The effect of mannose-binding protein gene polymorphisms in recurrent respiratory system infections in children and lung tuberculosis

Turkish Journal of Pediatrics

Volumn 45, Issue 2, 2003, Pages 95-99

  Özbaş Gerçeker, Filiz ^a   Tezcan, Ilhan ^b   Berkel, A Izzet ^b   Özkara, Şeref ^c   Özcan, Ayşenaz ^c   Ersoy, Fügen ^b   Sanal, Özden ^b   Özgüç, Meral ^a,b  

^a SCIENTIFIC AND TECHNOLOGICAL RESEARCH COUNCIL OF TURKEY   (Turkey)

^b HACETTEPE UNIVERSITY   (Turkey)

^c Ataturk Chest Disease and Thoracic Surgery Hospital   (Turkey)

Author keywords

Mannose binding lectin; Recurrent respiratory system infections; Tuberculosis

Indexed keywords

LECTIN; MANNOSE BINDING PROTEIN;

ADULT; ALLELE; ARTICLE; CODON; CONTROLLED STUDY; DNA POLYMORPHISM; EXON; GENE FREQUENCY; GENE MUTATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; INFANT; LUNG TUBERCULOSIS; MAJOR CLINICAL STUDY; OTITIS MEDIA; PATHOGENESIS; POPULATION RESEARCH; PRESCHOOL CHILD; RECURRENT INFECTION; RESPIRATORY TRACT INFECTION; STRUCTURAL GENE; TURKEY (REPUBLIC);

ADULT; BACTERIAL INFECTIONS; CHILD, PRESCHOOL; CODON; EXONS; GENE EXPRESSION; HUMANS; INFANT; MANNOSE-BINDING LECTIN; POLYMORPHISM, GENETIC; RECURRENCE; RESPIRATORY TRACT INFECTIONS; TUBERCULOSIS;

EID: 0038601730     PISSN: 00414301     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Garred P, Brygge K, Sorensen CH, Madsen HO, Thiel S, Svejgaard A. Mannan-binding protein levels in plasma and upper airways secretions and frequency of genotypes in children recurrence of otitis media. Clin Exp Immunol 1993; 94: 99-104.
2. Turner MW. Mannose-binding lectin: the pluripotent molecule of the innate immune system. Immunol Today 1996; 17: 532-540.
3. Alan R, Ezekowitz B. Genetic heterogeneity of mannose-binding proteins: the Jekyll and Hyde of innate immunity? Am J Hum Genet 1998; 62: 6-9.
4. Taylor ME, Brickell PM, Craig RK, Summerfield RA. Structure and evolutionary origin of the gene encoding a human serum mannose-binding protein. Biochem J 1989; 262: 763-771.
5. Sastry K, Herman GA, Day L, et al. The human mannose-binding protein gene: exon structure reveals its evolutionary relationship to a human pulmonary surfactant gene and localization to chromosome 10. J Exp Med 1989; 170: 1175-1189.
6. Lipscombe RJ, Sumiya M, Hill AV, et al. High frequencies in African and non-African populations of independent mutations in the mannose-binding protein gene. Hum Mol Genet 1992; 1: 709-715.
7. Madsen HO, Garred P, Kurtzhals JA, et al. A new frequent allele is the missing link in the structural polymorphism of the human mannose-binding protein. Immunogenetics 1994; 40: 37-44.
8. Sumiya M, Super M, Tabona P, et al. Molecular basis of opsonic defect in immunodeficient children. Lancet 1991; 337: 1569-1570.
9. Madsen HO, Garred P, Thiel S, et al. Interplay between promoter and structural gene variants contro basal serum level of mannan-binding protein. Mannan-binding protein. J Immunol 1995; 155: 3013-3020.
10. Crosdale DJ, Ollier WE, Thomson W, et al. Mannose binding lectin (MBL) genotype distributions with relation to serum levels in UK Caucasoids. Eur J Imunogenet 2000; 27: 111-117.
11. Garred P, Madsen HO, Kurtzhals JA, et al. Diallelic polymorphism may explain variations of the blood concentration of mannan-binding protein in Eskimos, but not in black Africans. Eur J Immunogenet 1992; 19: 403-412.
12. Foster CB, Lehrnbecher T, Mol F, et al. Host defense molecule polymorphisms influence the risk for immune-mediated complications in chronic granulomatous disease. J Clin Invest 1998; 102: 2146-2155.
13. Ip WK, Chan SY, Lau CS, Lau YL. Association of systemic lupus erythematosus with promoter polymorphisms of the mannose-binding lectin gene. Arthritis Rheum 1998; 41: 1663-1668.
14. Kilpatrick DC, James VS, Blackwell CC, Weir DM, Hallam NF, Busuttil A. Mannan binding lectin and sudden infant death syndrome. Forensic Sci Int 1998; 97: 135-138.
15. Summerfield JA, Sumiya M, Levin M, Turner MW. Association of mutations in mannose binding protein gene with childhood infection in consecutive hospital series. Br Med J 1997; 314: 1229-1232.
16. Wang Z-Y, Morinobu A, Kanagawa S, Kumagai S. Polymorphisms of the mannose binding lectin gene in patients with Sjögren's syndrome. Ann Rheum Dis 2001; 60: 483-486.
17. Garred P, Richter C, Andersen AB, et al. Mannan-binding lectin in the sub-Saharan HIV and tuberculosis epidemics. Scand J Immunol 1997; 46: 204-208.
18. Garred P, Pressler T, Madsen HO, et al. Association of mannose-binding lectin gene heterogeneity with severity of lung disease and survival in cystic fibrosis. J Clin Invest 1999; 104: 431-437.
19. Hoal-Van Helden EG, Epstein J, Victor TC, et al. Mannose-binding protein B allele confers protection against tuberculous meningitis. Pediatr Res 1999; 45: 459-464.
20. Miller SA, Dykes DD, Polesky HF. A simple salting-out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1998; 16: 1215.