnnp.74.6.807     Document Type: Article

References (28)

1. Alexander A. Progressive fibrinoid degeneration of fibrillary astrocytes associated with mental retardation in a hydrocephalic infant. Brain 1949;72:373.
2. Seil FJ, Schochet SS Jr, Earle KM. Alexander's disease in an adult. Report of a case. Arch Neural 1968;19:494-502.
3. Walls TJ, Jones RA, Cartlidge N, et al. Alexander's disease with Rosenthal fibre formation in an adult. J Neural Neurosurg Psychiatry 1984;47:399-403.
4. Herndon RM, Rubinstein LJ, Freeman JM, et al. Light and electron microscopic observations on Rosenthal fibers in Alexander's disease and in multiple sclerosis. J Neuropathol Exp Neurol 1970;29:524-51.
5. Spalke G, Mennel HD. Alexander's disease in an adult: clinicopathologic study of a case and review of the literature. Clin Neuropathol 1982;1:106-12.
6. Iwaki T, Kume-Iwaki A, Liem RK, et al. Alpha B-crystallin is expressed in non-lenticular tissues and accumulates in Alexander's disease brain. Cell 1989;57:71-8.
7. Johnson AB, Bettica A. On-grid immunogold labeling of glial intermediate filaments in epoxy-embedded tissue. Am J Anat 1989;185:335-41.
8. Goldman JE, Corbin E. Rosenthal fibers contain ubiquitinated alpha B-crystallin. Am J Pathol 1991;139:933-8.
9. Iwaki T, Iwaki A, Tateishi J, et al. Alpha B-crystallin and 27-kd heat shock protein are regulated by stress conditions in the central nervous system and accumulate in Rosenthal fibers. Am J Pathol 1993;143:487-95.
10. Dinda AK, Sarkar C, Roy S. Rosenthal fibres: an immunohistochemical, ultrastructural and immunoelectron microscopic study. Acta Neuropathol 1990;79:456-60.
11. Riggs JE, Schochet SS Jr, Nelson J. Asymptomatic adult Alexander's disease: entity or nosological misconception? Neurology 1988;38:152-4.
12. Wilson SP, Al-Sarraj S, Bridges LR. Rosenthal fiber encephalopathy presenting with demyelination and Rosenthal fibers in a solvent abuser: adult Alexander's disease? Clin Neuropathol 1996;15:13-16.
13. Herndon RM. Is Alexander's disease a nosologic entity or a common pathologic pattern of diverse etiology? J Child Neural 1999;14:275-6.
14. Hilton DA, Love S, Fletcher A, et al. Absence of Epstein-Barr virus RNA in multiple sclerosis: a study using in situ hybridisation. J Neural Neurosurg Psychiatry 1994;57:975-6.
15. Howard RS, Greenwood R, Gawler J, et al. A familial disorder associated with palatal myoclonus, other brainstem signs, tetraparesis, ataxia and Rosenthal fibre formation. J Neural Neurosurg Psychiatry 1993;56:977-81.
16. Schwankhaus JD, Parisi JE, Gulledge WR, et al. Hereditary adult-onset Alexander's disease with palatar myoclonus, spastic paraparesis, and cerebellar ataxia. Neurology 1995;45:2266-71.
17. Friedman JH, Ambler M. Progressive parkinsonism associated with Rosenthal fibers: senile-onset Alexander's disease? Neurology 1992;42:1733-5.
18. Brenner M, Johnson AB, Boespflug-Tanguy O, et al. Mutations in GFAP, encoding glial fibrillary acidic protein, are associated with Alexander disease. Nat Genet 2001;27:117-20.
19. van der Knaap MS, Naidu S, Breiter SN, et al. Alexander disease: diagnosis with MR imaging. Am J Neuroradiol 2001;22:541-52.
20. Rodriguez D, Gauthier F, Bertini E, et al. Infantile Alexander disease: spectrum of GFAP mutations and genotype-phenotype correlation. Am J Hum Genet 2001;69:1134-40.
21. Messing A, Goldman JE, Johnson AB, et al. Alexander disease: new insights from genetics. J Neuropathol Exp Neural 2001;60:563-73.
22. Messing A, Head MW, Galles K, et al. Fatal encephalopathy with astrocyte inclusions in GFAP transgenic mice. Am J Pathol 1998;152:391-8.
23. Klein H. Alexander'sche Krankheit bei einer Erwaschsenen. Zentralbl ges Neural Psychiat 1970;197:338.
24. Duckett S, Schwartzman RJ, Osterholm J, et al. Biopsy diagnosis of familial Alexander's disease. Pediatr Neurosurg 1992;18:134-8.
25. Kepes JJ, Ziegler DK. Alexander's disease in an adult (leukodystrophy with Rosenthal fibres). Missouri Med (Suppl) 1972;69:23-5.
26. Tihen WS. Central pontine myelinolysis and Rosenthal fibers of the brainstem. Association with emaciation and prolonged intravenous hyperalimentation. Neurology 1972;22:710-16.
27. Mastri AR, Sung JH. Diffuse Rosenthal fiber formation in the adult: a report of four cases. J Neuropathol Exp Neurol 1973;32:424-36.
28. Softer D, Horoupian DS. Rosenthal fibers formation in the central nervous system. Its relation to Alexander's disease. Acta Neuropathol (Berl) 1979;47:81-4.