Genomic structure and promoter activity of the testis haploid germ cell-specific intronless genes, Tact1 and Tact2

Molecular Reproduction and Development

Volumn 65, Issue 2, 2003, Pages 148-156

  Hisano, Mizue ^a   Yamada, Shuichi ^b   Tanaka, Hiromitsu ^a   Nishimune, Yoshitake ^a   Nozaki, Masami ^a  

^a OSAKA UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

Retroposition; Spermatid; Spermatogenesis; Transgenic mouse

Indexed keywords

ACTIN; COMPLEMENTARY DNA; GENOMIC DNA;

5' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CYCLIC AMP RESPONSIVE ELEMENT; EMBRYO; GENE; GENE EXPRESSION; GENE LIBRARY; GENE STRUCTURE; GENETIC CONSERVATION; GERM CELL; HAPLOIDY; INTRON; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; PROMOTER REGION; PSEUDOGENE; RETROPOSON; RNA SPLICING; RNA TRANSCRIPTION; RNA TRANSLATION; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SOUTHERN BLOTTING; SPERMATID; SPERMATOGENESIS; TACT1 GENE; TACT2 GENE; TESTIS; TRANSGENIC MOUSE;

ANIMALS; BASE SEQUENCE; CYCLIC AMP RESPONSE ELEMENT MODULATOR; CYTOSKELETAL PROTEINS; DNA-BINDING PROTEINS; HUMANS; MALE; MICE; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); PROTEINS; REPRESSOR PROTEINS; SPERMATIDS; SPERMATOGENESIS; TRANS-ACTIVATION (GENETICS);

MAMMALIA; MURINAE; MUS MUSCULUS; PRIMATES; RODENTIA;

EID: 0038641705     PISSN: 1040452X     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrd.10276     Document Type: Article

References (26)

1. Ashworth A, Skene B, Swift S, Lovell-Badge R. 1990. Zfa is an expressed retroposon derived from an alternative transcript of the Zfx gene. EMBO J 9:1529-1534.
2. Chadwick BP, Mull J, Helbling LA, Gill S, Leyne M, Robbins CM, Pinkett HW, Makalowska I, Maayan C, Blumenfeld A, Axelrod FB, Brownstein M, Gusella JF, Slaugenhaupt SA. 1999. Cloning, mapping, and expression of two novel actin genes, actin-like-7A (ACTL7A) and actin-like-7B (ACTL7B), from the familial dysautonomia candidate region on 9q31. Genomics 58:302-309.
3. Dahl HH, Brown RM, Hutchison WM, Maragos C, Brown GK. 1990. A testis-specific form of the human pyruvate dehydrogenase El alpha subunit is coded for by an intronless gene on chromosome 4. Genomics 8:225-232.
4. Esnault C, Maestre J, Heidmann T. 2000. Human LINE retrotransposons generate processed pseudogenes. Nat Genet 24:363-367.
5. Frankel S, Mooseker MS. 1996. The actin-related proteins. Curr Opin Cell Biol 8:30-37.
6. Fujii T, Tamura K, Masai K, Tanaka H, Nishimune Y, Nojima H. 2002. Use of stepwise subtraction to comprehensively isolate mouse genes whose transcription is up-regulated during spermiogenesis. EMBO Rep 3:367-372.
7. Galili N, Baldwin HS, Lund J, Reeves R, Gong W, Wang Z, Roe BA, Emanuel BS, Nayak S, Mickanin C, Budarf MI, Buck CA. 1997. A region of mouse chromosome 16 is syntenic to the DiGeorge, velocardiofacial syndrome minimal critical region. Genome Res 7:399.
8. Gellersen B, Kempf R, Sandhowe R, Weinbauer GF, Behr R. 2002. Novel leader exons of the cyclic adenosine 3′,5′-monophosphate response element modulator (CREM) gene, transcribed from promoters P3 and P4, are highly testis-specific in primates. Mol Hum Reprod 8:965-976.
9. Hecht N. 1986. Regulation of gene expression during mammalian spermatogenesis. In: Rossant I, Pedersen RA, editors. Experimental approaches to mammalian embryonic development. Cambridge: Cambridge University Press. pp 151-193.
10. Iannello RC, Gould JA, Young JC, Giudice A, Medcalf R, Kola I. 2000. Methylation-dependent silencing of the testis-specific Pdha-2 basal promoter occurs through selective targeting of an activating transcription factor/cAMP-responsive element-binding site. J Biol Chem 275:19603-19608.
11. Ikawa M, Yamada S, Nakanishi T, Okabe M. 1998. 'Green mice' and their potential usage in biological research. FEBS Lett 430:83-87.
12. Kessler SP, Rowe TM, Blendy JA, Erickson RP, Sen GC. 1998. A cyclic AMP response element in the angiotensin-converting enzyme gene and the transcription factor CREM are required for transcription of the mRNA for the testicular isozyme. J Biol Chem 273:9971-9975.
13. Kleene KC, Mulligan E, Steiger D, Donohue K, Mastrangelo MA. 1998. The mouse gene encoding the testis-specific isoform of Poly(A) binding protein (Pabp2) is an expressed retroposon: Intimations that gene expression in spermatogenic cells facilitates the creation of new genes. J Mol Evol 47:275-281.
14. McCarrey JR, Thomas K. 1987. Human testis-specific PGK gene lacks introns and possesses characteristics of a processed gene. Nature 326:501-505.
15. Mighell AJ, Smith NR, Robinson PA, Markham AF. 2000. Vertebrate pseudogenes. FEBS Lett 468:109-114.
16. Nozaki M, Mori M, Matsushiro A. 1994. The complete sequence of the gene encoding mouse cytokeratin 15. Gene 138:197-200.
17. Penttila TL, Yuan L, Mali P, Hoog C, Parvinen M. 1995. Haploid gene expression: Temporal onset and storage patterns of 13 novel transcripts during rat and mouse spermiogenesis. Biol Reprod 53:499-510.
18. Peter B, Man YM, Begg CE, Gall I, Leader DP. 1988. Mouse cytoskeletal gamma-actin: Analysis and implications of the structure of cloned cDNA and processed pseudogenes. J Mol Biol 203:665-675.
19. Reinton N, Haugen TB, Orstavik S, Skalhegg BS, Hansson V, Jahnsen T, Tasken K. 1998. The gene encoding the C gamma catalytic subunit of cAMP-dependent protein kinase is a transcribed retroposon. Genomics 49:290-297.
20. Sassone-Corsi P. 2002. Unique chromatin remodeling and transcriptional regulation in spermatogenesis. Science 296:2176-2178.
21. Sun Z, Means AR. 1995. An intron facilitates activation of the calspermin gene by the testis-specific transcription factor CREM tau. J Biol Chem 270:20962-20967.
22. Vanin EF. 1985. Processed pseudogenes: Characteristics and evolution. Annu Rev Genet 19:253-272.
23. Walker WH, Sanborn BM, Habener JF. 1994. An isoform of transcription factor CREM expressed during spermatogenesis lacks the phosphorylation domain and represses cAMP-induced transcription. Proc Natl Acad Sci USA 91:12423-12427.
24. Wolgemuth DJ, Watrin F. 1991. List ofcloned mouse genes with unique expression patterns during spermatogenesis. Mamm Genome 1:283-288.
25. Yoshimura Y, Tanaka H, Nozaki M, Yomogida K, Shimamura K, Yasunaga T, Nishimune Y. 1999. Genomic analysis ofmale germ cell specific actin capping protein alpha. Gene 237:193-199.
26. Yoshimura Y, Tanaka H, Nozaki M, Yomogida K, Yasunaga T, Nishimune Y. 2001. Nested genomic structure of haploid germ cell specific haspin gene. Gene 267:49-54.