Structure of YM-254890, a novel Gq/11 inhibitor from Chromobacterium sp. QS3666

Tetrahedron

Volumn 59, Issue 25, 2003, Pages 4533-4538

  Taniguchi, Masatoshi ^a   Suzumura, Ken Ichi ^a   Nagai, Koji ^a   Kawasaki, Tomihisa ^a   Saito, Tetsu ^a   Takasaki, Jun ^a   Suzuki, Ken Ichi ^a   Fujita, Shigeo ^a   Tsukamoto, Shin Ichi ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

Cyclic peptide; Depsipeptide; Gq 11 inhibitor; YM 254890

Indexed keywords

3 HYDROXYLEUCINE; 3 PHENYLLACTIC ACID; ACID; AMIDE; AMINO ACID; DEPSIPEPTIDE; FR 900359; LACTIC ACID DERIVATIVE; N METHYLDEHYDROALANINE; N,O DIMETHYLTHREONINE; PROTEIN; PROTEIN G Q 11; PROTEIN INHIBITOR; SOLVENT; UNCLASSIFIED DRUG; YM 254890;

ANALYTIC METHOD; ARTICLE; CHEMICAL BOND; CHEMICAL STRUCTURE; CHROMOBACTERIUM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATION PROCEDURE; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; STEREOCHEMISTRY; STRUCTURE ANALYSIS;

CHROMOBACTERIUM;

EID: 0038512229     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(03)00680-X     Document Type: Article

References (7)

1. Packham M.A. Can. J. Physiol. Pharmacol. 72:1994;278-284.
2. Taniguchi M., Nagai K., Arao N., Kawasaki T., Saito T., Moritani Y., Takasaki J., Hayashi K., Fujita S., Suzuki K., Tsukamoto S. J. Antibiot. 56:2003;358-363.
3. Roy M.C., Ohtani I.I., Ichiba T., Tanaka J., Satari R., Higa T. Tetrahedron. 56:2000;9079-9092.
4. Marfey P. Carlsberg Res. Commun. 49:1984;591-596.
5. Fujioka M., Koda S., Morimoto Y., Biemann K. J. Org. Chem. 53:1988;2820-2825.
6. Miyamae A., Fujioka M., Koda S., Morimoto Y. J. Chem. Perkin Trans. 5. 1989;873-878.
7. Imai K., Wanabe Y. Anal. Chim. Acta. 130:1981;377-383.