Aerosolized pentamidine prophylaxis against AIDS-related Pneumocystis carinii pneumonia and its short- and long-term effects on pulmonary function in the Japanese

Journal of Infection and Chemotherapy

Volumn 9, Issue 2, 2003, Pages 178-182

  Konishi, Mitsuru ^a   Yoshimoto, Eiichiro ^a   Takahashi, Ken ^a   Uno, Kenji ^a   Kasahara, Kei ^a   Murakawa, Koichi ^a   Maeda, Koichi ^a   Mikasa, Keiichi ^a   Narita, Nobuhiro ^b  

^a NARA MEDICAL UNIVERSITY   (Japan)

^b Nara Hospital   (Japan)

Author keywords

Aerosolized pentamidine; Human immunodeficiency virus infection; Pneumocystis carinii pneumonia; Prophylaxis failure; Pulmonary function

Indexed keywords

PENTAMIDINE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; AGED; ANTIBIOTIC PROPHYLAXIS; ARTICLE; ASIAN; CLINICAL ARTICLE; DRUG EFFECT; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; JAPAN; LUNG FUNCTION; LYMPHOCYTE COUNT; MALE; OXYGEN SATURATION; PNEUMOCYSTIS PNEUMONIA; PRIMARY PREVENTION; SECONDARY PREVENTION; T LYMPHOCYTE; THORAX RADIOGRAPHY; TREATMENT FAILURE; VITAL CAPACITY;

EID: 0038607744     PISSN: 1341321X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10156-003-0231-0     Document Type: Article

References (17)

1. Kaplan JE, Masur H, Holmes KK. Guidelines for preventing opportunistic infections among HIV-infected persons - 2002 Recommendations of the U.S. Public Health Service and the Infectious Diseases Society of America. MMWR (Recomm Rep) 2002;51:1-52.
2. Hardy WD, Feinberg J, Finkelstein DM, Power ME, He W, Kaczka C, et al. A controlled trial of trimethoprimsulfamethoxazole or aerosolized pentamidine for secondary prophylaxis of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome. N Engl J Med 1992;327:1842-8.
3. Pearson RD, Hewlett EL. Pentamidine for the treatment of Pneumocystis carinii pneumonia and other protozoal diseases. Ann Intern Med 1985;103:782-6.
4. Schneider MME, Hoepelman AIM, Schattenkerk JKME, Nielsen TL, Graaf YVD, Frissen JPHJ, et al. A controlled trial of aerosolized pentamidine of trimethoprim-sulfamethoxazole as primary prophylaxis against Pneumocystis carinii pneumonia in patients with human immunodeficiency virus infection. N Engl J Med 1992;327:1836-41.
5. Hirschel B, Lazzarin A, Chopard P, Opravil M, Furrer HJ, Rüttiman S, et al. A controlled study of inhaled pentamidine for primary prevention of Pneumocystis carinii pneumonia. N Engl J Med 1991;324:1079-83.
6. Ewig S, Schäfer H, Rockstroh JK, Pickenhain A, Luderitz B. Effect of long-term primary aerosolized pentamidine prophylaxis on breakthrough Pneumocystis carinii pneumonia. Eur Respir J 1996;9:1006-12.
7. Wei CCY, Gardner S, Rachlis A, Pack LL, Chan CKN. Risk factors for prophylaxis failure in patients receiving aerosol pentamidine for Pneumocystis carinii pneumonia prophylaxis. Chest 2001;119:1427-33.
8. Montaner JSG, Lawson LM, Gervais A, Hyland RH, Chan CK, Falutz JM, et al. Aerosol pentamidine for secondary prophylaxis of AIDS-related Pneumocystis carinii pneumonia: a randomized, placebo-controlled study. Ann Intern Med 1991;14:948-53.
9. Golden JA, Katz MH, Chernoff DN, Duncan SM, Conte JE Jr. A randomized comparison of once-monthly or twice-monthly highdose aerosolized pentamidine prophylaxis. Chest 1993;104:743-50.
10. Rizzardi GP, Lazzarin A, Musicco M, Frigerio D, Maillard M, Lucchini M, et al. Better efficacy of twice-monthly than monthly aerosolised pentamidine for secondary prophylaxis of Pneumocystis carinii pneumonia in patients with AIDS. An Italian multicentric randomised controlled trial. J Infect 1995;31:99-105.
11. Yamamoto H, Koizumi T, Miyahara T, Kaneki T, Kudo K. Serial pentamidine levels in bronchial epithelial lining fluid after aerosol administration. Respiration 2001;68:506-9.
12. Kennedy CA, Goetz MB. Atypical roentgenographic manifestation of Pneumocystis carinii pneumonia. Arch Intern Med 1992;152:1390-8.
13. Harrison KS, Laube BL. Bronchodilator pretreatment improves aerosol deposition uniformity in HIV-positive patients who cough while inhaling aerosolized pentamidine. Chest 1994;106:421-6.
14. Wei CCY, Pack LL, Chan CK. Effects of long-term aerosol pentamidine for Pneumocystis carinii prophylaxis on pulmonary function. Chest 1998;114:742-7.
15. Ong ELC, Dunbar EM, Mandal BK. Efficacy and effects on pulmonary function tests of weekly 600 mg aerosol pentamidine as prophylaxis against Pneumocystis carinii pneumonia. Infection 1992;10:136-9.
16. Camus F, Picciotto CD, Leprêtre A, Landman R, Girard PM. Pulmonary tolerance of prophylactic aerosolized pentamidine in human immunodeficiency virus-infected patients. Chest 1991;99:609-12.
17. Hiles RA, Mong S, Bekersky I, Banks C, Lulham G, Tellier P. Inhalation toxicity of aerosolized pentamidine isethionate in rats and dogs. Fundam Appl Toxicol 1994;23:382-90.