Activation of the renin-angiotensin system contributes to the peripheral vasoconstriction reflexly caused by stomach distension in anaesthetized pigs

Experimental Physiology

Volumn 88, Issue 3, 2003, Pages 359-367

  Molinari, C ^a   Battaglia, A ^a   Grossini, E ^a   Florio, S ^b   Mary, D A S G ^a   Vassanelli, C ^a   Vacca, G ^a  

^a UNIVERSITY OF EASTERN PIEDMONT   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE; ANGIOTENSIN; ANGIOTENSIN I; ANGIOTENSIN RECEPTOR; CHLORALOSE; LOSARTAN; PHENTOLAMINE; RENIN; RINGER SOLUTION;

ANESTHESIA INDUCTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA CONSTRICTION; ARTICLE; BLOOD FLOW; CAROTID SINUS DENERVATION; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; EFFERENT NERVE; ELECTROMAGNETIC FLOWMETER; HEART ATRIUM PACING; HEART RATE; ILIAC ARTERY; KIDNEY BLOOD FLOW; MESENTERY BLOOD FLOW; NONHUMAN; PERFUSION PRESSURE; PERIPHERAL VASCULAR SYSTEM; PRESSORECEPTOR; RADIOIMMUNOASSAY; RECEPTOR BLOCKING; REGIONAL PERFUSION; RENAL ARTERY; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SENSORY NERVE; STOMACH DISTENSION; SUPERIOR MESENTERIC ARTERY; SWINE; SYMPATHETIC NERVE; TIME; VAGUS NERVE; VASOCONSTRICTION;

EID: 0038527120     PISSN: 09580670     EISSN: None     Source Type: Journal    
DOI: 10.1113/eph8802560     Document Type: Article

References (29)

1. Cotterel DF & Iggo A (1984). Tension receptors with vagal afferent fibres in the proximal duodenum and pyloric sphincter of sheep. J Physiol 354, 457-475.
2. Cowley AJ, Fullwood LJ, Stainer K, Harrison E, Muller AF & Hampton JR (1991). Postprandial worsening of angina. All due to change in cardiac output? Br Heart J 66, 147-150.
3. Davis JO & Freeman RH (1976). Mechanisms regulating renin release. Physiol Rev 56, 1-56.
4. Falempin M, Mei N & Rousseau JP (1978). Vagal mechanoreceptors of the inferior thoracic oesophagus, the lower oesophageal sphincter and the stomach in sheep. Pflugers Arch 373, 25-30.
5. Goldstein RE, Redwood DR, Rosing DR, Beiser GD & Epstein SE (1971). Alterations in the circulatory response to exercise following a meal and their relationship to post-prandial angina pectoris. Circulation 44, 90-100.
6. Grollman A (1929). Physiological variations in the cardiac output in man. III. The effect of the ingestion of food on the cardiac output, pulse rate, blood pressure, and oxygen consumption of man. Am J Physiol 89, 366-370.
7. Grundy D & Scratcherd T (1989). Sensory afferents from the gastrointestinal tract. In Handbook of Physiology, section 6, The Gastrointestinal System, ed. Schultz SG, Wood JD & Bauner BB, pp. 593-620. American Physiological Society, Bethesda, MD, USA.
8. Heyndrickx GR, Boettcher DH & Vatner SF (1976). Effects of angiotensin, vasopressin, and methoxamine on cardiac function and blood flow distribution in conscious dogs. Am J Physiol 231, 1579-1587.
9. Iggo A (1957). Gastrointestinal tension receptors with unmyelinated afferent fibres in the vagus of the cat. Q J Exp Physiol 42, 130-143.
10. Janig W & Morrison JFB (1986). Functional properties of spinal visceral afferents supplying abdominal and pelvic organs, with special emphasis on visceral nociception. In Visceral Sensation, ed. Cervero F & Morrison JFB, Progress in Brain Research, vol. 67, pp. 87-114. Elsevier, Amsterdam.
11. Kelbaek H, Munck O, Christensen NJ & Godtfredsen J (1989). Central haemodynamic changes after a meal. Br Heart J 61, 506-509.
12. Li P, Rowshan K, Crisostomo M, Tjen-A-Looi SC & Longhurst JC (2002). Effect of electroacupuncture on pressor reflex during gastric distension. Am J Physiol Regul Integr Comp Physiol 283, R1335-1345.
13. Linden RJ & Mary DASG (1983). The preparation and maintenance of anaesthetized animals for the study of cardiovascular function. In Techniques in Cardiovascular Physiology, ed. Linden RJ, pp. 1-22. Techniques in Life Sciences Series. Elsevier, Shannon.
14. Longhurst JC & Ibarra J (1982). Sympathoadrenal mechanisms in hemodynamic responses to gastric distension in cats. Am J Physiol 243, H748-753.
15. Longhurst JC, Spilker HL & Ordway GA (1981). Cardiovascular reflexes elicited by passive gastric distension in anesthetized cats. Am J Physiol 240, H539-545.
16. Massart P, Hodeige DG, Van Mechelen H, Charlier AA, Ketelslegers J, Heyndrickx GR & Donckier JE (1998). Angiotensin II and endothelin-1 receptor antagonists have cumulative hypotensive effects in canine Page hypertension. J Hypertens 16, 835-841.
17. Molinari C, Battaglia A, Grossini E, Mary DASG, Ruggeri P, Surico N, Vacca G & Vassanelli C (2001). The role of activation of the renin-angiotensin system on the reflex regional vasoconstriction caused by distension of the uterus in anaesthetized pigs. Auton Neurosci Basic 93, 56-64.
18. Molinari C, Battaglia A, Grossini E, Mary DASG, Vassanelli C & Vacca G (2002). The effect of testosterone on regional blood flow in prepubertal anaesthetized pigs. J Physiol 543, 365-372.
19. Molinari C, Grossini E, Mary DASG & Vacca G (2000). Effect of distension of the gallbladder on PRA in anesthetized pigs. Circulation 101, 2539-2545.
20. Paintal AS (1954). A study of gastric stretch receptors. The role in the peripheral mechanism of satiation of hunger and thirst. J Physiol 126, 255-270.
21. Pals DT & Couch SJ (1993). Renin release induced by losartan (DuP 753), an angiotensin II receptor antagonist. Clin Exp Hypertens 15, 1-13.
22. Rossi P, Andriesse GI, Oey PL, Wieneke GH, Roelofs JMM & Akkermans LMA (1998). Stomach distension increases efferent muscle sympathetic nerve activity and blood pressure in healthy humans. J Neurol Sci 161, 148-155.
23. Vacca G, Battaglia A, Grossini E, Mary DASG & Molinari C (1996a). Reflex coronary vasoconstriction caused by gallbladder distension in anesthetized pigs. Circulation 94, 2201-2209.
24. Vacca G, Battaglia A, Grossini E, Mary DASG, Molinari C & Surico N (1997a). Reflex haemodynamic responses caused by distension of the uterus in anaesthetized pigs. J Auton Nerv Syst 63, 1-11.
25. Vacca G, Battaglia A, Grossini E, Mary DASG, Molinari C & Surico N (1997b). Changes in regional blood flow in response to distension of the uterus in anaesthetised pigs. J Auton Nerv Syst 66, 7-14.
26. Vacca G, Chiorboli E, Grossini E & Papillo B (1994a). The effect of distension of the stomach on PRA in the anesthetized pig. Cardioscience 5, 261-267.
27. Vacca G, Mary DASG, Battaglia A, Grossini E & Molinari C (1996b). The effect of distension of the stomach on peripheral blood flow in anaesthetized pigs. Exp Physiol 81, 385-396.
28. Vacca G, Mary DASG & Vono P (1994b). The effect of distension of the stomach on coronary blood flow in anaesthetized pigs. Pflugers Arch 428, 127-133.
29. Vacca G & Vono P (1993). The primary reflex effects of distension of the stomach on heart rate, arterial pressure and left ventricular contractility in the anaesthetized pig. Pflugers Arch 425, 248-255.