Role of nitric oxide in regulating the rat hypothalamic-pituitary-adrenal axis response to endotoxemia

Annals of the New York Academy of Sciences

Volumn 992, Issue , 2003, Pages 72-85

  Rivier, Catherine ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

ACTH; Endotoxemia; HPA axis; Lipopolysaccharide (LPS); Nitric oxide; Rats

Indexed keywords

BRAIN MONOAMINE; CORTICOTROPIN RELEASING FACTOR; CYTOKINE; LIPOPOLYSACCHARIDE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PROSTAGLANDIN; VASOPRESSIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; BRAIN CELL; CELL ACTIVATION; CONCENTRATION RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; CORTICOTROPIN RELEASE; ENDOTOXEMIA; HYPOTHALAMUS; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; MALE; NONHUMAN; RAT; THALAMUS MIDLINE NUCLEUS;

ANIMALIA;

EID: 0038468399     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2003.tb03139.x     Document Type: Conference Paper

References (50)

1. MONCADA, S., R.M.J. PALMER & E.A. HIGGS. 1991. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol. Rev. 43: 109-142.
2. BREDT, D.S. & S.H. SNYDER. 1994. Nitric oxide: a physiologic messenger molecule. Annu. Rev. Biochem. 63: 175-195.
3. AMIR, S. 1995. Nitric oxide signalling in the hypothalamus. In Nitric Oxide in the Nervous System.:151-162. Academic Press Limited. San Diego.
4. BRANN, D. et al. 1997. Gaseous transmitters and neuroendocrine regulation. Neuroendocrinology 65: 385-395.
5. DAWSON, T. & S. SNYDER. 1994. Gases as biological messengers: nitric oxide and carbon monoxide in the brain. J. Neurosci. 14: 5147-5159.
6. SCHUMAN, E. & D. MADISON. 1994. Nitric oxide and synaptic functions. Ann. Rev. Neurosci. 17: 153-183.
7. MOILANEN, E. & H. VAPAATALO. 1995. Nitric oxide in inflammation and immune responses. Ann. Med. 27: 359-367.
8. SNYDER, S.H. & T.M. DAWSON. 1995. Nitric oxide and related substances as neural messengers. In Psychopharmacology: The Fourth Generation of Progress. F.E. Bloom & D.J. Kupfer, Eds.:609-618. Raven Press, Ltd. New York.
9. RIVIER, C. 1998. Role of nitric oxide and carbon monoxide in modulating the ACTH response to immune and non-immune signals. Neuroimmunomodulation 5: 203-213.
10. TURNBULL, A. et al. 1998. Influence of carbon monoxide, and its interaction with nitric oxide, on the ACTH response of the intact rat to a physico-emotional stress. J. Neuroendocrinol. 10: 793-802.
11. RODRIGO, J. et al. 1994. Localization of nitric oxide synthase in the adult rat brain. Phil. Trans. Roy. Soc. Lond. Ser. B - Biol. Sci. 345: 175-221.
12. HÖKFELT, T. et al. 1994. Plasticity of NO synthase expression in the nervous and endocrine systems. Neuropharmacology 33: 1221-1227.
13. TORRES, G., S. LEE & C. RIVIER. 1993. Ontogeny of the rat hypothalamic nitric oxide synthase and colocalization with neuropeptides. Mol. Cell. Neurosci. 4: 155-163.
14. SIAUD, P. et al. 1994. A subpopulation of corticotropin-releasing hormone neurosecretory cells in the paraventricular nucleus of the hypothalamus also contain NADPH-diaphorase. Neurosci. Lett. 170: 51-54.
15. AREVALO, A. et al. 1992. NADPH-diaphorase activity in the hypothalamic magnocellular neurosecretory nuclei of the rat. Brain Res. Bull. 28: 599-603.
16. SANCHEZ, F. et al. 1994. Coexistence of NADPH-diaphorase with vasopressin and oxytocin in the hypothalamic magnocellular neurosecretory nuclei of the rat. Cell Tissue Res. 276: 31-34.
17. VINCENT, S.R. 1995. Localization of nitric oxide neurons in the central nervous system. In Nitric Oxide in the Nervous System. S.R. Vincent, Ed.:83-102. Academic Press Ltd.
18. RIVIER, C. & G. SHEN. 1994. In the rat, endogenous nitric oxide modulates the response of the hypothalamic-pituitary-adrenal axis to interleukin-1β, vasopressin and oxytocin. J. Neurosci. 14: 1985-1993.
19. RIVIER, C. 1995. Blockade of nitric oxide formation augments adrenocorticotropin released by blood-borne interleukin-1β: role of vasopressin, prostaglandins, and α1-adrenergic receptors. Endocrinology 136: 3597-3603.
20. TURNBULL, A.V. & C. RIVIER. 1996. Corticotropin-releasing factor, vasopressin and prostaglandins mediate, and nitric oxide restrains, the hypothalamic-pituitary-adrenal response to acute local inflammation in the rat. Endocrinology 137: 455-463.
21. KIM, C.K. & C. RIVIER. 1998. Influence of nitric oxide synthase inhibitors on the ACTH and cytokine responses to peripheral immune signals. J. Neuroendocrinol. 10: 353-362.
22. RIVIER, C. 1994. Endogenous nitric oxide participates in the activation of the hypothalamic-pituitary-adrenal axis by noxious stimuli. Endocr. J. 2: 367-373.
23. LEE, S. & C. RIVIER. 1998. Interaction between corticotropin-releasing factor and nitric oxide in mediating the response of the rat hypothalamus to immune and non-immune stimuli. Mol. Brain Res. 57: 54-62.
24. LEE, S. & C. RIVIER. 1998. The intracerebroventricular injection of the nitric oxide donor 3-morpholinosydnonimine (SIN-1) activates the rat hypothalamic-pituitary-adrenal axis [abstr.]. 28th Annual Meeting of the Society for Neuroscience.
25. BAUMANN, H. & J. GAULDIE. 1994. The acute phase response. Immunol. Today 15: 74-80.
26. SHALABY, M.R. et al. 1989. Endotoxin, tumor necrosis factor-α and interleukin 1 induce interleukin 6 production in vivo. Clin. Immunol. Immunopathol. 53: 488-498.
27. TAKAO, T. et al. 1997. Endotoxin induced increases in rat plasma pituitary-adrenocortical hormones are better reflected by alterations in tumor necrosis factor α than interleukin-1β. Life Sci. 61: PL263-PL268.
28. GIVALOIS, L. et al. 1994. Temporal cascade of plasma level surges in ACTH, corticosterone, and cytokines in endotoxin-challenged rats. Am. J. Physiol. 267: R164-R170.
29. BESEDOVSKY, H.O. & A. DELREY. 1992. Immuno-neuroendocrine circuits: integrative role of cytokines. Front. Neuroendocrinol. 13: 61-94.
30. DELREY, A. & H.O. BESEDOVSKY. 1992. Metabolic and neuroendocrine effects of proinflammatory cytokines. Eur. J. Clin. Invest. (Suppl.) 22: 10-15.
31. KAKUCSKA, I. et al. 1993. Endotoxin-induced corticotropin-releasing hormone gene expression in the hypothalamic paraventricular nucleus is mediated centrally by interleukin-1. Endocrinology 133: 815-821.
32. RIVEST, S., N. LAFLAMME & R. NAPPI. 1995. Immune challenge and immobilization stress induce transcription of the gene encoding the CRF receptor in selective nuclei of the rat hypothalamus. J. Neurosci. 15: 2680-2695.
33. LACROIX, S. & S. RIVEST. 1996. Role of cyclo-oxygenase pathways in the stimulatory influence of immune challenge on the transcription of a specific CRF receptor subtype in the rat brain. J. Chem. Neuroanat. 10: 53-71.
34. LACROIX, S. & S. RIVEST. 1997. Functional circuitry in the brain of immune-challenged rats: partial involvement of prostaglandins. J. Comp. Neurol. 387: 307-324.
35. LACROIX, S. & S. RIVEST. 1998. Effect of acute systemic inflammatory response and cytokines on the transcription of the genes encoding cyclooxygenase enzymes (COX-1 and COX-2) in the rat brain. Neurochemistry 70: 452-466.
36. DUNN, A. 1995. Interactions between the nervous system and the immune system: implications for psychopharmacology. In Psychopharmacology. F.E. Bloom & D.J. Kupfer, Eds.:719-731. Raven Press, New York.
37. LAVICKY, J. & A.J. DUNN. 1995. Endotoxin administration stimulates cerebral catecholamine release in freely moving rats as assessed by microdialysis. J. Neurosci. Res. 40: 407-413.
38. TURNBULL, A.V.T. & C.L. RIVIER. 1999. Regulation of the hypothalamo-pituitary-adrenal (HPA) axis by cytokines: actions and mechanisms of action. Physiol. Rev. 79: 1-71.
39. WAN, W.H. et al. 1994. Neural and biochemical mediators of endotoxin and stress-induced c-fos expression in the rat brain. Brain Res. Bull. 34: 7-14.
40. LI, H.-Y. & P.E. SAWCHENKO. 1998. Hypothalamic effector neurons and extended circuitries activated in "neurogenic" stress: a comparison of footshock effects exerted acutely, chronically, and in animals with controlled glucocorticoid levels. J. Comp. Neurol. 393: 244-266.
41. LEE, S. & C. RIVIER. 1994. Hypophysiotropic role and hypothalamic gene expression of corticotropin-releasing factor and vasopressin in rats injected with interleukin-1β systemically or into the brain ventricles. J. Neuroendocrinol. 6: 217-224.
42. KIM, C. & C. RIVIER. 2000. Nitric oxide and carbon monoxide have a stimulatory role in the hypothalamic-pituitary-adrenal response to physico-emotional stressors in rats. Endocrinology 141: 2244-2253.
43. KORNREICH, W.D. et al. 1992. Alanine series of ovine corticotropin releasing factor (oCRF): a structure-activity relationship study. J. Med. Chem. 35: 1870-1876.
44. KOOB, G.F. et al. 1993. The role of corticotropin-releasing factor in behavioural responses to stress. Ciba Foundation Symposium, No. 172. In Corticotropin-Releasing Factor. D.J. Chadwick, J. Marsh & K. Ackrill, Eds.:277-295. John Wiley & Sons. New York, NY.
45. KOOB, G.F. & S.C. HEINRICHS. 1999. A role for corticotropin releasing factor and urocortin in behavioral responses to stressors. Brain Res. 848: 141-152.
46. TURNBULL, A. & C. RIVIER. 1998. Intracerebroventricular passive immunization. I. The effect of intracerebroventricular administration of an antiserum to tumor necrosis factor-α on the plasma adrenocorticotropin response to lipopolysaccharide in rats. Endocrinology 139: 119-127.
47. TURNBULL, A. & C. RIVIER. 1998. Intracerebroventricular passive immunization. II. Intracerebroventricular infusion of neuropeptide antisera can inhibit neuropeptide signaling in peripheral tissues. Endocrinology 139: 128-136.
48. VALLIÈRES, L. & S. RIVEST. 1997. Regulation of the genes encoding interleukin-6, its receptor, and gp130 in the rat brain in response to the immune activator lipopolysaccharide and the proinflammatory cytokine interleukin-1β. J. Neurochem. 69: 1668-1683.
49. LEE, S., C. KIM & C. RIVIER. 1999. Nitric oxide stimulates ACTH secretion and the transcription of the genes encoding for NGFI-B, corticotropin-releasing factor, corticotropin-releasing factor receptor type 1 and vasopressin in the hypothalamus of the intact rat. J. Neurosci. 19: 7640-7647.
50. RIVIER, C. 1999. Gender, sex steroids, corticotropin-releasing factor, nitric oxide and the HPA response to stress. Pharmacol. Biochem. Behav. 64: 739-751.