Pharmacokinetics and Clinical Utility of Sodium Bromide (NaBr) as an Estimator of Extracellular Fluid Volume in Horses

Journal of Veterinary Internal Medicine

Volumn 17, Issue 2, 2003, Pages 213-217

  Fielding, C Langdon ^a,b   Magdesian, K Gary ^a   Elliott, Denise A ^a,c   Craigmill, Arthur L ^a   Wilson, W David ^a   Carlson, Gary P ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

^c Waltham USA   (United States)

Author keywords

Fluid balance; Pharmacology

Indexed keywords

SODIUM BROMIDE; BROMIDE; SODIUM DERIVATIVE;

ARTICLE; BLOOD SAMPLING; BODY WEIGHT; CONFIDENCE INTERVAL; CONTROLLED STUDY; EQUILIBRIUM CONSTANT; EXTRACELLULAR FLUID; EXTRACELLULAR SPACE; FEMALE; HALF LIFE TIME; HORSE; NONHUMAN; STEADY STATE; ANIMAL; ELECTROLYTE BALANCE;

EQUIDAE; EQUUS CABALLUS;

ANIMALS; BROMIDES; EXTRACELLULAR SPACE; FEMALE; HORSES; SODIUM COMPOUNDS; WATER-ELECTROLYTE BALANCE;

EID: 0038656724     PISSN: 08916640     EISSN: None     Source Type: Journal    
DOI: 10.1892/0891-6640(2003)017<0213:PACUOS>2.3.CO;2     Document Type: Article

References (32)

1. Crandall LA, Anderson MX. Estimation of the state of hydration of the body by the amount of water available for the solution of sodium thiocyanate. Am J Dig Dis Nutr 1934;1:126-131.
2. Evans JW. Effect of fasting, gestation, lactation and exercise on glucose turnover in horses. J Anim Sci 1971;33:1001-1004.
3. Kohn CW, Muir WW, Sams R. Plasma volume and extracellular fluid volume in horses at rest and following exercise. Am J Vet Res 1978;59:871-874.
4. Muir WW, Kohn CW, Sam SR. Effects of furosemide on plasma volume and extracellular fluid volumes in horses. Am J Vet Res 1978;39:1688-1691.
5. Carlson GP, Harold D, Rumbaugh GE. Volume dilution of sodium thiocyanate as a measure of extracellular fluid volume in the horse. Am J Vet Res 1979;40:587-589.
6. Carlson GP, Rumbaugh GE, Harrold DR. Physiologic alterations produced by food and water deprivation during periods of high environmental temperatures. Am J Vet Res 1979;40:982-985.
7. Epstein V. Relationship between potassium administration, hyperkalaemia, and the electrocardiogram: An experimental study. Equine Vet J 1984;16:453-456.
8. Weir EG, Hastings AB. The distribution of bromide and chloride in tissues and body fluids. J Biol Chem 1939;129:547-558.
9. Vaiseman N, Koren G, Percharz P. Pharmacokinetics of oral and intravenous bromide in normal volunteers. J Toxicol Clin Toxicol 1986;24(5):403-413.
10. Trepanier LA, Babish JG. Pharmacokinetic properties of bromide in dogs after the intravenous and oral administration of single doses. Res Vet Sci 1995;58:248-251.
11. Pavelka S, Babicky A, Vobecky M, et al. Bromide kinetics and distribution in the rat. I. Biokinetics of Br82-bromide. Biol Trace Elem Res 2000;76(1):57-66.
12. 82Br as an extracellular water tracer in ruminants. In: International Atomic Energy Agency, ed. Isotope Studies on the Physiology of Domestic Animals. Vienna, Austria: IAEA; 1972:73-80.
13. Gamble JL, Robertson JS, Hannigan CA, et al. Chloride, bromide, sodium, and sucrose spaces in man. J Clin Invest 1953;32:483-489.
14. Cheek DB. Estimation of the bromide space with a modification of Conway's method. J Appl Physiol 1953;5:639-645.
15. Cardozo RH, Edelman IS. The volume of distribution of sodium thiosulfate as a measure of the extracellular fluid space. J Clin Invest 1952;31:280-290.
16. Scheinberg IH, Kowalski HJ. The binding of thiocyanate to albumin in normal human serum and defibrinated blood with reference to the determination of thiocyanate space. J Clin Invest 1950;29:475-482.
17. Miller ME, Cosgriff JM, Forbes GB. Bromide space determination using anion-exchange chromatography for measurement of bromide. Am J Clin Nutr 1989;50:168-171.
18. Wong WW, Sheng H, Morkeberg JC, et al. Measurement of extracellular water volume by bromide ion chromatography. Am J Clin Nutr 1989;50:1290-1294.
19. Yamaoka K, Nakagawa T, Uno T. Application of Akaike's information criterion (AIC) in the evaluation of linear pharmacokinetic equations. J Pharmacokinet Biopharm 1978;6:165-175.
20. Coghlan JP, Fan JS, Scoggins BA, et al. Measurement of extracellular fluid volume and blood volume in sheep. Aust J Biol Sci 1977;30:71-84.
21. Riviere JE. Comparative Pharmacokinetics: Principles, Techniques, and Applications, 1st ed. Ames, IA: Iowa State University Press; 1999:131-132.
22. Liggett AD, Jain AV, Blue JL. Pseudohyperchloremia associated with bromide intoxication in a goat herd. J Am Vet Med Assoc 1985;187:72-74.
23. Woodbury DM, Pippenger CE. Other antiepileptic drugs, bromides. In: Woodbury DM, Penry JK, Pippenger CE, eds. Antiepileptic Drugs. New York, NY: Raven Press; 1982:791-801.
24. Palmer JW, Clarke HT. The elimination of bromides from the bloodstream. J Biol Chem 1933;99:435-444.
25. Trepanier LA, Babish JG. Effect of dietary chloride content on the elimination of bromide by dogs. Res Vet Sci 1995;58:252-255.
26. Staffurth JS, Birchall I. The measurement of the extracellular fluid volume with radioactive bromine. Clin Sci 1960;19:45-53.
27. McMurray JD, Boling EA, Davis JM, et al. Body composition: Simultaneous determination of several aspects by the dilution principle. Metabolism 1958;7:651-667.
28. Persson SG, Ekman L, Lydin G, et al. Circulatory effects of splenectomy in the horse. II. Effects on plasma volume and total and circulating red cell volume. Zentralbl Veterinarmed A 1973;20:456-468.
29. Vaisman N, Pencharz MB, Koren G, et al. Comparison of oral and intravenous administration of sodium bromide for extracellular water measurements. Am J Clin Nutr 1987;46:1-4.
30. Meagher DM, Tasker JB. Effects of excitement and tranquilization on the equine hemogram. Mod Vet Pract 1972;53:41-43.
31. Marroum PJ, Webb AI, Aeschbacher G, Curry SH. Pharmacokinetics and pharmacodynamics of acepromazine in horses. Am J Vet Res 1994;55:1428-1433.
32. Trepanier LA, Van Schoick A, Schwark WS, et al. Therapeutic serum drug concentrations in epileptic dogs treated with potassium bromide alone or in combination with other anticonvulsants: 122 cases (1992-1996). J Am Vet Med Assoc 1998;213:1449-1453.