NRAMP1 polymorphisms, susceptibility and clinical features of tuberculosis

Journal of Infection

Volumn 46, Issue 4, 2003, Pages 215-220

  Abe, T ^a   Iinuma, Y ^b   Ando, M ^c   Yokoyama, T ^a   Yamamoto, T ^a   Nakashima, K ^a   Takagi, N ^a   Baba, H ^c   Hasegawa, Y ^c   Shimokata, K ^c  

^a CHUBU NATIONAL HOSPITAL   (Japan)

^b NAGOYA UNIVERSITY HOSPITAL   (Japan)

^c NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE; ASPARTIC ACID; ETHAMBUTOL; ISONIAZID; NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN 1; PYRAZINAMIDE; RIFAMPICIN; STREPTOMYCIN;

ADULT; AGE; AGED; ALLELE; ARTICLE; CLINICAL FEATURE; CONFIDENCE INTERVAL; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE ASSOCIATION; DNA POLYMORPHISM; FEMALE; GENDER; GENETIC VARIABILITY; HUMAN; INFECTION SENSITIVITY; JAPAN; LOGISTIC REGRESSION ANALYSIS; LUNG TUBERCULOSIS; MAJOR CLINICAL STUDY; MALE; NONHUMAN; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

EID: 0038546537     PISSN: 01634453     EISSN: None     Source Type: Journal    
DOI: 10.1053/jinf.2002.1064     Document Type: Article

References (17)

1. Murray C, Styblo K, Rouillon A. Tuberculosis in developing countries: burden, intervention and cost. Bull Int Union Tuberc Lung Dis 1990; 65: 6-24.
2. Comstock GW. Tuberculosis in twins: a re-analysis of the Prophit survey. Am Rev Respir Dis 1978; 117: 621-624.
3. Gros P, Skamene E, Forget A. Genetic control of natural resistance to Mycobacterium bovis (BCG) in mice. J Immunol 1981; 127: 2417-2421.
4. Plant J, Glynn A. Genetics of resistance to infection with Salmonella typhimurium in mice. J Infect Dis 1976; 133: 72-78.
5. Bradley DJ. Regulation of Leishmania populations within the host. II. genetic control of acute susceptibility of mice to Leishmania donovani infection. Clin Exp Immunol 1977; 30: 130-140.
6. Vidal SM, Malo D, Vogan K, Skamene E, Gros P. Natural resistance to infection with intracellular parasites: isolation of a candidate for Bcg. Cell 1993; 73: 469-485.
7. Cellier M, Govoni G, Vidal S et al. Human natural resistance-associated macrophage protein: cDNA cloning, chromosomal mapping, genomic organization, and tissue-specific expression. J Exp Med 1994; 180: 1741-1752.
8. Shaw MA, Collins A, Peacock CS et al. Evidence that genetic susceptibility to Mycobacterium tuberculosis in a Brazilian population is under oligogenic control: linkage study of the candidate genes NRAMP1 and TNFA. Tuber Lung Dis 1997; 78: 35-45.
9. Bellamy R, Ruwende C, Corrah T, McAdam KP, Whittle HC, Hill AV. Variations in the NRAMP1 gene and susceptibility to tuberculosis in West Africans. N Engl J Med 1998; 338: 640-644.
10. Ryu S, Park YK, Bai GH, Kim SJ, Park SN, Kang S, 3′UTR polymorphisms in the NRAMP1 gene are associated with susceptibility to tuberculosis in Koreans. Int J Tuberc Lung Dis 2000; 4: 577-580.
11. Greenwood CM, Fujiwara TM, Boothroyd LJ et al. Linkage of tuberculosis to chromosome 2q35 loci, including NRAMP1, in a large aboriginal Canadian family. Am J Hum Genet 2000; 67: 405-416.
12. Liu J, Fujiwara TM, Buu NT et al. Identification of polymorphisms and sequence variants in the human homologue of the mouse natural resistance-associated macrophage protein gene. Am J Hum Genet 1995; 56: 845-853.
13. Gao P, Fujishima S, Mao X et al. Genetic variants of NRAMP1 and active tuberculosis in Japanese populations. Clin Genet 2000; 58: 74-76.
14. Vidal S, Tremblay ML, Govoni G et al. The Ity/Lsh/Bcg locus: natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp1 gene. J Exp Med 1995; 182: 655-666.
15. Rieder HL, Cauthen GM, Comstock GW, Snider DR, Jr. Epidemiology of tuberculosis in the United States. Epidemiol Rev 1989; 11: 79-98.
16. Gruenheid S, Pinner E, Desjardins M, Gros P. Natural resistance to infection with intracellular pathogens: The Nramp1 protein is recruited to the membrane of the phagosome. J Exp Med 1997; 185: 717-730.
17. Atkinson PGP, Barton CH. Ectopic expression of Nramp1 in COS-1 cells modulates iron accumulation. FEBS Lett 1998; 425: 239-242.