Mitochondrial DNA replication: What we know

IUBMB Life

Volumn 55, Issue 4-5, 2003, Pages 213-217

  Clayton, David A ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

DNA replication; Mitochondria; mtDNA; Origin; Promoter; Transcription

Indexed keywords

ADENOSINE TRIPHOSPHATE; CIRCULAR DNA; CYTOCHROME C OXIDASE; MITOCHONDRIAL DNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; SINGLE STRANDED DNA;

CIRCULAR DICHROISM; DNA DETERMINATION; DNA ISOLATION; DNA REPLICATION; DNA SEQUENCE; DNA STRAND; DNA STRUCTURE; DNA SYNTHESIS; DNA TRANSCRIPTION; DNA TRANSFER; GENE LOCUS; HUMAN; MOLECULAR MODEL; NONHUMAN; POLYMERASE CHAIN REACTION; REVIEW; TWO DIMENSIONAL GEL ELECTROPHORESIS;

ANIMALS; DNA REPLICATION; DNA, MITOCHONDRIAL;

MAMMALIA;

EID: 0038491235     PISSN: 15216543     EISSN: None     Source Type: Journal    
DOI: 10.1080/1521654031000134824     Document Type: Review

References (20)

1. Radloff, R., Bauer, W., and Vinograd, J. (1967) A dye-buoyant density method for the detection and isolation of closed circular DNA: The closed circular DNA in HeLa cells. Proc. Natl. Acad. Sci. USA 57, 1514-1521.
2. Robberson, D. L., Kasamatsu, H., and Vinograd, J. (1972) Replication of mitochondrial DNA. Circular replicative intermediates in mouse L cells. Proc. Natl. Acad. Sci. USA 69. 737-741.
3. Wolstenholme, D. R., Koike, K. and Cochran-Fouts, P. (1974) Replication of mitochondrial DNA: Replicative forms of molecules from rat tissues and evidence for discontinuous replication. Cold Spring Harbor Symp. Quant. Biol. 38, 267-280.
4. Tapper, D. P. and Clayton. D. A. (1981) Mechanism of replication of human mitochondrial DNA. Localization of the 5′ ends of nascent daughter strands. J. Biol. Chem. 256, 5109-5115.
5. Kang, D., Miyako, K., Kai, Y., Irie, T., and Talzeshige, K. (1997) In vivo determination of replication origins of human mitochondrial DNA by ligation-mediated polymerase chain reaction. J. Biol. Chem. 272, 15275-15279.
6. Bogenhagen, D., Gillum, A. M., Martens, P. A., and Clayton, D. A. (1979) Replication of mouse L-cell mitochondrial DNA. Cold Spring Harbor Symp. Quant. Biol. 43, 253-262.
7. Nass, M. M. K. (1980) Pulse-label analysis and mapping of the two terminal regions of asynchronous complementary strand replication of mitochondrial DNA in transformed hamster cells. J. Mol. Biol. 140, 257-281.
8. Nass, M. M. K. (1980) Analysis of the heavy and light strand origins and the direction of replication of mitochondrial DNA within a detailed physical map of this genome in transformed hamster cells. J. Mol. Biol. 140, 231-256.
9. Diaz, F., Bayona-Bafaluy, M. P., Rana, M., Mora, M., Hao, H., and Moraes, C.T. (2002) Human mitochondrial DNA with large deletions repopulates organelles faster than full-length genomes under relaxed copy number control. Nucl. Acids Res. 30, 4626-4633.
10. Holt, I. J., Lorimer, H. E., and Jacobs, H. T. (2000) Coupled leading-and lagging-strand synthesis of mammalian mitochondrial DNA. Cell 100, 515-524.
11. Yang, M. Y., Bowmaker, M., Reyes, A., Vergani, L., Paolo, A., Gringeri, E., Jacobs, H. T., and Holt, I. J. (2002) Biased incorporation of ribonucleotides on the mitochondrial L-strand accounts for apparent strand-asymmetric DNA replication. Cell 111, 495-505.
12. Brewer, B. J., and Fangman, W. L. (1987) The localization of replication origins on ARS plasmids in S. cerevisiae. Cell 51, 463-471.
13. Grossman, L. I., Watson. R., and Vinograd, J. (1973) The presence of ribonucleotides in mature closed-circular mitochondrial DNA. Proc. Natl. Acad. Sci. USA 70, 3339-3343.
14. Wong-Staal, F., Mendelsohn, J., and Goulian, M. (1973) Ribonucleotides in closed circular mitochondrial DNA from HeLa Cells. Biochem. Biophys. Res. Comm. 53, 140-148.
15. Lonsdale, D., and Jones, I. G. (1978) Localization of the ribonucleotide sites in rat liver mitochondrial DNA. Biochem. J. 169, 79-85.
16. Brennicke, A., and Clayton, D. A. (1981) Nucleotide assignment of alkali-sensitive sites in mouse mitochondrial DNA. J. Biol. Chem. 256, 10613-10617.
17. Margolin, K., Doda, J. N., and Clayton, D. A. (1981) Mechanism of mitochondrial DNA replication in mouse L cells: localization of alkali-sensitive sites at the two origins of replication. Plasmid 6, 332-341.
18. Cerritelli, S. M., Frolova, E. G., Feng, C., Grinberg, A., Love, P. E., and Crouch, R.J. (2003) Failure to produce mitochondrial DNA results in embryonic lethality in Rnaseh I null mice. Mol. Cell 11, 807-815.
19. Clayton, D. A. (1982) Replication of animal mitochondrial DNA. Cell 28, 693-705.
20. Shadel, G. S., and Clayton, D. A. (1997) Mitochondrial DNA maintenance in vertebrates. Annu. Rev. Biochem. 66, 409-435.