Phenobarbital-imprinted overinduction of adult constituent CYP isoforms

Pharmacology

Volumn 68, Issue 4, 2003, Pages 204-215

  Agrawal, Arun K ^a   Shapiro, Bernard H ^a  

^a UNIVERSITY OF PENNSYLVANIA SCHOOL OF VETERINARY MEDICINE   (United States)

Author keywords

CAP3A1; Constitutive CYPs; CYP2C6; CYP2C7; CYP3A2; Cytochrome; P 450; Phenobarbital imprinting; Phenobarbital induction

Indexed keywords

ANTICONVULSIVE AGENT; CYTOCHROME P450; CYTOCHROME P450 2C; CYTOCHROME P450 2C11; CYTOCHROME P450 2C12; CYTOCHROME P450 3A1; CYTOCHROME P450 3A2; MESSENGER RNA; PHENOBARBITAL; PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DATA ANALYSIS; DNA TRANSCRIPTION; FEMALE; MALE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROVOCATION TEST; RAT; REGULATORY MECHANISM; SEX DIFFERENCE; STATISTICAL SIGNIFICANCE;

AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INDUCTION; FEMALE; ISOENZYMES; LIVER; MALE; PHENOBARBITAL; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SEX FACTORS; TIME FACTORS;

EID: 0038640814     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000070460     Document Type: Article

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