메뉴 건너뛰기




Volumn 9, Issue 7, 2003, Pages 2389-2390

Skin as a surrogate tissue for pharmacodynamic end points: Is it deep enough?

Author keywords

[No Author keywords available]

Indexed keywords

6 (4 HYDROXYPHENYL) 4 (ALPHA METHYLBENZYLAMINO) 7H PYRROLO[2,3 D]PYRIMIDINE; BIOLOGICAL MARKER; CANERTINIB; CYCLIN DEPENDENT KINASE INHIBITOR; CYTOTOXIC AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; GEFITINIB; IMATINIB; KI 67 ANTIGEN; MATUZUMAB; MITOGEN ACTIVATED PROTEIN KINASE; MONOCLONAL ANTIBODY; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P27; PROTEIN TYROSINE KINASE INHIBITOR; STAT3 PROTEIN; TRASTUZUMAB;

EID: 0038493878     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Editorial
Times cited : (35)

References (14)
  • 1
    • 0037899935 scopus 로고    scopus 로고
    • Improving the evaluation of new cancer treatments: Challenges and opportunities
    • Rothenberg, M. L., Carbone, D. P., and Johnson, D. H. Improving the evaluation of new cancer treatments: challenges and opportunities. Nat. Rev. Cancer, 3: 303-309, 2003.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 303-309
    • Rothenberg, M.L.1    Carbone, D.P.2    Johnson, D.H.3
  • 2
    • 0037392444 scopus 로고    scopus 로고
    • Issues and progress with protein kinase inhibitors for cancer treatment
    • Dancey, J., and Sausville, E. A. Issues and progress with protein kinase inhibitors for cancer treatment. Nat. Rev. Drug Discov., 2: 296-313, 2003.
    • (2003) Nat. Rev. Drug Discov. , vol.2 , pp. 296-313
    • Dancey, J.1    Sausville, E.A.2
  • 4
    • 0032127350 scopus 로고    scopus 로고
    • Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neuoverexpressing human breast cancer xenografts
    • Baselga, J., Norton, L., Albanell, J., Kim, Y. M., and Mendelsohn, J. Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neuoverexpressing human breast cancer xenografts. Cancer Res., 58: 2825-2831, 1998.
    • (1998) Cancer Res. , vol.58 , pp. 2825-2831
    • Baselga, J.1    Norton, L.2    Albanell, J.3    Kim, Y.M.4    Mendelsohn, J.5
  • 5
    • 0033118889 scopus 로고    scopus 로고
    • Inhibitory effects of combinations of HER-2/neu antibody and chemotherapeutic agents used for the treatment of human breast cancers
    • Pegram, M., Hsu, S., Lewis, G., Pietras, R., Beryt, M., Sliwkowski, M., Coombs, D., Baly, D., Kabbinavar, F., and Slamon, D. Inhibitory effects of combinations of HER-2/neu antibody and chemotherapeutic agents used for the treatment of human breast cancers. Oncogene, 18: 2241-2251, 1999.
    • (1999) Oncogene , vol.18 , pp. 2241-2251
    • Pegram, M.1    Hsu, S.2    Lewis, G.3    Pietras, R.4    Beryt, M.5    Sliwkowski, M.6    Coombs, D.7    Baly, D.8    Kabbinavar, F.9    Slamon, D.10
  • 6
    • 0035418622 scopus 로고    scopus 로고
    • Activated extracellular signal-regulated kinases: Association with epidermal growth factor receptor/transforming growth factor α expression in head and neck squamous carcinoma and inhibition by anti-EGF receptor treatments
    • Albanell, J., Codony-Servat, J., Rojo, F., Del Campo, J. M., Sauleda, S., Raspall, G., Giralt, J., Roselló, J., Nicholson, R. I., Mendelsohn, J., and Baselga, J. Activated extracellular signal-regulated kinases: association with epidermal growth factor receptor/transforming growth factor α expression in head and neck squamous carcinoma and inhibition by anti-EGF receptor treatments. Cancer Res., 61: 6500-6510, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 6500-6510
    • Albanell, J.1    Codony-Servat, J.2    Rojo, F.3    Del Campo, J.M.4    Sauleda, S.5    Raspall, G.6    Giralt, J.7    Roselló, J.8    Nicholson, R.I.9    Mendelsohn, J.10    Baselga, J.11
  • 8
    • 0032546269 scopus 로고    scopus 로고
    • EGF receptor signaling inhibits keratinocyte apoptosis: Evidence for mediation by Bcl-XL
    • Stoll, S., Benedict, M., Mitra, R., Hiniker, A., Elder, J. T., and Nunez, G. EGF receptor signaling inhibits keratinocyte apoptosis: evidence for mediation by Bcl-XL. Oncogene, 16: 1493-1499, 1998.
    • (1998) Oncogene , vol.16 , pp. 1493-1499
    • Stoll, S.1    Benedict, M.2    Mitra, R.3    Hiniker, A.4    Elder, J.T.5    Nunez, G.6
  • 9
    • 0033762498 scopus 로고    scopus 로고
    • The EGF receptor: An essential regulator of multiple epidermal functions
    • Jost, M., Kari, C., and Rodeck, U. The EGF receptor: an essential regulator of multiple epidermal functions. Eur. J. Dermatol., 10: 505-510, 2000.
    • (2000) Eur. J. Dermatol. , vol.10 , pp. 505-510
    • Jost, M.1    Kari, C.2    Rodeck, U.3
  • 11
    • 0005375432 scopus 로고    scopus 로고
    • A Phase I and pharmacological study of intermittent dosing of PKI 166, a novel EGFR tyrosine kinase inhibitor administered orally to patients with advanced cancer
    • Hoeskstra, R. D. H. A Phase I and pharmacological study of intermittent dosing of PKI 166, a novel EGFR tyrosine kinase inhibitor administered orally to patients with advanced cancer. In: AACR-NCI-EORTC 2001.
    • (2001) AACR-NCI-EORTC
    • Hoeskstra, R.D.H.1
  • 13
    • 0037968876 scopus 로고    scopus 로고
    • A Phase I pharmacokinetic (PK) and serial tumor and skin pharmacodynamic (PD) study of weekly, every 2 weeks or every 3 weeks 1-hour (h) infusion EMD72000, an humanized monoclonal anti-epidermal growth factor receptor (EGFR) antibody, in patients (p) with advanced tumors known to overexpress the EGFR
    • Tabernero, J., Rojo, F., Jimenez, E., Montaner, I., Santome, L., Guix, M., Rosen, Kovar, A., Viaplana, I., and Baselga, J. A Phase I pharmacokinetic (PK) and serial tumor and skin pharmacodynamic (PD) study of weekly, every 2 weeks or every 3 weeks 1-hour (h) infusion EMD72000, an humanized monoclonal anti-epidermal growth factor receptor (EGFR) antibody, in patients (p) with advanced tumors known to overexpress the EGFR. Eur. J. Cancer, 38 (Suppl. 7): 69, 2002.
    • (2002) Eur. J. Cancer , vol.38 , Issue.SUPPL. 7 , pp. 69
    • Tabernero, J.1    Rojo, F.2    Jimenez, E.3    Montaner, I.4    Santome, L.5    Guix, M.6    Rosen Kovar, A.7    Viaplana, I.8    Baselga, J.9
  • 14
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase-akt Pathway in human cancer
    • Vivanco, I., and Sawyers, C. L. The phosphatidylinositol 3-kinase-akt Pathway in human cancer. Nat. Rev. Cancer, 2: 489-501, 2002.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.