Farnesyl protein transferase inhibitor ZARNESTRA R115777 - history of a discovery.

Current topics in medicinal chemistry

Volumn 3, Issue 10, 2003, Pages 1095-1102

  Venet, Marc ^a   End, David ^a   Angibaud, Patrick ^a  

^a JOHNSON AND JOHNSON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; ENZYME INHIBITOR; P21(RAS) FARNESYL PROTEIN TRANSFERASE; P21(RAS) FARNESYL-PROTEIN TRANSFERASE; QUINOLONE DERIVATIVE; TIPIFARNIB; TRANSFERASE;

ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; CLINICAL TRIAL; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; MOUSE; NEOPLASM; PROTEIN PROCESSING; REVIEW; STRUCTURE ACTIVITY RELATION;

ALKYL AND ARYL TRANSFERASES; ANIMALS; ANTINEOPLASTIC AGENTS; CLINICAL TRIALS; ENZYME INHIBITORS; HUMANS; MICE; MOLECULAR STRUCTURE; NEOPLASMS; PROTEIN ISOPRENYLATION; QUINOLONES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0038621230     PISSN: 15680266     EISSN: None     Source Type: Journal    
DOI: 10.2174/1568026033452050     Document Type: Review

References (22)