NusA modulates intragenic termination by different pathways

Gene

Volumn 308, Issue 1-2, 2003, Pages 115-128

  Carlomagno, M Stella ^a   Nappo, Annagiulia ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

boxA; his operon; Polarity; Rho dependent termination; rut sites

Indexed keywords

MESSENGER RNA; PROTEIN; PROTEIN NUSA; PROTEIN NUSB; PROTEIN NUSE; RHO FACTOR; RNA POLYMERASE; UNCLASSIFIED DRUG;

ARTICLE; CISTRON; GENE CONTROL; GENETIC ANALYSIS; GENETIC PROCEDURES; GENETIC TRANSCRIPTION; IN VITRO STUDY; IN VIVO STUDY; INTRAGENIC TERMINATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REGULATOR GENE; RIBOSOME; RNA TRANSLATION; TRANSCRIPTION REGULATION;

EID: 0038581264     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(03)00472-4     Document Type: Article

References (34)

1. Alifano P., Ciampi M.S., Nappo A.G., Bruni C.B., Carlomagno M.S. In vivo analysis of the mechanisms responsible for strong transcriptional polarity in a sense mutant within an intercistronic region. Cell. 55:1988;351-360.
2. Alifano P., Rivellini F., Limauro D., Bruni C.B., Carlomagno M.S. A consensus motif common to all Rho-dependent prokaryotic transcription terminators. Cell. 64:1991;553-563.
3. Alifano P., Piscitelli C., Blasi V., Rivellini F., Nappo A.G., Bruni C.B., Carlomagno M.S. Processing of a polycistronic mRNA requires a 5′ cis element and active translation. Mol. Microbiol. 6:1992;787-798.
4. Alifano P., Rivellini F., Piscitelli C., Arraiano C.M., Bruni C.B., Carlomagno M.S. Ribonuclease E provides substrates for ribonuclease P-dependent processing of a polycistronic mRNA. Genes Dev. 8:1994;3021-3031.
5. Alifano P., Rivellini F., Nappo A.G., Bruni C.B., Carlomagno M.S. Alternative patterns of his operon transcription and mRNA processing generated by methabolic perturbation. Gene. 146:1994;15-21.
6. Burns C.M., Richardson L., Richardson J.P. Combinatorial effects of NusA and NusG on transcription elongation and rho-dependent termination in Escherichia coli. J. Mol. Biol. 275:1998;307-316.
7. Carlomagno M.S., Nappo A. The antiterminator NusB enhances termination at a sub-optimal Rho site. J. Mol. Biol. 309:2001;19-28.
8. Carlomagno M.S., Riccio A., Bruni C.B. Convergently functional. Rho-independent terminator in Salmonella typhimurium. J. Bacteriol. 163:1985;362-368.
9. Carlomagno M.S., Chiariotti L., Alifano P., Nappo A.G., Bruni C.B. Structure and function of the Salmonella typhimurium and Escherichia coli K-12 histidine operons. J. Mol. Biol. 203:1988;585-606.
10. Chan C.L., Landick R. The Salmonella typhimurium his operon leader region contains an RNA hairpin-dependent transcription pause site. Mechanistic implications of the effect on pausing of altered RNA hairpins. J. Biol. Chem. 264:1989;20796-20804.
11. Ciampi M.S., Alifano P., Nappo A.G., Bruni C.B., Carlomagno M.S. Features of the Rho-dependent transcription termination polar element within the hisG cistron of Salmonella typhimurium. J. Bacteriol. 171:1989;4472-4478.
12. Craven M.G., Friedman D.I. Analysis of the Escherichia coli nusA10(Cs) allele: relating nucleotide changes to phenotypes. J Bacteriol. 173:1991;1485-1491.
13. Friedman D.I., Court D.L. Transcription antitermination: the λ paradigm updated. Mol. Microbiol. 18:1995;191-200.
14. Friedman D.I., Schauer A.T., Baumann M.R., Baron L.S., Adhya S.L. Evidence that ribosomal protein S10 participates in control of transcription termination. Proc. Natl. Acad. Sci. USA. 78:1981;1115-1118.
15. Jin D.J., Burgess R.R., Richardson J.P., Gross C.A. Termination efficiency at rho-dependent terminators depends on kinetic coupling between RNA polymerase and Rho. Proc. Natl. Acad. Sci. USA. 89:1992;1453-1457.
16. Kainz M., Gourse R.L. The C-terminal domain of the alpha subunit of Escherichia coli RNA polymerase is required for efficient Rho-dependent transcription termination. J. Mol. Biol. 284:1998;1379-1390.
17. Lau L.F., Roberts J.W., Wu R. RNA polymerase pausing and transcript release at the λ tR1 terminator in vitro. J. Biol. Chem. 258:1983;9391-9397.
18. Mogridge J., Greenblatt J. Specific binding of Escherichia coli ribosomal protein S1 to boxA transcriptional antiterminator RNA. J. Bacteriol. 180:1998;2248-2252.
19. Nodwell J.R., Greenblatt J. Recognition of boxA antiterminator RNA by the E. coli antitermination factors NusB and ribosomal protein S10. Cell. 72:1993;261-268.
20. Rivellini F., Alifano P., Piscitelli C., Blasi V., Bruni C.B., Carlomagno M.S. A cytosine over guanosine-rich sequence in RNA activates Rho-dependent transcription termination. Mol. Microbiol. 5:1991;3049-3054.
21. Roberts J.W. Transcription termination and its regulation. Lin E.C.C., Linch A.S. Regulation of Gene Expression in Escherichia coli. 1996;27-45 Chapman Hall, New York, NY.
22. Ruteshouser E.C., Richardson J.P. Identification and characterization of transcription termination sites in the Escherichia coli lacZ gene. J. Mol. Biol. 208:1989;23-43.
23. Schauer A.T., Carver D.L., Bigelow B., Baron L.S., Friedman D.I. λ N antitermination system: functional analysis of phage interactions with the host NusA protein. J. Mol. Biol. 194:1987;679-690.
24. Sha Y., Lindahl L., Zengel J.M. Role of NusA in L4-mediated attenuation control of the S10 r-protein operon of Escherichia coli. J. Mol. Biol. 245:1995;474-485.
25. Sigmund C.D., Morgan E.A. Nus A protein affects transcriptional pausing and termination in vitro by binding to different sites on the transcription complex. Biochemistry. 27:1988;5622-5627.
26. Torres M., Condon C., Balada J.M., Squires C., Squires C.L. Ribosomal protein S4 is a transcription factor with properties remarkably similar to NusA, a protein involved in both non-ribosomal and ribosomal RNA antitermination. EMBO J. 20:2001;3811-3820.
27. Vogel U., Jensen K.F. NusA is required for ribosomal antitermination and for modulation of the transcription elongation rate of both antiterminated RNA and mRNA. J. Biol. Chem. 272:1997;12265-12271.
28. Ward D.F., Gottesman M.E. The nus mutations affect transcription termination in Escherichia coli. Nature. 292:1981;212-215.
29. Weisberg R.A., Gottesman M.E. Processive antitermination. J. Bacteriol. 181:1999;359-367.
30. Worbs M., Bourenkov G.P., Bartunik H.D., Huber R., Wahl M.C. An extended RNA binding surface through arrayed S1 and KH domains in transcription factor NusA. Mol. Cell. 7:2001;1177-1189.
31. Zellars M., Squires C.L. Antiterminator-dependent modulation of transcription elongation rates by NusB and NusG. Mol. Microbiol. 32:1999;1296-1304.
32. Zheng C., Friedman D.I. Reduced Rho-dependent transcription termination permits NusA-independent growth of Escherichia coli. Proc. Natl. Acad. USA. 91:1994;7543-7547.
33. Zhou Y., Mah T.F., Yu Y.T., Mogridge J., Olson E.R., Greenblatt J., Friedman D.I. Interactions of an Arg-rich region of transcription elongation protein NusA with NUT RNA: implications for the order of assembly of the λ N antitermination complex in vivo. J. Mol. Biol. 310:2001;33-49.
34. Zuker M. On finding all suboptimal foldings of an RNA molecule. Science. 244:1989;48-52.