Antagonism between penicillin and erythromycin against Streptococcus pneumoniae: Does it exist?

Diagnostic Microbiology and Infectious Disease

Volumn 46, Issue 3, 2003, Pages 223-225

  Deshpande, Lalitagauri M ^a   Jones, Ronald N ^a,b  

^a JMI LABORATORIES   (United States)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROMYCIN; PENICILLIN G;

ARTICLE; BACTERICIDAL ACTIVITY; BACTERIUM ISOLATE; DRUG ANTAGONISM; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; STREPTOCOCCUS PNEUMONIA; STREPTOCOCCUS PNEUMONIAE;

EID: 0038642758     PISSN: 07328893     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0732-8893(03)00050-6     Document Type: Article

References (10)

1. Allen N.E., Epp J.K. Mechanism of penicillin-erythromycin synergy on antibiotic-resistant Staphylococcus aureus. Antimicrob Agents Chemother. 13:1978;849-853.
2. Cohn J.R., Jungkind D.L., Baker J.S. In vitro antagonism by erythromycin of the bactericidal action of antimicrobial agents against common respiratory pathogens. Antimicrob Agents Chemother. 18:1980;872-876.
3. Herrell W.E., Balows A., Becker J. Erythrocillin a new approach to the problem of antibiotic resistant staphylococci . Antibiot Med Clin Ther (NY). 7:1960;637-642.
4. How S.J., Hobson D., Hart C.A., Webster R.E. An in-vitro investigation of synergy and antagonism between antimicrobials against Chlymadia trachomatis. J Antimicrob Chemother. 15:1958;538.
5. Johansen H.K., Jensen T.G., Dessau R.B., Lundgren B., Fromodt-Moller N. Antagonism between penicillin and erythromycin against Streptococcus pneumoniae in vitro and in vivo. J Antimicrob Chemother. 46:2000;973-980.
6. Martinez J.A., Horcajada J.P., Almela H., Marco F., Soriano A., Garcia E., Marco M.A., Torres A., Mensa J. Addition of a macrolide to a β-lactam-based empirical antibiotic regimen is associated with lower in-hospital mortality for patients with bacteremic pneumococcal pneumonia. Clin Infect Dis. 36:2003;389-395.
7. National Committee for Clinical Laboratory Standards (2000). Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically, M7-A5. National Committee for Clinical Laboratory Standards, Wayne, PA.
8. National Committee for Clinical Laboratory Standards (2002). MIC testing. Supplemental tables M100-S12. National Committee for Clinical Laboratory, Standards Wayne, PA.
9. Penn R.L., Ward T.T., Steigbiegel R.T. Effects of erythromycin in combination with penicillin, ampicillin or gentamicin on the growth of Listeria monocytogenes. Antimicrob Agents Chemother. 22:1982;289-294.
10. ASM Manual of Clinical Microbiology (1992). Timed kill-curve method. Isenberg H. D. (ed), p 5.8, ASM Press, Washington, D.C.