메뉴 건너뛰기




Volumn 41, Issue 7, 2003, Pages 682-693

Zona pellucida glycoproteins based immunocontraceptive vaccines: Strategies for development and their applications

Author keywords

Immunocontraception; Ovary; Recombinant proteins; Synthetic peptides; Zona pellucida glycoproteins

Indexed keywords

AMINO ACIDS; CELLS; DNA; IMMUNIZATION; PROTEINS;

EID: 0038607659     PISSN: 00195189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (2)

References (66)
  • 2
    • 0018822414 scopus 로고
    • Structure and function of the zona pellucida: Identification and characterization of the proteins of the mouse oocyte's zona pellucida
    • Bleil J D & Wassarman P M, Structure and function of the zona pellucida: identification and characterization of the proteins of the mouse oocyte's zona pellucida, Dev Biol, 76 (1980) 185.
    • (1980) Dev Biol , vol.76 , pp. 185
    • Bleil, J.D.1    Wassarman, P.M.2
  • 3
    • 0023886782 scopus 로고
    • Characterization of the human zona pellucida from fertilized and unfertilized eggs
    • Shabanowitz R B & O'Rand M G, Characterization of the human zona pellucida from fertilized and unfertilized eggs, J Reprod Fertil, 82 (1988) 151.
    • (1988) J Reprod Fertil , vol.82 , pp. 151
    • Shabanowitz, R.B.1    O'Rand, M.G.2
  • 4
    • 0031793814 scopus 로고    scopus 로고
    • Human zona pellucida glycoproteins: Characterization using antibodies against recombinant non-human primate ZP1, ZP2 and ZP3
    • Gupta S K, Yurewicz E C, Sacco A G, Kaul R, Jethanandani P & Govind C K, Human zona pellucida glycoproteins: characterization using antibodies against recombinant non-human primate ZP1, ZP2 and ZP3, Mol Hum Reprod 11 (1998) 1058.
    • (1998) Mol Hum Reprod , vol.11 , pp. 1058
    • Gupta, S.K.1    Yurewicz, E.C.2    Sacco, A.G.3    Kaul, R.4    Jethanandani, P.5    Govind, C.K.6
  • 5
    • 0028045713 scopus 로고
    • Cloning and characterization of zona pellucida genes and cDNA from a variety of mammalian species: The ZPA, ZPB AND ZPC gene families
    • Harris J D, Hibler D W, Fontenot G K, Hsu K T, Yurewicz E C & Sacco A G, Cloning and characterization of zona pellucida genes and cDNA from a variety of mammalian species: the ZPA, ZPB and ZPC gene families, DNA Sequence, 4 (1994) 361.
    • (1994) DNA Sequence , vol.4 , pp. 361
    • Harris, J.D.1    Hibler, D.W.2    Fontenot, G.K.3    Hsu, K.T.4    Yurewicz, E.C.5    Sacco, A.G.6
  • 6
    • 0027416199 scopus 로고
    • Conservation of mammalian secondary sperm receptor genes enables the promoter of the human gene to function in mouse oocytes
    • Liang L & Dean J, Conservation of mammalian secondary sperm receptor genes enables the promoter of the human gene to function in mouse oocytes, Dev Biol, 156 (1993) 399.
    • (1993) Dev Biol , vol.156 , pp. 399
    • Liang, L.1    Dean, J.2
  • 8
    • 0038131043 scopus 로고    scopus 로고
    • Comparative molecular biology and immunobiology of the zona pellucida glycoproteins: Fundamentals and applied aspects for contraception
    • Gupta S K, Srivastava N, Govind C K, Sivapurapu N & Gahlay G K, Comparative molecular biology and immunobiology of the zona pellucida glycoproteins: fundamentals and applied aspects for contraception, Proc Indian Natl Sci Acad-B, 66 (2000) 33.
    • (2000) Proc Indian Natl Sci Acad-B , vol.66 , pp. 33
    • Gupta, S.K.1    Srivastava, N.2    Govind, C.K.3    Sivapurapu, N.4    Gahlay, G.K.5
  • 9
    • 0028818844 scopus 로고
    • Mouse Zp1 encodes a zona pellucida protein homologous to egg envelope proteins in mammals and fish
    • Epifano O, Liang L & Dean J, Mouse Zp1 encodes a zona pellucida protein homologous to egg envelope proteins in mammals and fish, J Biol Chem, 270 (1995) 27254.
    • (1995) J Biol Chem , vol.270 , pp. 27254
    • Epifano, O.1    Liang, L.2    Dean, J.3
  • 10
    • 0036307181 scopus 로고    scopus 로고
    • The ZP domain is a conserved module for polymerization of extracellular proteins
    • Jovine L, Qi H, Williams Z, Litscher E & Wassarman P M, The ZP domain is a conserved module for polymerization of extracellular proteins, Nature Cell Biol,4 (2002) 457.
    • (2002) Nature Cell Biol , vol.4 , pp. 457
    • Jovine, L.1    Qi, H.2    Williams, Z.3    Litscher, E.4    Wassarman, P.M.5
  • 11
    • 0028895582 scopus 로고
    • Cloning of cDNAs for the precursor protein of a low-molecular weight subunit of the inner layer of the egg envelope (chorion) of the fish Oryzias latipes
    • Murata K, Sasaki T, Yasumasu S, Iuchi J, Enami J, Yasumasu I & Yamagani K, Cloning of cDNAs for the precursor protein of a low-molecular weight subunit of the inner layer of the egg envelope (chorion) of the fish Oryzias latipes, Dev Biol, 167 (1995) 9.
    • (1995) Dev Biol , vol.167 , pp. 9
    • Murata, K.1    Sasaki, T.2    Yasumasu, S.3    Iuchi, J.4    Enami, J.5    Yasumasu, I.6    Yamagani, K.7
  • 12
    • 0027493423 scopus 로고
    • Expression and structural analysis of a teleost homolog of a mammalian zona pellucida gene
    • Lyons C E, Payette K L, Price J L & Huang R C, Expression and structural analysis of a teleost homolog of a mammalian zona pellucida gene, J Biol Chem, 268 (1993) 21351.
    • (1993) J Biol Chem , vol.268 , pp. 21351
    • Lyons, C.E.1    Payette, K.L.2    Price, J.L.3    Huang, R.C.4
  • 13
    • 0030333348 scopus 로고    scopus 로고
    • Comparative structural and antigenic properties of zona pellucida glycoproteins
    • Hedrick J L, Comparative structural and antigenic properties of zona pellucida glycoproteins, J Reprod Fertil Suppl, 50 (1996) 9.
    • (1996) J Reprod Fertil Suppl , vol.50 , pp. 9
    • Hedrick, J.L.1
  • 14
    • 0343435291 scopus 로고
    • Galactose at the non-reducing terminus of O-linked oligosaccharides of mouse egg zona pellucida glycoprotein ZP3 is essential for the glycoprotein's sperm receptor activity
    • Bleil J D & Wassarman P M, Galactose at the non-reducing terminus of O-linked oligosaccharides of mouse egg zona pellucida glycoprotein ZP3 is essential for the glycoprotein's sperm receptor activity, Proc Natl Acad Sci USA, 85 (1988) 6778.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 6778
    • Bleil, J.D.1    Wassarman, P.M.2
  • 15
    • 0028048726 scopus 로고
    • Recombinant human zona pellucida protein ZP3 produced by Chinese hamster ovary cells induces the human sperm acrosome reaction and promotes sperm-egg fusion
    • van Duin M, Polman J E, de Breet I J, Ginneken K, Bunschoten H, Grootenhuis A, Brindle J & Aitken R J, Recombinant human zona pellucida protein ZP3 produced by Chinese hamster ovary cells induces the human sperm acrosome reaction and promotes sperm-egg fusion, Biol Reprod, 51 (1994) 607.
    • (1994) Biol Reprod , vol.51 , pp. 607
    • Van Duin, M.1    Polman, J.E.2    De Breet, I.J.3    Ginneken, K.4    Bunschoten, H.5    Grootenhuis, A.6    Brindle, J.7    Aitken, R.J.8
  • 16
    • 0023731968 scopus 로고
    • Identification of a secondary sperm receptor in the mouse egg zona pellucida: Role in maintenance of binding of acrosome-reacted sperm to eggs
    • Bleil J D, Greve J M & Wassarman P M, Identification of a secondary sperm receptor in the mouse egg zona pellucida: role in maintenance of binding of acrosome-reacted sperm to eggs, Dev Biol, 128 (1988) 376.
    • (1988) Dev Biol , vol.128 , pp. 376
    • Bleil, J.D.1    Greve, J.M.2    Wassarman, P.M.3
  • 17
    • 0024515399 scopus 로고
    • Characterization of a proteinase that cleaves zona pellucida glycoprotein ZP2 following activation of mouse egg
    • Moller C C & Wassarman P M, Characterization of a proteinase that cleaves zona pellucida glycoprotein ZP2 following activation of mouse egg, Dev Biol, 132 (1989) 103.
    • (1989) Dev Biol , vol.132 , pp. 103
    • Moller, C.C.1    Wassarman, P.M.2
  • 18
    • 0022429080 scopus 로고
    • Mouse egg extracellular coat is a matrix of interconnected filaments possessing a structural repeat
    • Greve J M & Wassarman P M, Mouse egg extracellular coat is a matrix of interconnected filaments possessing a structural repeat, J Mol Biol, 181 (1985) 253.
    • (1985) J Mol Biol , vol.181 , pp. 253
    • Greve, J.M.1    Wassarman, P.M.2
  • 19
    • 0032571326 scopus 로고    scopus 로고
    • Hetero-oligomerization-dependent binding of pig oocyte zona pellucida glycoproteins ZPB and ZPC to boar sperm membrane vesicles
    • Yurewicz E C, Sacco A G, Gupta S K, Xu N & Gage D A, Hetero-oligomerization-dependent binding of pig oocyte zona pellucida glycoproteins ZPB and ZPC to boar sperm membrane vesicles, J Biol Chem 273 (1998) 7488.
    • (1998) J Biol Chem , vol.273 , pp. 7488
    • Yurewicz, E.C.1    Sacco, A.G.2    Gupta, S.K.3    Xu, N.4    Gage, D.A.5
  • 20
    • 0029892411 scopus 로고    scopus 로고
    • Evaluating zona pellucida structure and function using antibodies to rabbit 55 kDa ZP protein expressed in baculovirus expression system
    • Prasad S V, Wilkins B, Skinner S M & Dunbar B S, Evaluating zona pellucida structure and function using antibodies to rabbit 55 kDa ZP protein expressed in baculovirus expression system, Mol Reprod Dev, 43 (1996) 519.
    • (1996) Mol Reprod Dev , vol.43 , pp. 519
    • Prasad, S.V.1    Wilkins, B.2    Skinner, S.M.3    Dunbar, B.S.4
  • 21
    • 0028909347 scopus 로고
    • Expresssion of the rabbit sperm protein Sp17 in COS cells and interaction of recombinant Sp17 with the rabbit zona pellucida
    • Yamasaki N, Richardson R T & O'Rand M C, Expresssion of the rabbit sperm protein Sp17 in COS cells and interaction of recombinant Sp17 with the rabbit zona pellucida, Mol Reprod Dev, 40 (1995) 48.
    • (1995) Mol Reprod Dev , vol.40 , pp. 48
    • Yamasaki, N.1    Richardson, R.T.2    O'Rand, M.C.3
  • 22
    • 0035084331 scopus 로고    scopus 로고
    • Purified and refolded recombinant bonnet monkey (Macaca radiata) zona pellucida glycoprotein-B expressed in Escherichia coli binds to spermatozoa
    • Govind C K, Gahlay G K, Choudhury S & Gupta S K, Purified and refolded recombinant bonnet monkey (Macaca radiata) zona pellucida glycoprotein-B expressed in Escherichia coli binds to spermatozoa, Biol Reprod, 64 (2001) 1147.
    • (2001) Biol Reprod , vol.64 , pp. 1147
    • Govind, C.K.1    Gahlay, G.K.2    Choudhury, S.3    Gupta, S.K.4
  • 23
    • 0017705178 scopus 로고
    • Immunization of mice with heat solubilized hamster zonae: Production of antizona antibody and inhibition of fertility
    • Gwatkin R B, Williams D T & Carlo D J, Immunization of mice with heat solubilized hamster zonae: production of antizona antibody and inhibition of fertility, Fertil Steril, 28 (1977) 871.
    • (1977) Fertil Steril , vol.28 , pp. 871
    • Gwatkin, R.B.1    Williams, D.T.2    Carlo, D.J.3
  • 24
    • 0019859862 scopus 로고
    • Effect of alloimmunization and heteroimmunization with zonae pelluicidae on fertility in rabbits
    • Wood D M, Liu C & Dunbar B S, Effect of alloimmunization and heteroimmunization with zonae pelluicidae on fertility in rabbits, Biol Reprod, 25 (1981) 439.
    • (1981) Biol Reprod , vol.25 , pp. 439
    • Wood, D.M.1    Liu, C.2    Dunbar, B.S.3
  • 25
    • 0021752420 scopus 로고
    • Immunization with zona pellucida proteins results in abnormal ovarian follicular differentiation and inhibition of gonadotrophin-induced steroid secretion
    • Skinner S M, Mills T, Kirchick H J & Dunbar B S, Immunization with zona pellucida proteins results in abnormal ovarian follicular differentiation and inhibition of gonadotrophin-induced steroid secretion, Endocrinology, 115 (1984) 2418.
    • (1984) Endocrinology , vol.115 , pp. 2418
    • Skinner, S.M.1    Mills, T.2    Kirchick, H.J.3    Dunbar, B.S.4
  • 26
    • 0020487543 scopus 로고
    • Infertility in bitches induced by active immunization with porcine zonae pellucidae
    • Mahi-Brown C A, Huang T T Jr, & Yanagimachi R, Infertility in bitches induced by active immunization with porcine zonae pellucidae, J Exp Zool, 222 (1982) 89.
    • (1982) J Exp Zool , vol.222 , pp. 89
    • Mahi-Brown, C.A.1    Huang T.T., Jr.2    Yanagimachi, R.3
  • 27
    • 0020990558 scopus 로고
    • Response of monkeys to porcine zona pellucida as detected by a solid phase radio-immunoassay
    • Gulyas B J, Yuan L C, Gwatkin R B & Schmell E D, Response of monkeys to porcine zona pellucida as detected by a solid phase radio-immunoassay, J Med Primatol, 12 (1983) 331.
    • (1983) J Med Primatol , vol.12 , pp. 331
    • Gulyas, B.J.1    Yuan, L.C.2    Gwatkin, R.B.3    Schmell, E.D.4
  • 28
    • 0023186492 scopus 로고
    • Ovaries remain functional in squirrel monkeys (Saimiri sciureus) immunized with porcine zona pellucida 55,000 macromolecule
    • Sacco A G, Pierce D L, Subramanian M G, Yurewicz E C & Dukelow W R, Ovaries remain functional in squirrel monkeys (Saimiri sciureus) immunized with porcine zona pellucida 55,000 macromolecule, Biol Reprod, 36 (1987) 481.
    • (1987) Biol Reprod , vol.36 , pp. 481
    • Sacco, A.G.1    Pierce, D.L.2    Subramanian, M.G.3    Yurewicz, E.C.4    Dukelow, W.R.5
  • 29
    • 0027944732 scopus 로고
    • Antifertility effects of porcine zona pellucida-3 immunization using permissible adjuvants in female bonnet monkeys (Macaca radiata): Reversibility, effect on follicular development and hormonal profiles
    • Bagavant H, Thillai-Koothan P, Sharma M G, Talwar G P & Gupta S K, Antifertility effects of porcine zona pellucida-3 immunization using permissible adjuvants in female bonnet monkeys (Macaca radiata): reversibility, effect on follicular development and hormonal profiles, J Reprod Fertil, 102 (1994) 17.
    • (1994) J Reprod Fertil , vol.102 , pp. 17
    • Bagavant, H.1    Thillai-Koothan, P.2    Sharma, M.G.3    Talwar, G.P.4    Gupta, S.K.5
  • 30
    • 0024829936 scopus 로고
    • Role of adjuvants in inhibitory influence of immunization with porcine zona pellucida antigen (ZP3) on ovarian folliculogenesis in bonnet monkeys: A morphological study
    • Upadhyay S N, Thillai-koothan P, Bamezai A, Jayaraman S & Talwar G P, Role of adjuvants in inhibitory influence of immunization with porcine zona pellucida antigen (ZP3) on ovarian folliculogenesis in bonnet monkeys: a morphological study, Biol Reprod, 41 (1989) 665.
    • (1989) Biol Reprod , vol.41 , pp. 665
    • Upadhyay, S.N.1    Thillai-Koothan, P.2    Bamezai, A.3    Jayaraman, S.4    Talwar, G.P.5
  • 31
    • 0024803442 scopus 로고
    • Effect of varying dosage and adjuvants on antibody response in squirrel monkeys (Saimiri sciureus) immunized with the porcine zona pellucida Mr = 55,000 glycoprotein (ZP3)
    • Sacco A G, Yurewicz E C & Subramanian M G, Effect of varying dosage and adjuvants on antibody response in squirrel monkeys (Saimiri sciureus) immunized with the porcine zona pellucida Mr = 55,000 glycoprotein (ZP3), Am J Reprod Immunol, 21 (1989) 1.
    • (1989) Am J Reprod Immunol , vol.21 , pp. 1
    • Sacco, A.G.1    Yurewicz, E.C.2    Subramanian, M.G.3
  • 32
    • 0022362144 scopus 로고
    • Fertility control in the bitch by active immunization with porcine zonae pellucidae: Use of different adjuvants and patterns of estradiol and progesterone levels in estrous cycles
    • Mahi-Brown C A, Yanagimachi R, Hoffman J C & Huang TT Jr, Fertility control in the bitch by active immunization with porcine zonae pellucidae: use of different adjuvants and patterns of estradiol and progesterone levels in estrous cycles, Biol Reprod, 32 (1985) 761.
    • (1985) Biol Reprod , vol.32 , pp. 761
    • Mahi-Brown, C.A.1    Yanagimachi, R.2    Hoffman, J.C.3    Huang T.T., Jr.4
  • 33
    • 0031853969 scopus 로고    scopus 로고
    • Evaluation of contraceptive potential of recombinant human ZP3 peptides in a primate model: Their safety and efficacy
    • Paterson M, Wilson M R, Morris K D, van Duin M & Aitken R J, Evaluation of contraceptive potential of recombinant human ZP3 peptides in a primate model: their safety and efficacy, Am J Reprod Imunol, 40 (1998) 198.
    • (1998) Am J Reprod Imunol , vol.40 , pp. 198
    • Paterson, M.1    Wilson, M.R.2    Morris, K.D.3    Van Duin, M.4    Aitken, R.J.5
  • 34
    • 0032809079 scopus 로고    scopus 로고
    • Infertility in female rabbits (Oryctolagus cuniculus) alloimmunized with the rabbit zona pellucida protein ZPB either as a purified recombinant protein or expressed by recombinant myxoma virus
    • Kerr P J, Jackson R J, Robinson A J, Swan J, Silvers L, French N, Clarke H, Hall D F & Holland M K, Infertility in female rabbits (Oryctolagus cuniculus) alloimmunized with the rabbit zona pellucida protein ZPB either as a purified recombinant protein or expressed by recombinant myxoma virus, Biol Reprod, 61 (1999) 606.
    • (1999) Biol Reprod , vol.61 , pp. 606
    • Kerr, P.J.1    Jackson, R.J.2    Robinson, A.J.3    Swan, J.4    Silvers, L.5    French, N.6    Clarke, H.7    Hall, D.F.8    Holland, M.K.9
  • 35
    • 0033833699 scopus 로고    scopus 로고
    • Effectiveness of zona pellucida protein ZPB as an immunocontraceptive antigen
    • Martinez M L & Harris J D, Effectiveness of zona pellucida protein ZPB as an immunocontraceptive antigen, J Reprod Fertil, 120 (2000) 19.
    • (2000) J Reprod Fertil , vol.120 , pp. 19
    • Martinez, M.L.1    Harris, J.D.2
  • 36
    • 0034237157 scopus 로고    scopus 로고
    • Failure of female baboons (Papio anubis) to conceive following immunization with recombinant non-human primate zona pellucida glycoprotein-B expressed in Escherichia coli
    • Govind C K & Gupta S K, Failure of female baboons (Papio anubis) to conceive following immunization with recombinant non-human primate zona pellucida glycoprotein-B expressed in Escherichia coli, Vaccine, 18 (2000) 2970.
    • (2000) Vaccine , vol.18 , pp. 2970
    • Govind, C.K.1    Gupta, S.K.2
  • 37
    • 0037159616 scopus 로고    scopus 로고
    • Evaluation of the immunocontraceptive potential of Escherichia coli expressed recombinant non-human primate zona pellucida glycoproteins in a homologous animal model
    • Govind C K, Srivastava N & Gupta S K, Evaluation of the immunocontraceptive potential of Escherichia coli expressed recombinant non-human primate zona pellucida glycoproteins in a homologous animal model, Vaccine, 21 (2002) 78.
    • (2002) Vaccine , vol.21 , pp. 78
    • Govind, C.K.1    Srivastava, N.2    Gupta, S.K.3
  • 38
    • 0037154821 scopus 로고    scopus 로고
    • Analysis of recombinant mouse zona pellucida protein-2 (ZP-2) constructs for immunocontraception
    • Lea I A, Widgreen E E & O'Rand M G, Analysis of recombinant mouse zona pellucida protein-2 (ZP-2) constructs for immunocontraception, Vaccine, 20 (2002) 1515.
    • (2002) Vaccine , vol.20 , pp. 1515
    • Lea, I.A.1    Widgreen, E.E.2    O'Rand, M.G.3
  • 39
    • 0031029515 scopus 로고    scopus 로고
    • Antibody responses and infertility in mice following oral immunization with attenuated Salmonella typhimurium expressing recombinant murine ZP3
    • rd, Antibody responses and infertility in mice following oral immunization with attenuated Salmonella typhimurium expressing recombinant murine ZP3, Biol Reprod, 56 (1997) 33.
    • (1997) Biol Reprod , vol.56 , pp. 33
    • Zhang, X.1    Lou, Y.H.2    Koopman, M.3    Doggett, T.4    Tung, K.S.5    Curtiss R. III6
  • 40
    • 0031973545 scopus 로고    scopus 로고
    • Infertility in mice induced by a recombinant ectomelia virus expressing mouse zona pellucida glycoprotein-3
    • Jackson R J, Maguire D J, Hinds L A & Ramshaw I A, Infertility in mice induced by a recombinant ectomelia virus expressing mouse zona pellucida glycoprotein-3, Biol Reprod, 58 (1998) 152.
    • (1998) Biol Reprod , vol.58 , pp. 152
    • Jackson, R.J.1    Maguire, D.J.2    Hinds, L.A.3    Ramshaw, I.A.4
  • 42
    • 0032747388 scopus 로고    scopus 로고
    • DNA and RNA-based vaccines: Principles, progress and prospects
    • Leitner W W, Ying H & Restifo N P, DNA and RNA-based vaccines: principles, progress and prospects, Vaccine, 18 (2000) 765.
    • (2000) Vaccine , vol.18 , pp. 765
    • Leitner, W.W.1    Ying, H.2    Restifo, N.P.3
  • 43
    • 0027369829 scopus 로고
    • DNA based immunization for hepatitis B induces continuous secretion of antigen and high level of circulating antibody
    • Davis H L, Michel M L & Whalen R G, DNA based immunization for hepatitis B induces continuous secretion of antigen and high level of circulating antibody, Hum Mol Genet, 2 (1993) 1847.
    • (1993) Hum Mol Genet , vol.2 , pp. 1847
    • Davis, H.L.1    Michel, M.L.2    Whalen, R.G.3
  • 44
    • 0036019140 scopus 로고    scopus 로고
    • Antibodies generated in response to plasmid DNA encoding zona pellucida glycoprotein-B inhibit in vitro human sperm-egg binding
    • Rath A, Choudhary S, Hasegawa A, Koyama K & Gupta S K, Antibodies generated in response to plasmid DNA encoding zona pellucida glycoprotein-B inhibit in vitro human sperm-egg binding, Mol Rep Dev, 62 (2002) 525.
    • (2002) Mol Rep Dev , vol.62 , pp. 525
    • Rath, A.1    Choudhary, S.2    Hasegawa, A.3    Koyama, K.4    Gupta, S.K.5
  • 45
    • 0037449098 scopus 로고    scopus 로고
    • Characterization of immune response in mice to plasmid DNA encoding dog zona pellucida glycoprotein-3
    • Rath A, Batra D, Kaur R, Vrati S & Gupta S K, Characterization of immune response in mice to plasmid DNA encoding dog zona pellucida glycoprotein-3, Vaccine, 21 (2003) 1913.
    • (2003) Vaccine , vol.21 , pp. 1913
    • Rath, A.1    Batra, D.2    Kaur, R.3    Vrati, S.4    Gupta, S.K.5
  • 48
    • 0034332736 scopus 로고    scopus 로고
    • Immunocontraception of white-tailed deer using native and recombinant zona pellucida vaccines
    • Miller L A, Johns B E & Killian G J, Immunocontraception of white-tailed deer using native and recombinant zona pellucida vaccines, Anim Reprod Sci, 63 (2000) 187.
    • (2000) Anim Reprod Sci , vol.63 , pp. 187
    • Miller, L.A.1    Johns, B.E.2    Killian, G.J.3
  • 51
    • 0036075521 scopus 로고    scopus 로고
    • Evaluation of the immunocontraceptive potential of Escherichia coli expressed recombinant dog ZP2 and ZP3 in a homologous animal model
    • Srivastava N, Santhanam R, Sheela P, Mukund S, Thakral S S, Malik B S & Gupta S K, Evaluation of the immunocontraceptive potential of Escherichia coli expressed recombinant dog ZP2 and ZP3 in a homologous animal model, Reproduction, 123 (2002) 847.
    • (2002) Reproduction , vol.123 , pp. 847
    • Srivastava, N.1    Santhanam, R.2    Sheela, P.3    Mukund, S.4    Thakral, S.S.5    Malik, B.S.6    Gupta, S.K.7
  • 52
    • 0027360819 scopus 로고
    • Antigen mimicry in autoimmune disease-sharing of amino acid residues critical for pathogenic T cell activation
    • Luo A M, Garza K M, Hunt D & Tung K S, Antigen mimicry in autoimmune disease-sharing of amino acid residues critical for pathogenic T cell activation, J Clin Invest, 92 (1993) 2117.
    • (1993) J Clin Invest , vol.92 , pp. 2117
    • Luo, A.M.1    Garza, K.M.2    Hunt, D.3    Tung, K.S.4
  • 53
    • 0029051909 scopus 로고
    • A zona pellucida-3 peptide vaccine induces antibodies and reversible infertility without ovarian pathology
    • Iou Y, Ang J, Thai H, McElveen F & Tung KS, A zona pellucida-3 peptide vaccine induces antibodies and reversible infertility without ovarian pathology, J Immunol, 155 (1995) 2715.
    • (1995) J Immunol , vol.155 , pp. 2715
    • Iou, Y.1    Ang, J.2    Thai, H.3    McElveen, F.4    Tung, K.S.5
  • 54
    • 0031045375 scopus 로고    scopus 로고
    • Immunogenicity and contraceptive potential of a human zona pellucida-3 peptide vaccine
    • Bagavant H, Fusi F M, Baisch J, Kurth B, David C S & Tung K S, Immunogenicity and contraceptive potential of a human zona pellucida-3 peptide vaccine, Biol Reprod, 56 (1997) 764.
    • (1997) Biol Reprod , vol.56 , pp. 764
    • Bagavant, H.1    Fusi, F.M.2    Baisch, J.3    Kurth, B.4    David, C.S.5    Tung, K.S.6
  • 55
    • 0036306176 scopus 로고    scopus 로고
    • Native zona pellucida reactivity and in vitro effect on human sperm-egg binding with antisera against bonnet monkey ZP1 and ZP3 synthetic peptides
    • Sivapurapu N, Upadhyay A, Hasegawa A, Koyama K & Gupta S K, Native zona pellucida reactivity and in vitro effect on human sperm-egg binding with antisera against bonnet monkey ZP1 and ZP3 synthetic peptides, J Reprod Immunol, 56 (2002) 77.
    • (2002) J Reprod Immunol , vol.56 , pp. 77
    • Sivapurapu, N.1    Upadhyay, A.2    Hasegawa, A.3    Koyama, K.4    Gupta, S.K.5
  • 57
    • 0002502214 scopus 로고    scopus 로고
    • Immunocontraceptive potential of recombinant bonnet monkey (Macaca radiata) zona pellucida glycoprotein-C expressed in Escherichia coli and its corresponding synthetic peptide
    • Kaul R, Sivapurapu N, Afzalpurkar A, Srikanth V, Govind C K & Gupta S K, Immunocontraceptive potential of recombinant bonnet monkey (Macaca radiata) zona pellucida glycoprotein-C expressed in Escherichia coli and its corresponding synthetic peptide, Reprod BioMed Online, 2 (2001) 33.
    • (2001) Reprod BioMed Online , vol.2 , pp. 33
    • Kaul, R.1    Sivapurapu, N.2    Afzalpurkar, A.3    Srikanth, V.4    Govind, C.K.5    Gupta, S.K.6
  • 58
    • 0030902753 scopus 로고    scopus 로고
    • Induction of native protein reactive antibodies by immunization with peptides containing linear B cell epitopes defined by anti-porcine ZP3β monoclonal antibodies
    • Afzalpurkar A, Sacco A G, Yurewicz E C & Gupta S K, Induction of native protein reactive antibodies by immunization with peptides containing linear B cell epitopes defined by anti-porcine ZP3β monoclonal antibodies, J Reprod Immunol, 33 (1997) 113.
    • (1997) J Reprod Immunol , vol.33 , pp. 113
    • Afzalpurkar, A.1    Sacco, A.G.2    Yurewicz, E.C.3    Gupta, S.K.4
  • 59
    • 0031435375 scopus 로고    scopus 로고
    • Immunoreactivity and in vitro effect on human sperm-egg binding of antibodies against peptides corresponding to bonnet monkey zona pellucida-3 glycoprotein
    • Afzalpurkar A, Shibahara H, Hasegawa A, Koyama K & Gupta S K, Immunoreactivity and in vitro effect on human sperm-egg binding of antibodies against peptides corresponding to bonnet monkey zona pellucida-3 glycoprotein, Hum Reprod, 12 (1997) 2664.
    • (1997) Hum Reprod , vol.12 , pp. 2664
    • Afzalpurkar, A.1    Shibahara, H.2    Hasegawa, A.3    Koyama, K.4    Gupta, S.K.5
  • 60
    • 0038350927 scopus 로고    scopus 로고
    • Efficacy of antibodies against Escherichia coli expressed chimeric recombinant protein encompassing multiple epitopes of zona pellucida glycoproteins to inhibit in vitro human sperm-egg binding
    • In Press
    • Sivapurapu N, Upadhyay A, Hasegawa A, Koyama K & Gupta S K, Efficacy of antibodies against Escherichia coli expressed chimeric recombinant protein encompassing multiple epitopes of zona pellucida glycoproteins to inhibit in vitro human sperm-egg binding, Mol Reprod Dev (In Press).
    • Mol Reprod Dev
    • Sivapurapu, N.1    Upadhyay, A.2    Hasegawa, A.3    Koyama, K.4    Gupta, S.K.5
  • 62
    • 0344527804 scopus 로고    scopus 로고
    • Evaluation of ZP2 domains of functional importance with antisera against synthetic ZP2 peptides
    • Hinsch E, Hagele W, Bohle R M, Schill W B & Hinsch K D, Evaluation of ZP2 domains of functional importance with antisera against synthetic ZP2 peptides, J Reprod Fertil, 114 (1998) 245.
    • (1998) J Reprod Fertil , vol.114 , pp. 245
    • Hinsch, E.1    Hagele, W.2    Bohle, R.M.3    Schill, W.B.4    Hinsch, K.D.5
  • 63
    • 0344457340 scopus 로고    scopus 로고
    • A contraceptive peptide vaccine targeting sulfated glycoprotein ZP2 of the mouse zona pellucida
    • Sun W, Lou Y H, Dean J & Tung K S K, A contraceptive peptide vaccine targeting sulfated glycoprotein ZP2 of the mouse zona pellucida, Biol Reprod, 60 (1999) 900.
    • (1999) Biol Reprod , vol.60 , pp. 900
    • Sun, W.1    Lou, Y.H.2    Dean, J.3    Tung, K.S.K.4
  • 64
    • 0033889612 scopus 로고    scopus 로고
    • Analysis of B cell epitopes of a glycoprotein porcine zona pellucida (pZP1)
    • Shigeta M, Hasegawa A, Hamada Y & Koyama K, Analysis of B cell epitopes of a glycoprotein porcine zona pellucida (pZP1), J Reprod Immunol, 47 (2000) 159.
    • (2000) J Reprod Immunol , vol.47 , pp. 159
    • Shigeta, M.1    Hasegawa, A.2    Hamada, Y.3    Koyama, K.4
  • 65
    • 0036271827 scopus 로고    scopus 로고
    • Contraceptive potential of synthetic peptides of zona pellucida protein (ZPA)
    • Hasegawa A, Hamada Y, Shigeta M & Koyama K, Contraceptive potential of synthetic peptides of zona pellucida protein (ZPA), J Reprod Immunol, 53 (2002) 91.
    • (2002) J Reprod Immunol , vol.53 , pp. 91
    • Hasegawa, A.1    Hamada, Y.2    Shigeta, M.3    Koyama, K.4
  • 66
    • 0033970760 scopus 로고    scopus 로고
    • Delineation of a conserved B cell epitope on bonnet monkey (Macaca radiata) and human zona pellucida glycoprotein-B by monoclonal antibodies demonstrating inhibition of sperm-egg binding
    • Govind C K, Hasegawa A, Koyama K & Gupta S K, Delineation of a conserved B cell epitope on bonnet monkey (Macaca radiata) and human zona pellucida glycoprotein-B by monoclonal antibodies demonstrating inhibition of sperm-egg binding, Biol Reprod, 62 (2000) 67.
    • (2000) Biol Reprod , vol.62 , pp. 67
    • Govind, C.K.1    Hasegawa, A.2    Koyama, K.3    Gupta, S.K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.