Tramadol inhibits rat detrusor overactivity caused by dopamine receptor stimulation

Journal of Urology

Volumn 170, Issue 1, 2003, Pages 272-275

  Pehrson, Rikard ^b   Andersson, Karl Erik ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b NONE

Author keywords

Apomorphine; Bladder; Rats, Sprague Dawley; Tramadol; Urinary incontinence

Indexed keywords

APOMORPHINE; DESMOPRESSIN; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; TRAMADOL;

ANALGESIA; ANESTHESIA MECHANISM; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLADDER; CONTROLLED STUDY; CYSTOMETRY; DETRUSOR MUSCLE; DIURESIS; DOPAMINERGIC ACTIVITY; DRUG ACTIVITY; DRUG RECEPTOR BINDING; FEMALE; FEMORAL VEIN; MICTURITION; NONHUMAN; PRIORITY JOURNAL; RAT; URINARY TRACT DISEASE;

EID: 0038679278     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ju.0000062528.54550.65     Document Type: Article

References (20)

1. Fowler, C. J.: Urinary disorders in Parkinson's disease and multiple system atrophy. Funct Neurol, 16: 277, 2001
2. Andersson, K. E.: Treatment of the overactive bladder: possible central nervous system drug targets. Urology, 59: 18, 2002
3. Jackson, D. M. and Westlind-Danielsson, A.: Dopamine receptors: molecular biology, biochemistry and behavioural aspects. Pharmacol Ther, 64: 291, 1994
4. Yoshimura, N., Mizuta, E., Yoshida, O. and Kuno, S.: Therapeutic effects of dopamine D1/D2 receptor agonists on detrusor hyper-reflexia in 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-lesioned parkinsonian cynomolgus monkeys. J Pharmacol Exp Ther, 286: 228, 1998
5. Kontani, H., Inoue, T. and Sakai, T.: Effects of apomorphine on urinary bladder motility in anaesthetized rats. Japan J Pharmacol, 52: 59, 1990
6. Frink, M. C., Hennies, H. H., Englberger, W., Haurand, M. and Wilffert, B.: Influence of tramadol on neurotransmitter systems of the rat brain. Arzneimittelforschung, 46: 1029, 1996
7. Pandita, R. K., Pehrson, R., Christoph, T., Friderichs, E. and Andersson, K.-E.: Actions of tramadol on micturition in awake, freely moving rats. Unpublished data
8. Lot, T. Y.: Mechanisms of action of dopamine in the peripheral nervous system of chicks and rats. J Pharm Pharmacol, 45: 896, 1993
9. van Dijken, H., Dijk, J., Voom, P. and Holstege, J. C.: Localization of dopamine D2 receptor in rat spinal cord identified with immunocytochemistry and in situ hybridization. Eur J Neurosci, 8: 621, 1996
10. Seki, S., Igawa, Y., Kaidoh, K., Ishizuka, O., Nishizawa, O. and Andersson, K. E.: Role of dopamine D1 and D2 receptors in the micturition reflex in conscious rats. Neurourol Urodyn, 20: 105, 2001
11. Yokoyama, O., Yoshiyama, M., Namiki, M. and de Groat, W. C.: Glutamatergic and dopaminergic contributions to rat bladder hyperactivity after cerebral artery occlusion. Am J Physiol, 276: R935, 1999
12. Hurd, Y. L., Suzuki, M. and Sedvall, G. C.: D1 and D2 dopamine receptor mRNA expression in whole hemisphere sections of the human brain. J Chem Neuroanat, 22: 127, 2001
13. Yokoyama, O., Yoshiyama, M., Namiki, M. and de Groat, W. C.: Interaction between D2 dopaminergic and glutamatergic excitatory influences on lower urinary tract function in normal and cerebral-infarcted rats. Exp Neurol, 169: 148, 2001
14. Belayev, L., Alonso, O. F., Busto, R., Zhao, W. and Ginsberg, M. D.: Middle cerebral artery occlusion in the rat by intraluminal suture. Neurological and pathological evaluation of an improved model. Stroke, 27: 1616, 1996
15. Obeso, J. A., Rodriguez-Oroz, M. C., Rodriguez, M., Lanciego, J. L., Artieda, J., Gonzalo, N. et al: Pathophysiology of the basal ganglia in Parkinson's disease. Trends Neurosci, 23: S8, 2000
16. Wolters, E. C., Tissingh, G., Bergmans, P. L. and Kuiper, M. A.: Dopamine agonists in Parkinson's disease. Neurology, suppl., 45: S28, 1995
17. Raffa, R. B. and Friderichs, E.: The basic science aspect of tramadol hydrochloride. Pain Rev, 3: 249, 1996
18. King, M. A., Bradshaw, S., Chang, A. H., Pintar, J. E. and Pasternak, G. W.: Potentiation of opioid analgesia in dopamine2 receptor knock-out mice: evidence for a tonically active anti-opioid system. J Neurosci, 21: 7788, 2001
19. Durant, P. A. and Yaksh, T. L.: Drug effects on urinary bladder tone during spinal morphine-induced inhibition of the micturition reflex in unanesthetized rats. Anesthesiology, 68: 325, 1988
20. Di Michele, S., Sillen, U., Engel, J. A., Hjälmås, K., Rubenson, A. and Söderpalm, B.: Desmopressin and vasopressin increase locomotor activity in the rat via a central mechanism: implications for nocturnal enuresis. J Urol, 156: 1164, 1996