Expression of Wnt and Notch pathway genes in a pluripotent human embryonal carcinoma cell line and embryonic stem cells

APMIS

Volumn 111, Issue 1, 2003, Pages 197-211

  Walsh, James ^a   Andrews, Peter W ^a   Oosterhuis, J Wolter ^b   Von Eyben, Finn Edler ^b  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b NONE

Author keywords

Embryonal carcinoma; Embryonic stem; Frizzled; Neurogenesis; Notch; Wnt

Indexed keywords

LIGAND; NOTCH RECEPTOR; RECEPTOR; RETINOIC ACID; WNT PROTEIN;

CANCER CELL CULTURE; CANCER GENETICS; CELL CULTURE; CELL DIFFERENTIATION; COMPARATIVE STUDY; CONFERENCE PAPER; DNA LIBRARY; EMBRYONAL CARCINOMA; FZD 1 GENE; FZD 3 GENE; FZD 4 GENE; FZD 5 GENE; FZD 6 GENE; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC CODE; GENETIC TRANSCRIPTION; HUMAN; MALIGNANT NEOPLASTIC DISEASE; MOLECULAR MECHANICS; MULTIGENE FAMILY; NERVOUS SYSTEM DEVELOPMENT; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN INTERACTION; REGULATORY MECHANISM; STEM CELL; TERATOCARCINOMA;

CARCINOMA, EMBRYONAL; CELL DIFFERENTIATION; CELL LINE; FOLLISTATIN-RELATED PROTEINS; FRIZZLED RECEPTORS; GENE EXPRESSION REGULATION; GLYCOPROTEINS; HUMANS; MEMBRANE PROTEINS; MORPHOGENESIS; PLURIPOTENT STEM CELLS; PROTO-ONCOGENE PROTEINS; RECEPTOR, NOTCH1; RECEPTOR, NOTCH2; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; STEM CELLS; TRANSCRIPTION FACTORS; TRETINOIN; TUMOR CELLS, CULTURED; WNT PROTEINS; ZEBRAFISH PROTEINS;

EID: 0038561134     PISSN: 09034641     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0463.2003.1110124.x     Document Type: Conference Paper

References (63)

1. Kleinsmith LJ, Pierce GB. Multipotentiality of single embryonal carcinoma cells. Cancer Res 1964;24:1544-51.
2. Stevens LC, Hummel KP. A description of spontaneous congenital testicular teratomas in strain 129 mice. J Nat Cancer Inst 18:719-47.
3. Martin GR. Teratocarcinomas and mammalian embryogenesis. Science 1980;209:768-75.
4. Solter D, Damjanov I. Teratocarcinomas and the expression of oncodevelopmental genes. Methods Cancer Res 1979;18:277-332.
5. Evans MJ, Kaufman MH. Establishment in culture of pluripotential cells from mouse embryos. Nature 1981;292:154-6.
6. Martin GR. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci USA 1981;78:7634-6.
7. Reubinoff BE, Pera ME Fong C-Y, Trounson A, Bongso A. Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro. Nat Biotech 2000;18:399-404.
8. Thomson JA, Itskovitz-Eldor J, Shapiro SS, Waknitz MA, Swiergiel JJ, Marshall VS, et al. Embryonic Stem Cell Lines Derived from Human Blastocysts. Science 1998;282:1145-7.
9. Andrews PW. Retinoic Acid Induces Neuronal Differentiation of a Cloned Human Embryonal Carcinoma Cell Line in Vitro. Dev Biol 1984;103:285-93.
10. McBurney MW, Jones-Villeneuve EM, Edwards MK, Anderson PJ. Control of muscle and neuronal differentiation in a cultured embryonal carcinoma cell line. Nature 1982;299:165-7.
11. Cadigan KM, Nusse R. Wnt signaling: a common theme in animal development. Genes Dev 1997;11:3286-305.
12. Weinmaster G. The Ins and Outs of Notch Signaling. Mol Cell Neurosci 1997;9:91-102.
13. Bhanot P, Brink M, Samos CH, Hsieh JC, Wang Y, Macke JP, et al. A new member of the frizzled family from Drosophila functions as a Wingless receptor. Nature 1996;382:225-30.
14. Wang Y, Macke JP, Abella BJ, Andreasson K, Worley P, Gilbert DJ, et al. A Large Family of Putative Transmembrane Receptors Homologous to the Product of the Drosophila Tissue Polarity Gene frizzled. J Biol Chem 1996;271:4468-76.
15. Rattner A, Hsieh JC, Smallwood PM, Gilbert D J, Copeland NG, Jenkins NA, et al. A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors. Proc Natl Acad Sci USA 1997;94:2859-63.
16. Piccolo S, Agius E, Leyns L, Bhattacharyya S, Grunz H, Bouwmeester T, De Robertis EM. The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals. Nature 1999;397:707-10.
17. Glinka A, Wu W, Delius H, Monaghan AP, Blumenstock C, Niehrs C. Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction. Nature 1998;391:357-62.
18. Hsieh JC, Kodjabachian L, Rebbert ML, Rattner A, Smallwood PM, Samos CH. A new secreted protein that binds to Wnt proteins and inhibits their activities. Nature 1999;398:431-6.
19. Ikeda S, Kishida S, Yamamoto H, Murai H, Koyama S, Kikuchi A. Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin. EMBO J 1998;17:1371-84.
20. Hart MJ, de los Santos R, Albert IN, Rubinfeld B, Polakis P. Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta. Curr Biol 1998;8:573-81.
21. Behrens J, von Kries JP, Kuhl M, Bruhn L, Wedlich D, Grosschedl R, et al. Functional interaction of beta-catenin with the transcription factor LEF-1. Nature 1996;382:638-42.
22. Molenaar M, van de Wetering M, Oosterwegel M, Peterson-Maduro J, Godsave S, Korinek V, et al. XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos. Cell 1996;86:391-9.
23. Hecht A, Vleminckx K, Stemmler MP, van Roy F, Kemler R. The p300/CBP acetyltransferases function as transcriptional coactivators of beta-catenin in vertebrates. EMBO J 2000;19:1839-50.
24. Waltzer L, Bienz M. Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling. Nature 1998;395:521-5.
25. Cavallo RA, Cox RT, Moline MM, Roose J, Polevoy GA, Clevers H, et al. Drosophila Tcf and Groucho interact to repress Wingless signalling activity. Nature 1998;395:604-8.
26. Roose J, Molenaar M, Peterson J, Hurenkamp J, Brantjes H, Moerer P, et al. The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors. Nature 1998;395:608-12.
27. Li L, Yuan H, Xie W, Mao J, Caruso AM, McMahon A, et al. Dishevelled proteins lead to two signaling pathways. Regulation of LEF-1 and c-Jun N-terminal kinase in mammalian cells. J Biol Chem 1999;274:129-34.
28. Slusarski DC, Corces VG, Moon RT. Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signalling. Nature 1997;390:410-3.
29. Fleming RJ, Scottgale TN, Diederich RJ, Artavanis-Tsakonas S. The gene Serrate encodes a putative EGF-like transmembrane protein essential for proper ectodermal development in Drosophila melanogaster. Genes Dev 1990;4:2188-201.
30. Gu Y, Hukriede NA, Fleming RJ. Serrate expression can functionally replace Delta activity during neuroblast segregation in the Drosophila embryo. Development 1995;121:855-65.
31. Rebay I, Fleming RJ, Fehon RG, Cherbas L, Cherbas P, Artavanis-Tsakonas S. Specific EGF repeats of Notch mediate interactions with Delta and Serrate: implications for Notch as a multi-functional receptor. Cell 1991;67:687-99.
32. Schroeter EH, Kisslinger JA, Kopan R. Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain. Nature 1998;393:382-6.
33. Hsieh JJ, Henkel T, Salmon P, Robey E, Peterson MG, Hayward SD. Truncated mammalian Notchl activates CBF1/RBPJk-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2. Mol Cell Biol 1996;16:952-9.
34. Lu FM, Lux SE. Constitutively active human Notch1 binds to the transcription factor CBF1 and stimulates transcription through a promotor containing a CBF 1-responsive element. Proc Natl Acad Sci USA 1996;93:5663-7.
35. Matsuno K, Go MJ, Sun X, Eastman DS, Artavanis-Tsakonas S. Suppressor of Hairless-independent events in Notch signaling imply novel pathway elements. Development 1997;124:4265-73.
36. Shawber C, Nofziger D, Hsieh JJ-D, Lindsell C, Bogler O, Hayward D, et al. Notch signaling inhibits muscle cell differentiation through a CBF1-independent pathway. Development 1996;122:3765-73.
37. Bailey AM, Posakony JW. Suppressor of hairless directly activates transcription of enhancer of split complex genes in response to Notch receptor activity. Genes Dev 1995;9:2609-22.
38. Beatus P, Lundkvist J, Oberg C, Lendahl U. The Notch 3 intracellular domain represses Notch 1-mediated activation through Hairy/Enhancer of split (HES) promotors. Development 1999;126:3925-35.
39. Heitzler P, Bourouis M, Ruel L, Carteret C, Simpson P Genes of the Enhancer of split and achaete-scute complexes are required for a regulatory loop between Notch and Delta during lateral signalling in Drosophila. Development 1996;122:161-71.
40. Couso JP, Bishop SA, Martinez-Arias A. The wingless signalling pathway and the patterning of the wing margin in Drosophila. Development 1994;120:621-36.
41. Phillips RG, Whittle JRS. Wingless expression mediates determination of peripheral nervous system elements in late stages of Drosophila wing disc development. Development 1993;118:427-38.
42. de Cells JF, Bray S. Feed-back mechanisms affecting Notch activation at the dorsoventral boundary in the Drosophila wing. Development 1997;124:3241-51.
43. Brennan K, Klein T, Wilder E, Martinez-Arias A. Wingless Modulates the Effects of Dominant Negative Notch Molecules in the Developing Wing of Drosophila. Dev Biol 1999;216:210-29.
44. Wesley CS. Notch and Wingless Regulate Expression of Cuticle Patterning Genes. Mol Cell Biol 1999;19:5743-58.
45. Wesley CS, Saez L. Notch responds differently to Delta and Wingless in cultured Drosophila cells. J Biol Chem 2000;275:9099-101.
46. Axelrod JD, Matsuno K, Artavanis-Tsakonas S, Perrimon N. Interaction between Wingless and Notch signalling pathways mediated by dishevelled. Science 1996;271:1826-32.
47. Lako M, Lindsay S, Lincoln J, Cairns PM, Armstrong L, Hole N. Characterisation of Wnt gene expression during the differentiation of murine embryonic stem cells in vitro: role of Wnt3 in enhancing haematopoietic differentiation. Mech Dev 2001;103:49-59.
48. Smolich BD, Papkoff J. Regulated Expression of Wnt Family Members during Neurectodermal Differentiation of P19 Embryonal Carcinoma Cells: Overexpression of Wnt-1 Perturbs Normal Differentiation-Specific Properties. Dev Biol 1994;166:300-10.
49. Katoh M. Regulation of WNT3 and WNT3A mRNAs in human cancer cell lines NT2, MCF-7, and MKN45. Int J Oncology 2002;20:373-7.
50. Saitoh T, Mine T, Katoh M. Expression and regulation of WNT8A and WNT8B mRNAs in human tumor cell lines: Up-regulation of WNT8B mRNA by beta-estradiol in MCF-7 cells, and down-regulation of WNT8A and WNT8B mRNAs by retinoic acid in NT2 cells. Int J Oncology 2002;20:999-1003.
51. Wakeman JA, Walsh J, Andrews PW. Human Wnt-13 is developmentally regulated during the differentiation of NTERA-2 pluripotent human embryonal carcinoma cells. Oncogene 1998;17:179-86.
52. Andrews PW, Damjanov I, Simon D, Banting G, Carlin C, Dracopoli NC, et al. Pluripotent embryonal carcinoma clones derived from the human teratocarcinoma cell line Tera-2: Differentiation in vivo and in vitro. Lab Invest 1984;50:147-62.
53. Kirikoshi H, Koike J, Sagara N, Saitoh T, Tokuhara M, Tanaka K, et al. Molecular Cloning and Genomic Structure of Human Frizzled-3 at chromosome 8p21. Biochem Biophys Res Commun 2000;271:8-14.
54. Ackerman SL, Knowles BB, Andrews PW. Gene regulation during neuronal and non-neuronal differentiation of NTERA2 human teratocarcinoma-derived stem cells. Brain Res Mol Brain Res 1994;25:157-62.
55. Yang-Snyder J, Miller JR, Brown JD, Lai CJ, Moon RT. A frizzled homolog functions in a vertebrate Wnt signaling pathway. Curr Biol 1996;6:1302-6.
56. Shimizu K, Chiba S, Kumanu K, Hosoya N, Takahashi T, Kanda Y, et al. Mouse Jagged 1 Physically Interacts with Notch2 and Other Notch Receptors. J Biol Chem 1999;274:32961-9.
57. de la Pompa JL, Wakeham A, Correia KM, Samper E, Brown S, Aguilera R J, et al. Conservation of the Notch signalling pathway in mammalian neurogenesis. Development 1997;124:1139-48.
58. Lindsell CE, Boulter J, diSibio G, Gossler A, Weinmaster G. Expression Patterns of Jagged, Deltal, Notchl, Notch2, and Notch3 Genes Identify Ligand-Receptor Pairs That May Function in Neural Development. Mol Cell Neurosci 1996;8:14-27.
59. Nye JS, Kopan R. Vertebrate ligands for Notch. Curr Biol 1995;5:966-9.
60. Lardelli M, Williams R, Mitsiadis T, Lendahl U. Expression of the Notch 3 intracellular domain in mouse central nervous system progenitor cells is lethal and leads to disturbed neural tube development. Mech Dev 1996;59: 177-90.
61. Liu Y, Dehni G, Purcell KJ, Sokolow J, Carcangiu M, Artavanis-Tsakonas S, et al. Epithelial Expression and Chromosomal Location of Human TLE Genes: Implications for Notch Signaling and Neoplasia. Genomics 1996;31:58-64.
62. Rulifson EJ, Blair SS. Notch regulates wingless expression and is not required for the reception of the paracrine wingless signal during wing margin neurogenesis in Drosophila. Development 1995;121:2813-24.
63. Couso JP, Martinez-Arias A. Notch is required for wingless signaling in the epidermis of Drosophila. Cell 1994;79:259-72.