Evaluation of D3/D4 lymph node dissection for patients with grossly N2 positive advanced gastric cancer

Hepato-Gastroenterology

Volumn 50, Issue 52, 2003, Pages 1178-1182

  Gunji, Yoshio ^a   Suzuki, Takao ^a   Kobayashi, Susumu ^a   Hori, Seiji ^a   Hayashi, Hideki ^a   Shimada, Hideaki ^a   Matsubara, Hisahiro ^a   Nabeya, Yoshihiro ^a   Ochiai, Takenori ^a  

^a CHIBA UNIVERSITY   (Japan)

Author keywords

D2 lymphadenectomy; D3 D4 lymphadenectomy; Gastric cancer

Indexed keywords

ADULT; ARTICLE; CANCER INVASION; CANCER MORTALITY; CANCER RECURRENCE; CANCER STAGING; CANCER SURVIVAL; CONTROLLED STUDY; FEMALE; GASTRECTOMY; HUMAN; LYMPH NODE DISSECTION; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RISK ASSESSMENT; STATISTICAL ANALYSIS; STOMACH CANCER; SURGICAL MORTALITY; TREATMENT OUTCOME;

FEMALE; GASTRECTOMY; HUMANS; LYMPH NODE EXCISION; MALE; MIDDLE AGED; NEOPLASM STAGING; PROPORTIONAL HAZARDS MODELS; STOMACH NEOPLASMS; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 0038677052     PISSN: 01726390     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Japanese Research Society for Gastric Cancer: In: Nishi M, Omori Y, Miwa K (Eds.). Japanese classification of gastric carcinoma. Tokyo: Kanehara, 1995; pp. 1-47.
2. Hochwald SN, Brennan MF, Klimstra DS, Kim S, Karpeh MS: Is lymphadenectomy necessary for early gastric cancer? Ann Surg Oncol 1999; 6:664-670.
3. Nakamura K, Morisaki T, Sugitani A, Ogawa T, Uchiyama A, Kinukawa N, Tanaka M: An early gastric carcinoma treatment strategy based on analysis of lymph node metastasis. Cancer 1999; 85:1500-1505.
4. Roukos DH: Current advances and changes in treatment strategy may improve survival and quality of life in patients with potentially curable gastric cancer. Ann Surg Oncol 1999; 6:46-56.
5. Cuschieri A, Weeden S, Fielding J, Bancewicz J, Craven J, Joypaul V, Sydes M, Fayers P: Patient survival after D1 and D2 resections for gastric cancer: long-term results of the MRC randomized surgical trial. Surgical Co-operative Group. Br J Cancer 1999; 79:1522-1530
6. Bonenkamp JJ, Hermans J, Sasako M, van de Velde CJ: Extended lymph-node dissection for gastric cancer. Dutch Gastric Cancer Group. N Engl J Med 1999; 25:908-914.
7. de Manzoni G, Verlato G, Guglielmi A, Laterza E, Tomezzoli A, Pelosi G, Di LA, Cordiano C: Classification of lymph node metastases from carcinoma of the stomash: comparison of the old (1987) and new (1997) TNM systems. World J Surg 1999; 23:664-669.
8. Hayashi H, Ochiai T, Suzuki T, Shimada H, Hori S, Takeda A, Miyazawa Y: Superiority of a new UICC-TNM staging system for gastric carcinoma. Surgery 2000; 127:129-135.
9. Volpe CM, Driscoll DL, Miloro SM, Douglass HO Jr: Survival benefit of extended D2 resection for proximal gastric cancer. J Surg Oncol 1997; 64:231-236.
10. Roukos DH, Lorenz M, Encke A: Evidence of survival benefit of extended (D2) lymphadenectomy in western patients with gastric cancer based on a new concept: a prospective long-term follow-up study. Surgery 1998; 123:573-578.
11. Llanos O, Guzman S, Pimentel F, Ibanez L, Duarte I: Results of surgical treatment of gastric cancer. Dig Surg 1999; 16:385-388.
12. Onate-Ocana LF, Aiello-Crocifoglio V, Mondragon-Sanchez R, Ruiz-Molina JM: Survival benefit of D2 lymphadenectomy in patients with gastric adenocarcinoma. Ann Surg Oncol 2000; 7:210-217.
13. Siewert JR, Kestlmeier R, Busch R, Bottcher K, Roder JD, Muller J, Fellbaum C, Hofler H: Benefits of D2 lymph node dissection for patients with gastric cancer and pN0 and pN1 lymph node metastases. Br J Surg 1996; 83:1144-1147.
14. Bruno L, Nesi G, Montinaro F, Carassale G, Boddi V, Bechi P, Cortesini C: Clinicopathologic characteristics and outcome indicators in node-negative gastric cancer. J Surg Oncol 2000; 74:30-32.
15. Harrison LE, Karpeh MS, Brennan MF: Extended lymphadenectomy is associated with a survival benefit for node-negative gastric cancer. J Gastrointest Surg 1998; 2:126-131.
16. Maeta M, Yamashiro H, Saito H, Katano K, Kondo A, Tsujitani S, Ikeguci M, Kaibara N: A prospective pilot study of extended (D3) and superextended para-aortic lymphadenectomy (D4) in patients with T3 or T4 gastric cancer managed by total gastrectomy. Surgery 1999; 125:325-331.
17. Isozaki H, Okajima K, Fujii K, Nomura E, Izumi N, Mabuchi H, Nakamura M, Hara H: Effectiveness of paraaortic lymph node dissection for advanced gastric cancer. Hepatogastroenterology 1999; 46:549-554.
18. Ikeguchi M, Oka S, Gomyo Y, Tsujitani S, Maeta M, Kaibara N: Prognostic benefit of extended radical lymphadenectomy for patients with gastric cancer. Anticancer Res 2000; 20(2B):1285-1289.
19. Volpe CM, Koo J, Miloro SM, Driscoll DL, Nava HR, Douglass HO Jr: The effect of extended lymphadenectomy on survival in patients with gastric adenocarcinoma. J Am Coll Surg 1995; 181:56-64.
20. Kunisaki C, Shimada H, Yamaoka H, Wakasugi J, Takahashi M, Akiyama H, Nomura M, Moriwaki Y: Significance of para-aortic lymph node dissection in advanced gastric cancer. Hepatogastroenterology 1999; 46:2635-2642.
21. Siewert JR, Bottcher K, Roder JD, Busch R, Hermanek P, Meyer HJ: Prognostic relevance of systematic lymph node dissection in gastric carcinoma. German Gastric Carcinoma Study Group. Br J Surg 1993; 80:1015-1018.
22. Kodera Y, Yamamura Y, Shimizu Y, Torii A, Hirai T, Yasui K, Morimoto T, Kato T, Kito T: Lymph node status assessment for gastric carcinoma: is the number of metastatic lymph nodes really practical as a parameter for N categories in the TNM Classification? Tumor Node Metastasis. J Surg Oncol 1998; 69:15-20.
23. Fujii K, Isozaki H, Okajima K, Nomura E, Niki M, Sako S, Izumi N, Mabuchi H, Nishiguchi K, Tanigawa N: Clinical evaluation of lymph node metastasis in gastric cancer defined by the fifth edition of the TNM classification in comparison with the Japanese system. Br J Surg 1999; 86:685-689.
24. Cuschieri A, Fayers P, Fielding J, Craven J, Bancewicz J, Joypaul V, Cook P: Postoperative morbidity and mortality after D1 and D2 resections for gastric cancer: preliminary results of the MRC randomized controlled surgical trial. The Surgical Cooperative Group. Lancet 1996; 347:995-999.
25. Schmid A, Thybusch A, Kremer B, Henne-Bruns D: Differential effects of radical D2-lymphadenectomy and splenectomy in surgically treated gastric cancer patients. Hepatogastroenterology 2000; 47:579-585.
26. Kodama I, Kofuji K, Yano S, Shinozaki K, Murakami N, Hori H, Takeda J, Shirouzu K: Lymph node metastasis and lymphadenectomy for carcinoma in the gastric cardia: clinical experience. Int Surg 1998; 83:205-209.