The histamine H2-receptor antagonist, cimetidine, inhibits the Articular oteopenia in rats with adjuvant-induced arthritis by suppressing the osteoclast differentiation induced by histamine

Journal Pharmacological Sciences

Volumn 92, Issue 1, 2003, Pages 43-49

  Yamaura, Katsunori ^a   Yonekawa, Taeko ^a   Nakamura, Tomonori ^a   Yano, Shingo ^a   Ueno, Koichi ^a  

^a CHIBA UNIVERSITY   (Japan)

Author keywords

Bone mineral density; Cimetidine; Histamine; Osteoclast; Rat adjuvant arthritis

Indexed keywords

CALCIPOTRIOL; CIMETIDINE; DIMAPRIT; HISTAMINE; HISTAMINE H1 RECEPTOR ANTAGONIST; HISTAMINE H2 RECEPTOR AGONIST; HISTAMINE H2 RECEPTOR ANTAGONIST; MEPYRAMINE; PHOSPHATASE; PREDNISOLONE; HISTAMINE AGONIST;

ADJUVANT ARTHRITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE DENSITY; BONE MARROW CELL; CELL DIFFERENTIATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG INHIBITION; FEMALE; FEMUR; IN VIVO STUDY; MULTINUCLEAR CELL; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; OSTEOPENIA; PAW EDEMA; RAT; STATISTICAL SIGNIFICANCE; ANIMAL; ARTHRITIS; ARTICULAR CARTILAGE; COMPARATIVE STUDY; LEWIS RAT; PATHOLOGY; PHYSIOLOGY;

ANIMALS; ARTHRITIS, EXPERIMENTAL; BONE DENSITY; BONE RESORPTION; CARTILAGE, ARTICULAR; CELL DIFFERENTIATION; CIMETIDINE; DIMAPRIT; FEMALE; HISTAMINE; HISTAMINE AGONISTS; HISTAMINE H1 ANTAGONISTS; HISTAMINE H2 ANTAGONISTS; OSTEOCLASTS; PYRILAMINE; RATS; RATS, INBRED LEW;

EID: 0038542992     PISSN: 13478613     EISSN: None     Source Type: Journal    
DOI: 10.1254/jphs.92.43     Document Type: Article

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