Localization of the ammonium transporters, Rh B glycoprotein and Rh C glycoprotein, in the mouse liver

Gastroenterology

Volumn 124, Issue 5, 2003, Pages 1432-1440

  Weiner, I David ^a,b   Miller, R Tyler ^c   Verlander, Jill W ^b  

^a N Florida S Georgia Vet Hlt Sys   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^c CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIA; CARRIER PROTEIN; GLUTAMATE AMMONIA LIGASE; GLYCOPROTEIN; MESSENGER RNA; RH B GLYCOPROTEIN; RH C GLYCOPROTEIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BILE DUCT; CENTRAL VEIN; FEMALE; GENE EXPRESSION; IMMUNOBLOTTING; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOHISTOCHEMISTRY; LIVER; LIVER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0038636372     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0016-5085(03)00277-4     Document Type: Article

References (39)

1. Haussinger D, Sies H, Gerok W. Functional hepatocyte heterogeneity in ammonia metabolism. The intercellular glutamine cycle. J Hepatol 1985;1:3-14.
2. Haussinger D, Lamers WH, Moorman AF. Hepatocyte heterogeneity in the metabolism of amino acids and ammonia. Enzyme 1992;46:72-93.
3. Dasarathy S, Mullen KD. Hepatic encephalopathy. Curr Treat Options Gastroenterol 2001;4:517-526,
4. Jones EA. Pathogenesis of hepatic encephalopathy. Clin Liver Dis 2000;4:467-485.
5. Albrecht J, Jones EA. Hepatic encephalopathy: molecular mechanisms underlying the clinical syndrome. J Neurol Sci 1999;170:138-146.
6. Gaasbeek Janzen JW, Moorman AF, Lamers WH, Charles R. Development of the heterogeneous distribution of carbamoylphosphate synthetase (ammonia) in rat-liver parenchyma during postnatal development. J Histochem Cytochem 1985;33:1205-1211.
7. Yagi Y, Saheki T, Imamura Y, Kobayashi K, Sase M, Nakano K, Matuo S, Inoue I, Hagihara S, Noda T. The heterogeneous distribution of argininosuccinate synthetase in the liver of type II citrullinemic patients. Its specificity and possible clinical implications. Am J Clin Pathol 1988;89:735-741.
8. Gebhardt R, Mecke D. Heterogeneous distribution of glutamine synthetase among rat liver parenchymal cells in situ and in primary culture. EMBO J 1983;2:567-570.
9. Gaasbeek Janzen JW, Gebhardt R, ten Voorde GH, Lamers WH, Charles R, Moorman AF. Heterogeneous distribution of glutamine synthetase during rat liver development. J Histochem Cytochem 1987;35:49-54.
10. Yip KP, Kurtz I. NH3 permeability of principal cells and intercalated cells measured by confocal fluorescence imaging. Am J Physiol 1995;269:F545-F550.
11. 3. Nature 1989;339:478-480.
12. Singh SK, Binder HJ, Geibel JP, Boron WF. An apical permeability barrier to NH3/NH4+ in isolated, perfused colonic crypts. Proc Natl Acad Sci U S A 1995;92:11573-11577.
13. Wall SM. Ammonium transport and the role of the Na,K-ATPase. Miner Electrolyte Metab 1996;22:311-317.
14. DuBose TD Jr, Good DW, Hamm LL, Wall SM. Ammonium transport in the kidney: new physiological concepts and their clinical implications. J Am Soc Nephrol 1991;1:1193-1203.
15. Avent ND. A new chapter in Rh research: Rh proteins are ammonium transporters. Trends Mol Med 2001;7:94-96.
16. Howitt SM, Udvardi MK. Structure, function and regulation of ammonium transporters in plants. Biochim Biophys Acta 2000;1465:152-170.
17. Heitman J, Agre P. A new face of the Rhesus antigen. Nat Genet 2000;26:258-259.
18. Marini AM, Soussi-Boudekou S, Vissers S, Andre B. A family of ammonium transporters in Saccharomyces cerevisiae. Mol Cell Biol 1997;17:4282-4293.
19. Huang CH, Liu PZ. New insights into the Rh superfamily of genes and proteins in erythroid ceils and nonerythroid tissues. Blood Cells Mol Dis 2001;27:90-101.
20. Liu Z, Peng J, Mo R, Hui Cc, Huang CH. Rh type B glycoprotein is a new member of the Rh superfamily and a putative ammonia transporter in mammals. J Biol Chem 2001;276:1424-1433.
21. Liu Z, Chen Y, Mo R, Hui CC, Cheng JF, Mohandas N, Huang CH. Characterization of human RhCG and mouse RhCG as novel nonerythroid Rh glycoprotein homologues predominantly expressed in kidney and testis. J Biol Chem 2000;275:25641-25651.
22. Westhoff CM, Ferreri-Jacobia M, Mak DD, Foskett JK. Identification of the erythrocyte Rh-blood group glycoprotein as a mammalian ammonium transporter. J Biol Chem 2002;277:12499-12502.
23. Marini AM, Matassi G, Raynal V, Andre B, Cartron JP, Cherif-Zahar B. The human Rhesus-associated RhAG protein and a kidney homologue promote ammonium transport in yeast. Nat Genet 2000;26:341-344.
24. Nakhoul NL, Palmer SA, Abdulnour-Nakhoul S, Hering-Smith K, Hamm LL. Ammonium transport in oocytes expressing Rhcg. FASEB J 2002;16:A53 (abstr).
25. Verlander JW, Miller RT, Frank AE, Royaux IE, Kim YH, Weiner ID. Localization of the ammonium transporter proteins, Rh B glycoprotein and Rh C glycoprotein, in the mouse kidney. AJP Renal 2002;284:F323-F337.
26. McLean IW, Nakane PK. Periodate-lysine-paraformaldehyde fixative. A new fixative for immunoelectron microscopy. J Histochem Cytochem 1974;22:1077-1083.
27. Bustin SA. Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays. J Mol Endocrinol 2000;25:169-193.
28. Liu Z, Huang CH. The mouse Rhl1 and Rhag genes: sequence, organization, expression, and chromosomal mapping. Biochem Genet 1999;37:119-138.
29. Haussinger D. Hepatocyte heterogeneity in glutamine and ammonia metabolism and the role of an intercellular glutamine cycle during ureogenesis in perfused rat liver. Eur J Biochem 1983;133:269-275.
30. Kaiser S, Gerok W, Haussinger D. Ammonia and glutamine metabolism in human liver slices: new aspects on the pathogenesis of hyperammonaemia in chronic liver disease. Eur J Clin Invest 1988;18:535-542.
31. Stoll B, McNelly S, Buscher HP, Haussinger D. Functional hepatocyte heterogeneity in glutamate, aspartate and alpha-ketoglutarate uptake: a histoautoradiographical study. Hepatology 1991;13:247-253.
32. Haussinger D, Stoll B, Stehle T, Gerok W. Hepatocyte heterogeneity in glutamate metabolism and bidirectional transport in perfused rat liver. Eur J Biochem 1989;185:189-195.
33. Stoll B, Hussinger D. Functional hepatocyte heterogeneity. Vascular 2-oxoglutarate is almost exclusively taken up by perivenous, glutamine-synthetase-containing hepatocytes. Eur J Biochem 1989;181:709-716.
34. Eladari D, Cheval L, Quentin F, Bertrand O, Mouro I, Cherif-Zahar B, Cartron JP, Paillard M, Doucet A, Chambrey R. Expression of RhCG, a new putative NH3/NH4+ transporter, along the rat nephron. J Am Soc Nephrol 2002;13:1999-2008.
35. Haagsma EB, Huizenga JR, Vonk RJ, Albers CJ, Grond J, Krom RA, Gips CH. Composition of bile after orthotopic liver transplantation. Scand J Gastroenterol 1987;22:1049-1055.
36. van der Linden W, Norman A. Composition of human hepatic bile. Acta Chir Scand 1967;133:307-313.
37. Marini AM, Andre B. In vivo N-glycosylation of the mep2 high-affinity ammonium transporter of Saccharomyces cerevisiae reveals an extracytosolic N-terminus. Mol Microbiol 2000;38:552-564.
38. Avent ND, Reid ME. The Rh blood group system: a review. Blood 2000;95:375-387.
39. Iwamoto S, Suganuma H, Kamesaki T, Omi T, Okuda H, Kajii E. Cloning and characterization of erythroid-specific DNase I-hypersensitive site in human rhesus-associated glycoprotein gene. J Biol Chem 2000;275:27324-27331.