Effect of in vivo administered hexachlorobenzene on epidermal growth factor receptor levels, protein tyrosine kinase activity, and phosphotyrosine content in rat liver

Biochemical Pharmacology

Volumn 65, Issue 9, 2003, Pages 1495-1506

  Randi, Andrea S ^a   Sancovich, Horacio A ^a   Ferramola De Sancovich, Ana M ^a   Loaiza, Andrea ^a   Kölliker Frers, Rodolfo A ^a   Spinelli, Fernanda ^a   Kleiman De Pisarev, Diana L ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

EGFR kinase activity; EGFR levels; Hexachlorobenzene; Phosphotyrosine content; Protein tyrosine kinase; Rat liver

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; HEXACHLOROBENZENE; PHOSPHOTYROSINE; PROTEIN TYROSINE KINASE;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; LIVER; LIVER CELL; LIVER MICROSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; REDUCTION; SIGNAL TRANSDUCTION; TOXICITY;

EID: 0038555827     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(03)00107-2     Document Type: Article

References (42)

1. Courtney K.D. Hexachlorobenzene: a review. Environ. Res. 20:1979;225-266.
2. Koss G., Koransky W., Steinbach K. Studies on the toxicology of hexachlorobenzene. II. Identification and determination of metabolites. Arch. Toxicol. 35:1976;107-114.
3. Brady M.N., Siyali D.S. Hexachlorobenzene in human body fat. Med. J. Aust. 1:1972;158-161.
4. van Raaij J.A.G.M., Kaptein E., Visser T.J., van den Berg K.J. Increased glucuronidation of thyroid hormone in hexachlorobenzene-treated rats. Biochem. Pharmacol. 45:1993;627-631.
5. Kleiman de Pisarev D.L., Ríos de Molina del C., San Martín de Viale L.C. Thyroid function and thyroxine metabolism in hexachlorobenzene-induced porphyria. Biochem. Pharmacol. 39:1990;817-825.
6. Sopena de Kracoff Y.E., Ferramola de Sancovich A.M., Sancovich H.A., Kleiman de Pisarev D.L. Effect of thyroidectomy and thyroxine on hexachlorobenzene induced porphyria. J. Endocrinol. Invest. 17:1994;301-305.
7. Billi de Catabbi S., Sterin-Speziale N., Fernandez M.C., Minutolo C., San Martín de Viale L.C. Time course of hexachlorobenzene-induced alteration of lipid metabolism and their relation to porphyria. Int. J. Biochem. Cell Biol. 29:1997;335-344.
8. Rozman K., Gorski J.R., Rozman P., Parkinson A. Reduced serum thyroid hormone levels in hexachlorobenzene induced porphyria. Toxicol. Lett. 30:1986;71-78.
9. Kleiman de Pisarev D.L., Sancovich H.A., Ferramola de Sancovich A.M. Enhanced thyroxine metabolism in hexachlorobenzene-intoxicated rats. J. Endocrinol. Invest. 12:1989;767-772.
10. Cabral J.R.P., Shubik P., Mollner T., Raitano F. Carcinogenic activity of hexachlorobenzene in hamsters. Nature. 269:1977;510-511.
11. Erturk E., Lambrecht R.W., Peters H.A., Cripps D.J., Gocmen A., Morris C.R., Bryan G.T. Oncogenicity of hexachlorobenzene. IARC Sci. Publ. 77:1986;417-423.
12. Stewart F.P., Manson M.M., Cabral J.R.P., Smith A.G. Hexachlorobenzene as a promoter of diethylnitrosamine-initiated hepatocarcinogenesis in rats and comparison with induction of porphyria. Carcinogenesis. 10:1989;1225-1230.
13. Mylchreest E., Charbonneau M. Studies on the mechanism of uroporphyrinogen decarboxylase inhibition in hexachlorobenzene-induced porphyria in the female rat. Toxicol. Appl. Pharmacol. 145:1997;23-33.
14. Hahn M.E., Goldstein J.A., Linko P., Gasiewicz T.A. Interaction of hexachlorobenzene with the receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in vitro and in vivo. Arch. Biochem. Biophys. 270:1989;344-355.
15. Matsumura F. How important is the protein phosphorylation pathway in the toxic expression of dioxin-type chemicals. Biochem. Pharmacol. 48:1994;215-224.
16. Kafafi S.A., Afeffy H.Y., Ali A.H., Said H.K., Kafafi A.G. Binding of polychlorinated biphenyls to the aryl hydrocarbon receptor. Environ. Health Perspect. 101:1993;422-428.
17. Fisher L.J., Seagal R.F., Ganey P.E., Pessah I.N., Kodavanti P.R.S. Symposium overview: toxicity of non-coplanar PCBs. Toxicol. Sci. 41:1998;49-61.
18. Randi A.S., Sancovich H.A., Ferramola de Sancovich A.M., Loaiza A.I., Krawiec L., Kleiman de Pisarev D.L. Hexachlorobenzene-induced alterations of rat hepatic microsomal membrane function. Toxicology. 125:1998;83-94.
19. Hunter T., Cooper J.A. Protein-tyrosine kinases. Review. Annu. Rev. Biochem. 54:1985;897-930.
20. Lai W.H., Cameron P.H., Wada I., Doherty J.J. II, Kay D.G., Posner B.I., Bergeron J.J.M. Ligand-mediated internalization, recycling, and downregulation of the epidermal growth factor receptor in vivo. J. Cell Biol. 109:1989;2741-2749.
21. Carpenter G, Wahl MI. The epidermal growth factor family. In: Sporn MB, Roberts AB, editors. Peptide growth factors and their receptors. New York: Springer; 1991. p. 69-133.
22. McCune B.K., Earp H.S. The epidermal growth factor receptor tyrosine kinase in liver epithelial cells. J. Biol. Chem. 264:1989;15501-15507.
23. Madhukar B.V., Brewster D.W., Matsumura F. Effects of in vivo administered 2,3,7,8-tetrachlorodibenzo-p-dioxin on receptor binding of epidermal growth factor in the hepatic plasma membrane of rat, guinea pig, mouse and hamster. Proc. Natl. Acad. Sci. U.S.A. 81:1984;7407-7411.
24. Madhukar B.V., Ebner K., Matsumura F., Bombick D.W., Brewster D.W., Kawamoto T. 2,3,7,8-Tetrachlorodibenzo-p-dioxin causes an increase in protein kinases associated with epidermal growth factor receptor in the hepatic plasma membrane. J. Biochem. Toxicol. 3:1988;261-277.
25. Hudson L.G., Toscano W.A. Jr., Greenlee W.F. Regulation of epidermal growth factor binding in a human keratinocyte cell line by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol. Appl. Pharmacol. 77:1985;251-259.
26. Hubbard A.L., Wall D.A., Ma A. Isolation of rat hepatocyte plasma membranes. I. Presence of the three major domains. J. Cell Biol. 96:1983;217-229.
27. Widnell C.C., Unkeless J.C. Partial purification of a lipoprotein with 5′-nucleotidase activity from membranes of rat liver cells. Proc. Natl. Acad. Sci. U.S.A. 61:1968;1050-1057.
28. Rubin R.A., O'Keefe E.J., Earp H.S. Alteration of epidermal growth factor-dependent phosphorylation during rat liver regeneration. Proc. Natl. Acad. Sci. U.S.A. 79:1982;776-780.
29. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248-254.
30. 4. Nature. 227:1970;680-685.
31. Countaway J.L., Nairn A.C., Davis R.J. Mechanism of desensitization of the epidermal growth factor receptor protein-tyrosine kinase. J. Biol. Chem. 267:1992;1129-1140.
32. Fresno Vara J.Á., Carretero M.V., Gerónimo H., Ballmer-Hofer K., Martín-Pérez J. Stimulation of c-Src by prolactin is independent of Jak2a. Biochem. J. 345:2000;17-24.
33. Tremblay L., Beliveau R. Protein tyrosine phosphorylation in normal rat tissues. Int. J. Biochem. 26:1994;29-34.
34. Lim C.K., Li F.M., Peters T.J. High-performance liquid chromatography of porphyrins. J. Chromatogr. 429:1988;123-153.
35. Wainstock de Calmanovici R., Billi S., Aldonatti C., San Martín de Viale L.C. Effect of desferrioxamine on the development of hexachlorobenzene-induced porphyria. Biochem. Pharmacol. 35:1986;2399-2405.
36. src, in murine hepatic cytosol using a cell-free system. Mol. Pharmacol. 52:1997;667-675.
37. Enan E., Matsumura F. Evidence for a second pathway in the action mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Significance of Ah-receptor mediated activation of protein kinase under cell-free conditions. Biochem. Pharmacol. 49:1995;249-261.
38. Wright J.D., Reuter C.W.M., Weber M.J. An incomplete program of cellular tyrosine phosphorylations induced by kinase-defective epidermal growth factor receptors. J. Biol. Chem. 270:1995;12085-12093.
39. Sewall C.H., Clark G.C., Lucier G.W. TCDD reduces rat hepatic epidermal growth factor receptor: comparison of binding, immunodetection, and autophosphorylation. Toxicol. Appl. Pharmacol. 132:1995;263-272.
40. Gustafson D.L., Long M.E., Thomas R.S., Benjamin S.A., Yang R.S.H. Comparative hepatocarcinogenicity of hexachlorobenzene, pentachlorobenzene, 1,2,4,5-tetrachlorobenzene, and 1,4-dichlorobenzene: application of a medium-term liver focus bioassay and molecular and cellular indices. Toxicol. Sci. 53:2000;245-252.
41. Quilley C.P., Rifkind A.B. Prostaglandin release by the chick embryo heart is increased by 2,3,7,8-tetrachlorodibenzo-p-dioxin and by other cytochrome P-448 inducers. Biochem. Biophys. Res. Commun. 136:1986;582-589.
42. Schrenk D., Karger A., Lipp H.P., Bock K.W. 2,3,7,8-Tetrachlorodibenzo-p-dioxin and ethinylestradiol as co-mitogens in cultured rat hepatocytes. Carcinogenesis. 13:1992;453-456.