A carbon-carbon bond formation by the reaction of 4-chloro-6-methyl-3-phenylethynyl-2H-pyran-2-one with active methylene derivatives

Heterocycles

Volumn 42, Issue 2, 1996, Pages 789-794

  Azuma, Yutaka ^a   Sato, Atsuko ^a   Morone, Mieko ^a  

^a TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0038675894     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/COM-95-S86     Document Type: Article

References (6)

1. A. Cantos, P. De March, M. Moreno-Manas, A. Pla, F. Sanchez-Ferrando, and A. Virgili, Bull. Chem. Soc. Jpn., 1987, 60, 4425;
2. Idem, Chem. Lett., 1986, 295.
3. Y. Azuma, A. Sato, and M. Morone, Heterocycles, 1993, 35, 599.
4. Y. Azuma, A. Sato, and M. Morone, Heterocycles, 1994, 38, 1573.
5. 60 % dispersion of NaH in mineral oil was washed several times by decantation with THF.
6. In the reaction of 2 with ethyl cyanoacetate, NaH was suspended into a mixture of THF (30ml) and DMF (20ml).