Sequences of yne-ene cross metathesis and Diels-Alder cycloaddition reactions - Modular solid phase synthesis of substituted octahydrobenzazepinones

Synlett

Volumn , Issue 12, 1999, Pages 1879-1882

  Schürer, Stephan C ^a   Blechert, Siegfried ^a  

^a TECHNISCHE UNIVERSITÄT BERLIN   (Germany)

Author keywords

1,3 dienes; Combinatorial chemistry; Cyclization cleavage; Diels Alder reactions; Yne ene metathesis

Indexed keywords

BENZAZEPINE DERIVATIVE;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; CYCLIZATION; REACTION ANALYSIS; SYNTHESIS;

EID: 0038545118     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1999-2961     Document Type: Article

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27. 2 / MeOH) and concentrated to yield crude product 21 in high purity.
28. 33NO (m/z) 339,2562, measured 339.2563.
29. 2EtN, DMF) with 4-hydroxymethylbenzoic acid followed by hydrolysis of ester side products (0.2M NaOMe in 3/1 THF/ MeOH).