ε-amino caproic acid additive decreases fibrin bandage performance in a swine arterial bleeding model

Thrombosis Research

Volumn 108, Issue 5-6, 2002, Pages 341-345

  Rothwell, Stephen W ^a,b   Fudge, James M ^a   Reid, Thomas J ^a   Krishnamurti, Chitra ^a  

^a WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^b UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

Arterial hemorrhage; Fibrin dressing; Fibrinogen; Swine

Indexed keywords

AMINOCAPROIC ACID; FIBRIN; FIBRINOGEN; LYSINE DERIVATIVE; PLASMIN; FIBRIN GLUE; HEMOSTATIC AGENT;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BANDAGE; BLEEDING; CONTROLLED STUDY; FIBRINOGEN BLOOD LEVEL; HEMOSTASIS; MALE; NONHUMAN; PARTIAL THROMBOPLASTIN TIME; PROTHROMBIN TIME; SWINE; THROMBOPLASTIN TIME; ANIMAL; ARTERY; BLOOD CLOTTING; BLOOD CLOTTING TEST; CHEMISTRY; DISEASE MODEL; DRUG EFFECT; INJURY; PROTECTIVE CLOTHING; STANDARD; WOUND HEALING;

6-AMINOCAPROIC ACID; ANIMALS; ARTERIES; BLOOD COAGULATION; BLOOD COAGULATION TESTS; BLOOD LOSS, SURGICAL; DISEASE MODELS, ANIMAL; FIBRIN TISSUE ADHESIVE; HEMORRHAGE; HEMOSTASIS; HEMOSTATIC TECHNIQUES; HEMOSTATICS; MALE; OCCLUSIVE DRESSINGS; SWINE; WOUND HEALING;

EID: 0038506216     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0049-3848(03)00111-7     Document Type: Article

References (17)

1. Holcomb J.B., Pusateri A.E., Hess J.R., Hetz S.P., Harris R.A., Tock B.B.et al. Implications of new dry fibrin sealant technology for trauma surgery. Surg. Clin. North Am. 77(4):1997;943-952.
2. Jackson M.R., Friedman S.A., Carter A.J., Bayer V., Burge J.R., MacPhee M.J.et al. Hemostatic efficacy of a fibrin sealant-based topical agent in a femoral artery injury model: a randomized, blinded, placebo-controlled study. J. Vasc. Surg. 26(2):1997;274-280.
3. Jackson M.R., Taher M.M., Burge J.R., Krishnamurti C., Reid T.J., Alving B.M. Hemostatic efficacy of a fibrin sealant dressing in an animal model of kidney injury. J. Trauma. 45(4):1998;662-665.
4. Holcomb J.B., Pusateri A.E., Harris R.A., Charles N.C., Gomez R.R., Cole J.P.et al. Effect of dry fibrin sealant dressings versus gauze packing on blood loss in grade V liver injuries in resuscitated swine. J. Trauma. 46(1):1999;49-57.
5. Holcomb J.B., Pusateri A.E., Harris R.A., Reid T.J., Beall L.D., Hess J.R.et al. Dry fibrin sealant dressings reduce blood loss, resuscitation volume, and improve survival in hypothermic coagulopathic swine with grade V liver injuries. J. Trauma. 47(2):1999;233-240. [discussion 240-232].
6. Holcomb J., MacPhee M., Hetz S., Harris R., Pusateri A., Hess J. Efficacy of a dry fibrin sealant dressing for hemorrhage control after ballistic injury. Arch. Surg. 133(1):1998;32-35.
7. Scheyer M., Zimmermann G. TachoComb used in endoscopic surgery. Surg. Endosc. 10(5):1996;501-503.
8. Czerny M., Verrel F., Weber H., Muller N., Kircheis L., Lang W.et al. Collagen patch coated with fibrin glue components. Treatment of suture hole bleedings in vascular reconstruction. J. Cardiovasc. Surg. (Torino). 41(4):2000;553-557.
9. Hollaus P., Pridun N. The use of TachoComb in thoracic surgery. J. Cardiovasc. Surg. (Torino). 35(6 Suppl. 1):1994;169-170.
10. Agus G.B., Bono A.V., Mira E., Olivero S., Peilowich A., Homdrum E.et al. Hemostatic efficacy and safety of TachoComb in surgery. Ready to use and rapid hemostatic agent. Int. Surg. 81(3):1996;316-319.
11. Levy J.H. Hemostatic agents and their safety. J. Cardiothorac. Vasc. Anesth. 13(4 Suppl. 1):1999;6-11. [discussion 36-17].
12. Maineri P., Covaia G., Realini M., Caccia G., Ucussich E., Luraschi M.et al. Postoperative bleeding after coronary revascularization. Comparison between tranexamic acid and epsilon-aminocaproic acid. Minerva Cardioangiol. 48(6):2000;155-160.
13. Kallmes D.F., Marx W.F., Jensen M.E., Cloft H.J., Do H.M., Lanzino G.et al. Adjuvant use of epsilon-aminocaproic acid (Amicar) in the endovascular treatment of cranial arteriovenous fistulae. Neuroradiology. 42(4):2000;302-308.
14. Urban M.K., Beckman J., Gordon M., Urquhart B., Boachie-Adjei O. The efficacy of antifibrinolytics in the reduction of blood loss during complex adult reconstructive spine surgery. Spine. 26(10):2001;1152-1157.
15. Glick R., Green D., Ts'ao C., Witt W.A., Yu A.T., Raimondi A.J. High dose ε-aminocaproic acid prolongs the bleeding time and increases rebleeding and intraoperative hemorrhage in patients with subarachnoid hemorrhage. Neurosurgery. 9:1981;398-400.
16. Green D., Ts'ao C.H., Cerullo L., Cohen I., Ruo T.I., Atkinson A.J. Jr. Clinical and laboratory investigation of the effects of ε-aminocaproic acid on hemostasis. J. Lab. Clin. Med. 105:1985;321-327.
17. Munster A.M., Ingemann Jensen J., Bech B., Gram J. Activation of blood coagulation in pigs following lower limb gunshot trauma. Blood Coagul. Fibrinolysis. 12(6):2001;477-485.