메뉴 건너뛰기




Volumn 54, Issue 1, 2003, Pages 98-104

Reassessment of the unbound concentrations of unconjugated bilirubin in relation to neurotoxicity in vitro

Author keywords

[No Author keywords available]

Indexed keywords

BILIRUBIN; CHLORIDE; GLUTAMIC ACID; HUMAN SERUM ALBUMIN;

EID: 0038647817     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/01.PDR.0000067486.79854.D5     Document Type: Article
Times cited : (67)

References (46)
  • 2
    • 0025150585 scopus 로고
    • Antioxidant activities of bile pigments: Biliverdin and bilirubin
    • Stocker R, McDonagh AF, Glazer AN, Ames BN 1990 Antioxidant activities of bile pigments: biliverdin and bilirubin. Methods Enzymol 186:301-309
    • (1990) Methods Enzymol , vol.186 , pp. 301-309
    • Stocker, R.1    McDonagh, A.F.2    Glazer, A.N.3    Ames, B.N.4
  • 3
    • 0025281223 scopus 로고
    • Is bilirubin good for you?
    • McDonagh AF 1990 Is bilirubin good for you? Clin Perinatol 17:359-370
    • (1990) Clin Perinatol , vol.17 , pp. 359-370
    • McDonagh, A.F.1
  • 4
    • 0022577995 scopus 로고
    • Breast milk jaundice in the newborn. A real entity
    • Schneider AP 1986 Breast milk jaundice in the newborn. A real entity. JAMA 255:3270-3274
    • (1986) JAMA , vol.255 , pp. 3270-3274
    • Schneider, A.P.1
  • 5
    • 0030629822 scopus 로고    scopus 로고
    • Bilirubin metabolism and kernicterus
    • Gourley GR 1997 Bilirubin metabolism and kernicterus, Adv Pediatr 44:173-229
    • (1997) Adv Pediatr , vol.44 , pp. 173-229
    • Gourley, G.R.1
  • 6
    • 0033950424 scopus 로고    scopus 로고
    • The blood-brain barrier and bilirubin encephalopathy
    • Wennberg RP 2000 The blood-brain barrier and bilirubin encephalopathy. Cell Mol Neurobiol 20:97-109
    • (2000) Cell Mol Neurobiol , vol.20 , pp. 97-109
    • Wennberg, R.P.1
  • 7
    • 0018812596 scopus 로고
    • Binding of bilirubin to albumin; implications for prevention of bilirubin encephalopathy in the newborn
    • Brodersen R 1979 Binding of bilirubin to albumin; implications for prevention of bilirubin encephalopathy in the newborn. CRC Crit Rev Clin Lab Sci 11:305-399
    • (1979) CRC Crit Rev Clin Lab Sci , vol.11 , pp. 305-399
    • Brodersen, R.1
  • 8
    • 0034653971 scopus 로고    scopus 로고
    • Measurement of plasma unbound unconjugated bilirubin
    • Ahlfors CE 2000 Measurement of plasma unbound unconjugated bilirubin. Anal Biochem 279:130-135
    • (2000) Anal Biochem , vol.279 , pp. 130-135
    • Ahlfors, C.E.1
  • 9
    • 0035839649 scopus 로고    scopus 로고
    • Affinity of human serum albumin for bilirubin varies with albumin concentration and buffer composition: Results of a novel ultrafiltration method
    • Weisiger RA, Ostrow JD, Koehler RK, Webster CC, Mukerjee P, Pascolo L, Tiribelli C 2001 Affinity of human serum albumin for bilirubin varies with albumin concentration and buffer composition: results of a novel ultrafiltration method. J Biol Chem 276:29953-29960.
    • (2001) J Biol Chem , vol.276 , pp. 29953-29960
    • Weisiger, R.A.1    Ostrow, J.D.2    Koehler, R.K.3    Webster, C.C.4    Mukerjee, P.5    Pascolo, L.6    Tiribelli, C.7
  • 10
    • 0002931546 scopus 로고
    • Aqueous solubility, albumin binding and tissue distribution of bilirubin
    • Ostrow JD (ed). Bile Marcel Dekker, New York
    • Brodersen R 1986 Aqueous solubility, albumin binding and tissue distribution of bilirubin. In: Ostrow JD (ed) Bile Pigments and Jaundice: Molecular, Metabolic and Medical Aspects. Marcel Dekker, New York, pp 157-181
    • (1986) Pigments and Jaundice: Molecular, Metabolic and Medical Aspects , pp. 157-181
    • Brodersen, R.1
  • 11
    • 0035075564 scopus 로고    scopus 로고
    • New concepts in bilirubin neurotoxicity and the need for studies at clinically relevant bilirubin concentrations
    • editorial
    • Ostrow JD, Tiribelli C 2001 New concepts in bilirubin neurotoxicity and the need for studies at clinically relevant bilirubin concentrations. [editorial] J Hepatology 34:467-470
    • (2001) J Hepatology , vol.34 , pp. 467-470
    • Ostrow, J.D.1    Tiribelli, C.2
  • 12
    • 0036234687 scopus 로고    scopus 로고
    • Mechanisms of bilirubin neurotoxicity
    • editorial
    • Ostrow JD, Pascolo L, Tiribelli C 2002 Mechanisms of bilirubin neurotoxicity. [editorial] Hepatology 35:1277-1280
    • (2002) Hepatology , vol.35 , pp. 1277-1280
    • Ostrow, J.D.1    Pascolo, L.2    Tiribelli, C.3
  • 13
    • 0014843909 scopus 로고
    • Factors influencing toxicity of bilirubin in cerebellum tissue culture
    • a. Silberberg DH, Johnson LH, Ritter L 1970 Factors influencing toxicity of bilirubin in cerebellum tissue culture. J Pediatr 77:386-396
    • (1970) J Pediatr , vol.77 , pp. 386-396
    • Silberberg, D.H.1    Johnson, L.H.2    Ritter, L.3
  • 14
    • 0014868202 scopus 로고
    • Effects of photodegradation products of bilirubin on myelinating cerebellum cultutres
    • b. Silberberg DH, Johnson LH, Schutta H, Ritter L 1970 Effects of photodegradation products of bilirubin on myelinating cerebellum cultutres. J Pediatr 77:613-618
    • (1970) J Pediatr , vol.77 , pp. 613-618
    • Silberberg, D.H.1    Johnson, L.H.2    Schutta, H.3    Ritter, L.4
  • 15
    • 0035066363 scopus 로고    scopus 로고
    • Bilirubin exerts additional toxic effects in hypoxic cultured neurons from the developing rat brain by the recruitment of glutamate neurotoxicity
    • Grojean S, Lievre V, Koziel V, Vert P, Daval JL 2001 Bilirubin exerts additional toxic effects in hypoxic cultured neurons from the developing rat brain by the recruitment of glutamate neurotoxicity. Pediatr Res 49:507-513
    • (2001) Pediatr Res , vol.49 , pp. 507-513
    • Grojean, S.1    Lievre, V.2    Koziel, V.3    Vert, P.4    Daval, J.L.5
  • 16
    • 0033669937 scopus 로고    scopus 로고
    • Bilirubin induces apoptosis via activation of NMDA receptors in developing rat brain neurons
    • Grojean S, Koziel V, Vert P, Daval JL 2000 Bilirubin induces apoptosis via activation of NMDA receptors in developing rat brain neurons. Exp Neurol 166:334-341
    • (2000) Exp Neurol , vol.166 , pp. 334-341
    • Grojean, S.1    Koziel, V.2    Vert, P.3    Daval, J.L.4
  • 17
    • 0027381418 scopus 로고
    • Competitive inhibition of thyroid hormone uptake into cultured rat brain astrocytes by bilirubin and bilirubin conjugates
    • Chantoux F, Chuniaud L, Dessante M, Trivin F, Blondeau JP, Francon J 1993 Competitive inhibition of thyroid hormone uptake into cultured rat brain astrocytes by bilirubin and bilirubin conjugates. Mol Cell Endocrinol 97:145-151
    • (1993) Mol Cell Endocrinol , vol.97 , pp. 145-151
    • Chantoux, F.1    Chuniaud, L.2    Dessante, M.3    Trivin, F.4    Blondeau, J.P.5    Francon, J.6
  • 18
    • 0027259153 scopus 로고
    • Age-dependent sensitivity of cultured rat glial cells to bilirubin toxicity
    • Amit Y, Brenner T 1993 Age-dependent sensitivity of cultured rat glial cells to bilirubin toxicity. Exp Neurol 121:248-255
    • (1993) Exp Neurol , vol.121 , pp. 248-255
    • Amit, Y.1    Brenner, T.2
  • 20
    • 33947451752 scopus 로고
    • Physical chemistry of protein solutions. IV. The combination of human serum albumin with chloride ion
    • Scatchard G, Scheinberg IH. Armstrong Jr SH 1950 Physical chemistry of protein solutions. IV. The combination of human serum albumin with chloride ion. J Am Chem Soc 72:535-540
    • (1950) J Am Chem Soc , vol.72 , pp. 535-540
    • Scatchard, G.1    Scheinberg, I.H.2    Armstrong S.H., Jr.3
  • 21
    • 0033547349 scopus 로고    scopus 로고
    • Inhibition of glutamate uptake by unconjugated bilirubin in cultured rat astrocytes: Role of concentration and pH
    • Silva RFM, Mata LR, Gulbenkian S, Brito A, Tiribelli C, Brites D 1999 Inhibition of glutamate uptake by unconjugated bilirubin in cultured rat astrocytes: role of concentration and pH. Biochem Biophys Res Commun 265:67-72
    • (1999) Biochem Biophys Res Commun , vol.265 , pp. 67-72
    • Silva, R.F.M.1    Mata, L.R.2    Gulbenkian, S.3    Brito, A.4    Tiribelli, C.5    Brites, D.6
  • 22
    • 0035072101 scopus 로고    scopus 로고
    • Bilirubin-induced apoptosis in cultured rat neural cells is aggravated by chenodeoxycholic acid but prevented by ursodeoxycholic acid
    • Silva RFM, Rodrigues CMP, Brites D 2001 Bilirubin-induced apoptosis in cultured rat neural cells is aggravated by chenodeoxycholic acid but prevented by ursodeoxycholic acid. J Hepatol 34:402-408
    • (2001) J Hepatol , vol.34 , pp. 402-408
    • Silva, R.F.M.1    Rodrigues, C.M.P.2    Brites, D.3
  • 23
    • 0036238782 scopus 로고    scopus 로고
    • Bilirubin induces apoptosis via the mitochondrial pathway in developing rat brain neurons
    • Rodrigues CMP, Sola S, Brites D 2002 Bilirubin induces apoptosis via the mitochondrial pathway in developing rat brain neurons. Hepatology 35:1186-1195
    • (2002) Hepatology , vol.35 , pp. 1186-1195
    • Rodrigues, C.M.P.1    Sola, S.2    Brites, D.3
  • 24
    • 0015394313 scopus 로고
    • The ready isomerization of bilirubin-IXα in aqueous solution
    • McDonagh AF, Assisi F 1972 The ready isomerization of bilirubin-IXα in aqueous solution. Biochem J 129:797-800
    • (1972) Biochem J , vol.129 , pp. 797-800
    • McDonagh, A.F.1    Assisi, F.2
  • 25
    • 0030607714 scopus 로고    scopus 로고
    • Cytotoxicity of bilirubin for human fibroblasts and rat astrocytes in culture. Effect of the ratio of bilirubin to serum albumin
    • Chuniaud L, Dessante M, Chantoux F, Blondeau JP, Francon J, Trivin F 1996 Cytotoxicity of bilirubin for human fibroblasts and rat astrocytes in culture. Effect of the ratio of bilirubin to serum albumin. Clin Chim Acta 256:103-114
    • (1996) Clin Chim Acta , vol.256 , pp. 103-114
    • Chuniaud, L.1    Dessante, M.2    Chantoux, F.3    Blondeau, J.P.4    Francon, J.5    Trivin, F.6
  • 27
    • 0033374730 scopus 로고    scopus 로고
    • Neuroprotective action of bilirubin against oxidative stress in primary hippocampal cultures
    • Dore S. Snyder SH 1999 Neuroprotective action of bilirubin against oxidative stress in primary hippocampal cultures. Ann NY Acad Sci 890:167-172
    • (1999) Ann NY Acad Sci , vol.890 , pp. 167-172
    • Dore, S.1    Snyder, S.H.2
  • 28
    • 0021955905 scopus 로고
    • Bilirubin toxicity in neural cell lines N115 and NBR10A
    • Schiff D, Chan G, Poznansky MJ 1985 Bilirubin toxicity in neural cell lines N115 and NBR10A. Pediatr Res 19:908-911
    • (1985) Pediatr Res , vol.19 , pp. 908-911
    • Schiff, D.1    Chan, G.2    Poznansky, M.J.3
  • 29
    • 0017164237 scopus 로고
    • Spectrophotometric characteristics of bilirubin
    • Lee KS, Gartner LM 1976 Spectrophotometric characteristics of bilirubin Pediatr Res 10:782-788
    • (1976) Pediatr Res , vol.10 , pp. 782-788
    • Lee, K.S.1    Gartner, L.M.2
  • 30
    • 0008956686 scopus 로고    scopus 로고
    • Maximum binding capacity of serum albumin for bilirubin is one, as revealed by circular dichroism
    • Siam M, Blaha G, Lehner H 1998 Maximum binding capacity of serum albumin for bilirubin is one, as revealed by circular dichroism. J Chem Soc Perkin Trans 11:853-856
    • (1998) J Chem Soc Perkin Trans , vol.11 , pp. 853-856
    • Siam, M.1    Blaha, G.2    Lehner, H.3
  • 32
    • 0026761329 scopus 로고
    • Ionization and self-association of unconjugated bilirubin, determined by rapid solvent partition from chloroform, with further studies of bilirubin solubility
    • Hahm JS, Ostrow JD, Mukerjee P, Celic L 1992 Ionization and self-association of unconjugated bilirubin, determined by rapid solvent partition from chloroform, with further studies of bilirubin solubility. J Lipid Res 33:1123-1137
    • (1992) J Lipid Res , vol.33 , pp. 1123-1137
    • Hahm, J.S.1    Ostrow, J.D.2    Mukerjee, P.3    Celic, L.4
  • 34
    • 0014108489 scopus 로고
    • Bilirubin encephalopathy in the Gunn rat: A fine structure study of the cerebellar cortex
    • Schutta HS, Johnson LH 1967 Bilirubin encephalopathy in the Gunn rat: a fine structure study of the cerebellar cortex. J Neuropathol Exp Neurol 26:377-396
    • (1967) J Neuropathol Exp Neurol , vol.26 , pp. 377-396
    • Schutta, H.S.1    Johnson, L.H.2
  • 35
    • 0027571990 scopus 로고
    • Cerebellar hypoplasia in the hyperbilirubinemic Gunn rat: Morphological aspects
    • Yamamura H, Takagishi Y 1993 Cerebellar hypoplasia in the hyperbilirubinemic Gunn rat: morphological aspects. Nagoya J Med Sci 55:11-21
    • (1993) Nagoya J Med Sci , vol.55 , pp. 11-21
    • Yamamura, H.1    Takagishi, Y.2
  • 36
    • 0030903507 scopus 로고    scopus 로고
    • Development of cerebellar hypoplasia in jaundiced Gunn rats: A quantitative light microscopic analysis
    • Conlee JW, Shapiro SM 1997 Development of cerebellar hypoplasia in jaundiced Gunn rats: a quantitative light microscopic analysis. Acta Neuropathol (Berl) 93:450-460
    • (1997) Acta Neuropathol (Berl) , vol.93 , pp. 450-460
    • Conlee, J.W.1    Shapiro, S.M.2
  • 37
    • 0034613310 scopus 로고    scopus 로고
    • Bilirubin does not modulate ionotropic glutamate receptors or glutamate transporters
    • Warr O, Mort D, Attwell D 2000 Bilirubin does not modulate ionotropic glutamate receptors or glutamate transporters. Brain Res 879:13-16
    • (2000) Brain Res , vol.879 , pp. 13-16
    • Warr, O.1    Mort, D.2    Attwell, D.3
  • 38
    • 0028110519 scopus 로고
    • Structure and binding of unconjugated bilirubin: Relevance for physiological and pathophysiological function
    • Ostrow JD, Mukerjee P, Tiribelli C 1994 Structure and binding of unconjugated bilirubin: relevance for physiological and pathophysiological function. J Lipid Res 35:1715-1737
    • (1994) J Lipid Res , vol.35 , pp. 1715-1737
    • Ostrow, J.D.1    Mukerjee, P.2    Tiribelli, C.3
  • 40
    • 0035655285 scopus 로고    scopus 로고
    • Localization of bilirubin in phospholipid bilayers by parallax analysis of fluorescence quenching
    • Zucker SD, Goessling W, Bootle EJ, Sterritt C 2001 Localization of bilirubin in phospholipid bilayers by parallax analysis of fluorescence quenching. J Lipid Res 42:1377-1388
    • (2001) J Lipid Res , vol.42 , pp. 1377-1388
    • Zucker, S.D.1    Goessling, W.2    Bootle, E.J.3    Sterritt, C.4
  • 41
    • 0034015283 scopus 로고    scopus 로고
    • Assessment of bilirubin toxicity to erythrocytes. Implication in neonatal jaundice management
    • Brito MA, Silva RFM, Tiribelli C, Brites D 2000 Assessment of bilirubin toxicity to erythrocytes. Implication in neonatal jaundice management. Eur J Clin Invest 30:239-247
    • (2000) Eur J Clin Invest , vol.30 , pp. 239-247
    • Brito, M.A.1    Silva, R.F.M.2    Tiribelli, C.3    Brites, D.4
  • 42
    • 0034902784 scopus 로고    scopus 로고
    • Benzyl alcohol, kernicterus, and unbound bilirubin
    • Ahlfors CE 2001 Benzyl alcohol, kernicterus, and unbound bilirubin. J Pediatr 139:317-319
    • (2001) J Pediatr , vol.139 , pp. 317-319
    • Ahlfors, C.E.1
  • 44
    • 0019433552 scopus 로고
    • Effect of serum dilution on apparent unbound bilirubin concentration as measured by the peroxidase method
    • Ahlfors CE 1981 Effect of serum dilution on apparent unbound bilirubin concentration as measured by the peroxidase method. Clin Chem 27:692-696
    • (1981) Clin Chem , vol.27 , pp. 692-696
    • Ahlfors, C.E.1
  • 45


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.