Animal models for asthma: Controversial aspects and unsolved problems

Pathobiology

Volumn 70, Issue 5, 2002, Pages 252-254

  Pabst, R ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Asthma; Immune reactions; Models; Mouse

Indexed keywords

ALLERGEN; CELL ADHESION MOLECULE; CHEMOKINE; CYTOKINE;

ALLERGIC ASTHMA; ANIMAL MODEL; ANTIGEN PRESENTING CELL; BRONCHIAL ARTERY; CELL FUNCTION; CELL INTERACTION; CELL STRUCTURE; CELL TYPE; CONFERENCE PAPER; CYTOKINE PRODUCTION; CYTOPATHOLOGY; DENDRITIC CELL; DOG; EOSINOPHIL; EPITHELIUM CELL; HUMAN; IMMUNITY; IMMUNOCOMPETENT CELL; INCIDENCE; LAMINA PROPRIA; LUNG BLOOD VESSEL; LYMPHOCYTE SUBPOPULATION; MAST CELL; NONHUMAN; PATHOPHYSIOLOGY; PNEUMONIA; PRIORITY JOURNAL; RAT STRAIN; RESPIRATORY SYNCYTIAL PNEUMOVIRUS;

ANIMALS; ASTHMA; DISEASE MODELS, ANIMAL; HUMANS; MICE; RATS;

ANIMALIA; RODENTIA;

EID: 0038580375     PISSN: 10152008     EISSN: None     Source Type: Journal    
DOI: 10.1159/000070737     Document Type: Conference Paper

References (18)

1. Umetsu DT, McIntire JJ, Akbari O, Macaubas C, DeKruyff RH: Asthma: An epidemic of dys-regulated immunity. Nat Immunol 2002;3:715-720.
2. Lloyd CM, Gonzalo JA, Coyle AJ, Gutierrez-Ramos JC: Mouse models of allergic airway disease. Adv Immunol 2001;77:263-295.
3. Kumar RK, Foster PS: Modeling allergic asthma in mice: Pitfalls and opportunities. Am J Respir Cell Mol Biol 2002;27:267-272.
4. Zuercher AW, Cebra JJ: Structural and functional differences between putative mucosal inductive sites of the rat. Eur J Immunol 2002;32:3191-3196.
5. Hylkema MN, Hoekstra MO, Luinge M, Timens W: The strength of the OVA-induced airway inflammation in rats is strain dependent. Clin Exp Immunol 2002;129:390-396.
6. Schuster M, Tschernig T, Krug N, Pabst R: Lymphocytes migrate from the blood into the bronchoalveolar lavage and lung parenchyma in the asthma model of the Brown Norway rat. Am J Respir Crit Care Med 2000;161:558-566.
7. Ewaldsson B, Fogelmark B, Feinstein R, Ewaldsson L, Rylander R: Microbial cell wall product contamination of bedding may induce pulmonary inflammation in rats. Lab Anim 2002;36:282-290.
8. Gajewska BU, Swirski FK, Alvarez D, Ritz SA, Goncharova S, Cundall M, Snider DP, Coyle AJ, Gutierrez-Ramos JC, Stämpfli MR, Jordana M: Temporal-spatial analysis of the immune response in a murine model of ovalbumin-induced airways inflammation. Am J Respir Cell Mol Biol 2001;25:326-334.
9. Pabst R, Tschernig T: Perivascular capillaries in the lung: An important but neglected vascular bed in immune reactions? J Allergy Clin Immunol 2002;110:209-214.
10. Oldham MJ, Phalen RF: Dosimetry implications of upper tracheobronchial airway anatomy in two mouse varieties. Anat Rec 2002;268:59-65.
11. Redman TK, Rudolph K, Barr EB, Bowen LE, Muggenburg A, Bice DE: Pulmonary immunity to ragweed in a Beagle dog model of allergic asthma. Exp Lung Res 2001;27:433-451.
12. Pawankar R: Gamma delta T cells in allergic airway diseases. Clin Exp Allergy 2000;30:318-323.
13. Russo M, Nahori MA, Lefort J, Gomes E, de Castro Keller A, Rodriguez D, Ribeiro OG, Adriouch S, Gallois V, de Faria AMC, Vargaftig BB: Suppression of asthma-like responses in different mouse strains by oral tolerance. Am J Respir Cell Mol Biol 2001;24:518-526.
14. Lambrecht BN, Hoogsteden HC, Pauwels RA: Dendritic cells as regulators of the immune response to inhaled allergen: Recent findings in animal models of asthma. Int Arch Allergy Immunol 2001;124:432-446.
15. Lambrecht BN, Hamad H: The other cells in asthma: Dendritic cells and epithelial cell crosstalk. Curr Opin Pulm Med 2003;9:34-41.
16. Holt PG, Sly PD: Interactions between RSV infection, asthma, and atopy: Unraveling the complexities. J Exp Med 2002;196:1271-1275.
17. Gelfand EW: Mice are a good model of human airway disease. Am J Respir Crit Care Med 2002;166:5-6.
18. Persson CGA: Mice are not a good model of human airway disease. Am J Respir Crit Care Med 2002;166:6-7.