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Volumn 74, Issue 1, 2003, Pages 73-80

Long-term instability of alkaloid production by stably transformed cell lines of Catharanthus roseus

Author keywords

Cell culture; Genetic engineering; Secondary metabolism; Strictosidine synthase; Terpenoid indole alkaloids; Transgene expression; Tryptophan decarboxylase

Indexed keywords

ANTIBIOTICS; COMPOSITION; ENZYMES; GENES; PLANT CELL CULTURE;

EID: 0038558546     PISSN: 01676857     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1023368309831     Document Type: Article
Times cited : (45)

References (27)
  • 1
    • 0007538567 scopus 로고    scopus 로고
    • From genes to phytochemicals: The genomics approach to the characterization and utilization of plant secondary metabolism
    • Canel C (1999) From genes to phytochemicals: the genomics approach to the characterization and utilization of plant secondary metabolism. Acta Hort. 500: 51-58
    • (1999) Acta Hort. , vol.500 , pp. 51-58
    • Canel, C.1
  • 2
    • 0032127941 scopus 로고    scopus 로고
    • Effects of over-expression of strictosidine synthase and tryptophan decarboxylase on alkaloid production by cell cultures of Catharanthus roseus
    • Canel C, Lopes Cardoso MI, Whitmer S, van der Fits L, Pasquali G, van der Heijden R, Hoge JHC & Verpoorte R (1998) Effects of over-expression of strictosidine synthase and tryptophan decarboxylase on alkaloid production by cell cultures of Catharanthus roseus. Planta 205: 414-419
    • (1998) Planta , vol.205 , pp. 414-419
    • Canel, C.1    Lopes Cardoso, M.I.2    Whitmer, S.3    Van Der Fits, L.4    Pasquali, G.5    Van Der Heijden, R.6    Hoge, J.H.C.7    Verpoorte, R.8
  • 3
    • 0000748967 scopus 로고
    • Instability of indole alkaloid production in Catharanthus roseus cell suspension cultures
    • Deus-Neumann B & Zenk MH (1984) Instability of indole alkaloid production in Catharanthus roseus cell suspension cultures. Planta Med. 50: 427-431
    • (1984) Planta Med. , vol.50 , pp. 427-431
    • Deus-Neumann, B.1    Zenk, M.H.2
  • 4
    • 0005765030 scopus 로고
    • Enzymology of alkaloid production in plant cell cultures
    • Nijkamp HJJ, van der Plas LHW & van Aartrijk J (eds). Kluwer Academic Publishers, Dordrecht, The Netherlands
    • Galneder E & Zenk MH (1990) Enzymology of alkaloid production in plant cell cultures. In: Nijkamp HJJ, van der Plas LHW & van Aartrijk J (eds) Progress in Plant Cellular and Molecular Biology (pp. 754-762). Kluwer Academic Publishers, Dordrecht, The Netherlands
    • (1990) Progress in Plant Cellular and Molecular Biology , pp. 754-762
    • Galneder, E.1    Zenk, M.H.2
  • 6
    • 0038579012 scopus 로고
    • Restoration of cardenolide synthesis in redifferentiated shoots from callus of Digitalis purpurea
    • Hirotani M & Furuya T (1977) Restoration of cardenolide synthesis in redifferentiated shoots from callus of Digitalis purpurea. Phytochemistry 16: 610-611
    • (1977) Phytochemistry , vol.16 , pp. 610-611
    • Hirotani, M.1    Furuya, T.2
  • 7
    • 0013447399 scopus 로고
    • Elicitation of secondary product formation in Capsicum frutescens cultures
    • Robins RJ & Rhodes MJC (eds). Cambridge University Press, Cambridge
    • Holden MA, Holden PR & Yeoman MM (1988) Elicitation of secondary product formation in Capsicum frutescens cultures. In: Robins RJ & Rhodes MJC (eds) Manipulating Secondary Metabolism in Culture (pp. 57-65). Cambridge University Press, Cambridge
    • (1988) Manipulating Secondary Metabolism in Culture , pp. 57-65
    • Holden, M.A.1    Holden, P.R.2    Yeoman, M.M.3
  • 8
    • 0028190942 scopus 로고
    • Relationship between cell morphology and indole alkaloid production in suspension cultures of Catharanthus roseus
    • Kim SW, Jung KH, Kwak SS & Liu JR (1994) Relationship between cell morphology and indole alkaloid production in suspension cultures of Catharanthus roseus. Plant Cell Rep. 14: 23-26
    • (1994) Plant Cell Rep. , vol.14 , pp. 23-26
    • Kim, S.W.1    Jung, K.H.2    Kwak, S.S.3    Liu, J.R.4
  • 9
    • 0008865422 scopus 로고
    • Long term stability of alkaloid production in cell suspension cultures of Catharanthus roseus
    • Morris P, Scragg AH, Stafford A & Fowler MW (eds). Cambridge University Press, Cambridge
    • Morris P (1986) Long term stability of alkaloid production in cell suspension cultures of Catharanthus roseus.. In: Morris P, Scragg AH, Stafford A & Fowler MW (eds) Secondary Metabolism in Plant Cell Cultures (pp. 257-262). Cambridge University Press, Cambridge
    • (1986) Secondary Metabolism in Plant Cell Cultures , pp. 257-262
    • Morris, P.1
  • 10
    • 0003090417 scopus 로고
    • Regulation of product synthesis in cell cultures of Catharanthus roseus. V. Long-term maintenance of cells on a production medium
    • Morris P, Rudge K, Cresswell R & Fowler MW (1989) Regulation of product synthesis in cell cultures of Catharanthus roseus. V. Long-term maintenance of cells on a production medium. Plant Cell Tiss. Org. Cult. 17: 79-90
    • (1989) Plant Cell Tiss. Org. Cult. , vol.17 , pp. 79-90
    • Morris, P.1    Rudge, K.2    Cresswell, R.3    Fowler, M.W.4
  • 11
    • 84982358134 scopus 로고
    • A revised medium for rapid growth and bioassays with tobacco tissue cultures
    • Murashige T & Skoog F (1962) A revised medium for rapid growth and bioassays with tobacco tissue cultures. Physiol. Plant 15: 473-497
    • (1962) Physiol. Plant , vol.15 , pp. 473-497
    • Murashige, T.1    Skoog, F.2
  • 12
    • 0001928017 scopus 로고
    • Some accounts of variation (heterogeneity and/or instability) in secondary metabolites production by plant cell cultures
    • Ohta S & Verpoorte R (1992) Some accounts of variation (heterogeneity and/or instability) in secondary metabolites production by plant cell cultures. Ann. Rep. Nat. Sci. Home. Econ. 32: 9-23
    • (1992) Ann. Rep. Nat. Sci. Home. Econ. , vol.32 , pp. 9-23
    • Ohta, S.1    Verpoorte, R.2
  • 13
    • 0023655715 scopus 로고
    • Assay of tryptophan decarboxylase from Catharanthus roseus cell cultures by high-performance liquid chromatography
    • Pennings EJM, Hegger I, van der Heijden R, Duine JA & Verpoorte R (1987) Assay of tryptophan decarboxylase from Catharanthus roseus cell cultures by high-performance liquid chromatography. Anal. Biochem. 165: 33-136
    • (1987) Anal. Biochem. , vol.165 , pp. 33-136
    • Pennings, E.J.M.1    Hegger, I.2    Van Der Heijden, R.3    Duine, J.A.4    Verpoorte, R.5
  • 15
    • 0003147308 scopus 로고
    • High berberine producing cultures of Coptis japonica cells
    • Sato F & Yamada Y (1984) High berberine producing cultures of Coptis japonica cells. Phytochemistry 23: 281-285
    • (1984) Phytochemistry , vol.23 , pp. 281-285
    • Sato, F.1    Yamada, Y.2
  • 16
    • 0026755830 scopus 로고
    • Search for factors involved in indole alkaloid production in cell suspension cultures of Tabernaemontana divaricata
    • Schripsema J & Verpoorte R (1992) Search for factors involved in indole alkaloid production in cell suspension cultures of Tabernaemontana divaricata. Planta Med. 58: 245-249
    • (1992) Planta Med. , vol.58 , pp. 245-249
    • Schripsema, J.1    Verpoorte, R.2
  • 17
    • 0002335781 scopus 로고
    • Stability of alkaloid production in cell suspension cultures of Tabernaemontana divaricata during long-term subculture
    • Sierra MI, van der Heijden R, van der Leer T & Verpoorte R (1992) Stability of alkaloid production in cell suspension cultures of Tabernaemontana divaricata during long-term subculture. Plant Cell Tiss. Org. Cult. 28: 59-68
    • (1992) Plant Cell Tiss. Org. Cult. , vol.28 , pp. 59-68
    • Sierra, M.I.1    Van Der Heijden, R.2    Van Der Leer, T.3    Verpoorte, R.4
  • 18
    • 0002791054 scopus 로고
    • Variation in alkaloid production in Nicotiana rustica callus cultures
    • Tabata M & Hiraoka N (1976) Variation in alkaloid production in Nicotiana rustica callus cultures. Physiol. Plant 38: 19-23
    • (1976) Physiol. Plant , vol.38 , pp. 19-23
    • Tabata, M.1    Hiraoka, N.2
  • 19
    • 0001355026 scopus 로고
    • Pigment formation in callus cultures of Lithospermum erythrorhizon
    • Tabata M, Mizukami H, Hiraoka N & Konoshima M (1974) Pigment formation in callus cultures of Lithospermum erythrorhizon. Phytochemistry 13: 927-937
    • (1974) Phytochemistry , vol.13 , pp. 927-937
    • Tabata, M.1    Mizukami, H.2    Hiraoka, N.3    Konoshima, M.4
  • 20
    • 45949124875 scopus 로고
    • High-performance liquid chromatographic determination of indole alkaloids in a suspension cell culture of Tabernaemontana divaricata
    • Van der Heijden R, Lamping PJ, Wijnsma R & Verpoorte R (1987) High-performance liquid chromatographic determination of indole alkaloids in a suspension cell culture of Tabernaemontana divaricata. J. Chromatogr. 396: 287-295
    • (1987) J. Chromatogr. , vol.396 , pp. 287-295
    • Van Der Heijden, R.1    Lamping, P.J.2    Wijnsma, R.3    Verpoorte, R.4
  • 21
    • 77956657123 scopus 로고    scopus 로고
    • Plant biotechnology and the production of alkaloids: Prospects of metabolic engineering
    • Cordell GA (ed). Academic Press, San Diego
    • Verpoorte R, van der Heijden R & Memelink J (1998) Plant biotechnology and the production of alkaloids: prospects of metabolic engineering. In: Cordell GA (ed) The Alkaloids Vol. 50 (pp. 453-508). Academic Press, San Diego
    • (1998) The Alkaloids , vol.50 , pp. 453-508
    • Verpoorte, R.1    Van Der Heijden, R.2    Memelink, J.3
  • 22
    • 10844277123 scopus 로고    scopus 로고
    • Biosynthesis of terpenoid indole alkaloids in Catharanthus roseus cells
    • Cordell GA (ed). Academic Press, San Diego
    • Verpoorte R, van der Heijden R & Moreno PRH (1997) Biosynthesis of terpenoid indole alkaloids in Catharanthus roseus cells. In: Cordell GA (ed) The Alkaloids Vol. 49 (pp. 221-299). Academic Press, San Diego
    • (1997) The Alkaloids , vol.49 , pp. 221-299
    • Verpoorte, R.1    Van Der Heijden, R.2    Moreno, P.R.H.3
  • 23
    • 0029007274 scopus 로고
    • Expression of multiple eukaryotic genes from a single promoter in Nicotiana
    • Von Bodman SB, Domier LL & Farrand SK (1995) Expression of multiple eukaryotic genes from a single promoter in Nicotiana. Biotechnology 13: 587-591
    • (1995) Biotechnology , vol.13 , pp. 587-591
    • Von Bodman, S.B.1    Domier, L.L.2    Farrand, S.K.3
  • 24
    • 0036232568 scopus 로고    scopus 로고
    • Effect of precursor feeding on alkaloid accumulation by strictosidine synthase over-expressing transgenic cell line S1 of Catharanthus roseus
    • Whitmer S, van der Heijden R & Verpoorte R (2002a) Effect of precursor feeding on alkaloid accumulation by strictosidine synthase over-expressing transgenic cell line S1 of Catharanthus roseus. Plant Cell Tiss. Org. Cult. 69: 85-93
    • (2002) Plant Cell Tiss. Org. Cult. , vol.69 , pp. 85-93
    • Whitmer, S.1    Van Der Heijden, R.2    Verpoorte, R.3
  • 25
    • 0037178212 scopus 로고    scopus 로고
    • Effect of precursor feeding on alkaloid accumulation by a tryptophan decarboxylase overexpressing transgenic cell line T22 of Catharanthus roseus
    • Whitmer S, van der Heijden R & Verpoorte R (2002b) Effect of precursor feeding on alkaloid accumulation by a tryptophan decarboxylase overexpressing transgenic cell line T22 of Catharanthus roseus J. Biotechnol. 96: 193-203
    • (2002) J. Biotechnol. , vol.96 , pp. 193-203
    • Whitmer, S.1    Van Der Heijden, R.2    Verpoorte, R.3
  • 26
    • 0031720190 scopus 로고    scopus 로고
    • Influence of auxins on alkaloid accumulation by a transgenic cell line of Catharanthus roseus
    • Whitmer S, Verpoorte R & Canel C (1998) Influence of auxins on alkaloid accumulation by a transgenic cell line of Catharanthus roseus. Plant Cell Tiss. Org. Cult. 53: 135-141
    • (1998) Plant Cell Tiss. Org. Cult. , vol.53 , pp. 135-141
    • Whitmer, S.1    Verpoorte, R.2    Canel, C.3
  • 27
    • 0000984266 scopus 로고    scopus 로고
    • Tansley Review No 90 Manipulating secondary metabolism in cultured plant cells
    • Yeoman MM & Yeoman CL (1996) Tansley Review No 90 Manipulating secondary metabolism in cultured plant cells. New Phytol. 134: 553-569
    • (1996) New Phytol. , vol.134 , pp. 553-569
    • Yeoman, M.M.1    Yeoman, C.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.