Effective protection of allogeneic stem cell recipients against aspergillosis by HEPA air filtration during a period of construction - A prospective survey

Journal of Hematotherapy and Stem Cell Research

Volumn 12, Issue 3, 2003, Pages 301-307

  Krüger, William H ^a,b   Zöllner, Bernhard ^a   Kaulfers, Paul Michael ^a   Zander, Axel R ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AIR CONDITIONING; AIR MONITORING; AIR POLLUTION; ARTICLE; ASPERGILLOSIS; ASPERGILLUS; CONTROLLED STUDY; DISEASE ASSOCIATION; FUNGUS SPORE; GRAVITY; HUMAN; MAJOR CLINICAL STUDY; MEASUREMENT; PARTICULATE MATTER; PATIENT CARE; PRIORITY JOURNAL; RECIPIENT; RELIABILITY; STEM CELL TRANSPLANTATION;

AIR; AIR MICROBIOLOGY; ASPERGILLOSIS; ASPERGILLUS; BONE MARROW TRANSPLANTATION; HEALTH FACILITY PLANNING; HUMANS; PATIENTS' ROOMS; SPORES, FUNGAL; STEM CELL TRANSPLANTATION; TRANSPLANTATION, HOMOLOGOUS;

EID: 0038648787     PISSN: 15258165     EISSN: None     Source Type: Journal    
DOI: 10.1089/152581603322023034     Document Type: Article

References (15)

1. Wald A, W Leisenring, JA van Burik and RA Bowden. (1997). Epidemiology of Aspergillus infections in a large cohort of patients undergoing bone marrow transplantation. J Infect Dis 175:1459-1466.
2. Meyers JD. (1990). Fungal infections in bone marrow transplant patients. Semin Oncol 17:10-13.
3. Denning DW. (1998). Invasive aspergillosis. Clin Infect Dis 26:781-803.
4. Barnes RA and TR Rogers. (1998). Control of an outbreak of nosocomial aspergillosis by laminar air-flow isolation. J Hosp Infect 14:89-94.
5. Oren I, N Haddad, R Finkelstein and JM Rowe. (2001). Invasive pulmonary aspergillosis in neutropenic patients during hospital construction: before and after chemoprophylaxis and institution of HEPA filters. Am J Hematol 66:257-262.
6. Krüger WH, RJ Hornung, B Hertenstein, WV Kern, N Kröger, P Ljungman and AR Zander. (2001). Practices of infectious disease prevention and management during hematopoietic stem cell transplantation: a survey from the European group for blood and marrow transplantation. J Hematother Stem Cell Res 10:895-903.
7. Beyer J, G Barzen, G Risse, C Weyer, K Miksits, K Dullenkopf, D Huhn and W Siegert. (1993). Aerosol amphotericin B for prevention of invasive pulmonary aspergillosis. Antimicrob Agents Chemother 37:1367-1369.
8. Krüger W, B Rüssmann, N Kröger, C Salomon, N Ekopf, HA Elsner, PM Kaulfers, D Mack, N Fuchs, M Dürken, H Kabisch, R Erttmann and AR Zander. (1999). Early infections in patients undergoing bone marrow or blood stem cell transplantation - a 7 year single centre investigation of 409 cases. Bone Marrow Transplant 23:589-597.
9. Raad I, H Hanna, C Osting, R Hachem, J Umphrey, J Tarrand, H Kantarjian and GP Bodey. (2002). Masking of neutropenic patients on transport from hospital rooms is associated with a decrease in nosocomial aspergillosis during construction. Infect Control Hosp Epidemiol 23:41-43.
10. Iwen PC, JC Davis, EC Reed, BA Winfield, and SH Hinrichs. (1994). Airborne fungal spore monitoring in a protective environment during hospital construction, and correlation with an outbreak of invasive aspergillosis. Infect Control Hosp Epidemiol 15:303-306.
11. Ascioglu S, JH Rex, B de Pauw, JE Bennett, J Bille, F Crokaert, DW Denning, JP Donnelly, JE Edwards, Z Erjavec, D Fiere, O Lortholary, J Maertens, JF Meis, TF Patterson, J Ritter, D Selleslag, PM Shah, DA Stevens and TJ Walsh. (2002). Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: an international consensus. Clin Infect Dis 34:7-14.
12. Friberg B, S Friberg and LG Burman. (1999). Inconsistent correlation between aerobic bacterial surface and air counts in operating rooms with ultra clean laminar air flows: proposal of a new bacteriological standard for surface contamination. J Hosp Infect 42:287-293.
13. Lai KK. (2001). A cluster of invasive aspergillosis in a bone marrow transplant unit related to construction and the utility of air sampling. Am J Infect Control 29:333-337.
14. Kolbe K, D Domkin, HG Derigs, S Bhakdi, C Huber and WE Aulitzky. (1997). Infectious complications during neutropenia subsequent to peripheral blood stem cell transplantation. Bone Marrow Transplant 19:143-147.
15. Jantunen E, P Ruutu, L Niskanen, L Volin, T Parkkali, P Koukila-Kahkola and T Ruutu. (1997). Incidence and risk factors for invasive fungal infections in allogeneic BMT recipients. Bone Marrow Transplant 19:801-808.