Clinical relevance of reverse transcriptase-polymerase chain reaction for the detection of axillary lymph node metastases in breast cancer

Annals of Surgical Oncology

Volumn 10, Issue 2, 2003, Pages 117-125

  Sakaguchi, Masahiro ^a   Virmani, Arvind ^a   Dudak, Marla W ^a   Peters, George N ^a   Leitch, A Marilyn ^a   Saboorian, Hossein ^a   Gazdar, Adi F ^a   Euhus, David M ^a,b  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Breast cancer; Cytokeratin 19; EGP 2; RT PCR; Sentinel nodes; Survival

Indexed keywords

BETA1 INTEGRIN; CYTOKERATIN 19; GLYCOPROTEIN; KERATIN;

ADULT; AGED; ARTICLE; AXILLARY LYMPH NODE; BREAST CANCER; BREAST TUMOR; CANCER STAGING; CANCER SURVIVAL; COMPARATIVE STUDY; FEMALE; FOLLOW UP; HISTOLOGY; HUMAN; HUMAN TISSUE; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MASTECTOMY; PHENOTYPE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE SECTION; TUMOR DIAGNOSIS; AXILLA; DISEASE FREE SURVIVAL; LYMPH NODE; MIDDLE AGED; PATHOLOGY; SENTINEL LYMPH NODE BIOPSY;

ADULT; AGED; AGED, 80 AND OVER; AXILLA; BREAST NEOPLASMS; DISEASE-FREE SURVIVAL; FEMALE; GLYCOPROTEINS; HUMANS; KERATINS; LYMPH NODES; LYMPHATIC METASTASIS; MIDDLE AGED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SENTINEL LYMPH NODE BIOPSY;

EID: 0038460325     PISSN: 10689265     EISSN: None     Source Type: Journal    
DOI: 10.1245/ASO.2003.01.010     Document Type: Article

References (38)

1. Rosen PP, Groshen S, Saigo PE, Kinne DW, Hellman S. A long-term follow-up study of survival in stage I (T1N0M0) and stage II (T1N1M0) breast carcinoma. J Clin Oncol 1989;7:355-66.
2. Cote RJ, Peterson HF, Chaiwun B, et al. Role of immunohistochemical detection of lymph node metastases in management of breast cancer. Lancet 1999;354:896-900.
3. International (Ludwig) Breast Cancer Study Group. Prognostic importance of occult axillary lymph node micrometastases from breast cancers. Lancet 1990;335:1565-8.
4. Wilkenson EJ, Lawrence L, Hause RG, et al. Occult axillary lymph node metastases in invasive breast carcinoma: characteristics of the primary tumor and significance of the metastases. Pathol Annu 1982;17:67-90.
5. Giuliano AE, Dale PS, Turner RR, Morton DL, Evans SW, Krasne DL. Improved axillary staging of breast cancer with sentinel lymphadenectomy. Ann Surg 1995;222:394-401.
6. Traweek ST, Liu J, Battifora H. Keratin gene expression in non-epithelial tissues. Am J Pathol 1993;142:1111-8.
7. Latza U, Niedobitek G, Schwarting R, Nekarda H, Stein H. Ber-Ep4: new monoclonal antibody which distinguishes epithelia from mesothelial. J Clin Pathol 1990;43:213-9.
8. Osborne MP, Asina S, Wong GY, et al. Immunofluorescent monoclonal antibody detection of breast cancer in bone marrow: sensitivity in a model system. Cancer Res 1989;49:2510-3.
9. Cote RJ, Rosen PP, Hakes TB, et al. Monoclonal antibodies detect occult breast cancer metastases in the bone marrow of patients with early stage disease. Am J Surg Pathol 1988;12:333-40.
10. Noguchi S, Aihara T, Nakamori S, et al. The detection of breast carcinoma micrometastases in axillary lymph nodes by means of reverse transcriptase-polymerase chain reaction. Cancer 1994;74:1595-600.
11. Nwariaku F, Euhus DM, Beitsch PD, et al. Sentinel lymph node biopsy: an alternative to elective axillary dissection for breast cancer. Am J Surg Pathol 1998;176:529-31.
12. Gazdar AF, Oie HK. Re: Martin Brower et al. Growth of cell lines and clinical specimens of human non-small cell lung cancer in a serum-free defined medium. Cancer Res 1986;46:6011-2.
13. 12a. Sakaguchi M, Virmani AK, Ashfaq R, et al. Development of a sensitive, specific PCR-based assay for epithelial tumor cells in effusions. Br J Cancer 1999;79:416-22.
14. Greenwood M. The Errors of Sampling Survivorship Tables (Appendix 1. Reports on Public Health and Statistical Subjects, vol 33). London: His Majesty's Stationary Office, 1926.
15. Janicke F, Prechtl A, Thomssen C, et al. Randomized adjuvant chemotherapy trial in high-risk, lymph node negative breast cancer patients identified by urokinase-type plasminogen activator and plasminogen activator inhibitor type 1. J Natl Cancer Inst 2001;93:913-20.
16. Redding WH, Monaghan P, Imrie SF, et al. Detection of micrometastases in patients with primary breast cancer. Lancet 1983;2:1271-4.
17. Shammas FV, Van Eekelen JAM, Wee L, Heikkila R, Osland A. Sensitive and quantitative one step polymerase chain reaction using capillary electrophoresis and fluorescence detection for measuring cytokeratin 19 expression. Scand J Clin Lab Invest 1999;59:635-42.
18. Kim HK, Park IA, Heo DS, et al. Cyclin E overexpression as an independent risk factor of visceral relapse in breast cancer. Eur J Surg Oncol 2001;27:464-71.
19. Donnellan R, Kleinschmidt I, Chetty R. Cyclin E immunoexpression in breast ductal carcinoma: pathologic correlations and prognostic implications. Hum Pathol 2001;32:89-94.
20. Giuliano AE, Haigh PI, Brennan MB, et al. Prospective observational study of sentinel lymphadenectomy without further axillary dissection in patients with sentinel node-negative breast cancer. J Clin Oncol 2000;18:2553-9.
21. de Mascarel I, Bonichon F, Coindre JM, Trojani M. Prognostic significance of breast cancer axillary lymph node micrometastases assessed by two special techniques: reevaluation with longer follow-up. Br J Cancer 1992;66:523-7.
22. Savtchenko ES, Schiff TA, Jiang CK, Freedberg IM, Blumenberg M. Embryonic expression of the human 40-kD keratin: evidence from a processed pseudogene sequence. Am J Hum Genet 1988;43:630-7.
23. Schoenfeld A, Luqmani Y, Smith D, et al. Detection of breast cancer micrometastases in axillary lymph nodes by using polymerase chain reaction. Cancer Res 1994;54:2986-90.
24. Ruud P, Fodstad O, Hovig E. Identification of a novel cytokeratin 19 pseudogene that may interfere with reverse transcriptase-polymerase chain reaction assays used to detect metastatic tumor cells. Int J Cancer 1999;80:119-25.
25. Mitas M, Mikhitarian K, Walters C, et al. Quantitative real-time RT-PCR detection of breast cancer micrometastasis using a multigene marker panel. Int J Cancer 2001;93:162-71.
26. Youngson BJ, Cranor M, Rosen PP. Epithelial displacement in surgical breast specimens following needling procedures. Am J Surg Pathol 1994;18:896-903.
27. Youngson BJ, Liberman L, Rosen PP. Displacement of carcinomatous epithelium in surgical breast specimens following stereotactic core biopsy. Am J Clin Pathol 1995;103:598-602.
28. Carter BA, Jensen RA, Simpson JF, Page DL. Benign transport of breast epithelium into axillary nodes after biopsy. Am J Clin Pathol 2000;113:259-65.
29. Masuda N, Tamaki Y, Sakita I, et al. Clinical significance of micrometastases in axillary lymph nodes assessed by reverse transcription- polymerase chain reaction in breast cancer patients. Clin Cancer Res 2000;6:4176-85.
30. Noguchi S, Aihara T, Motomura K, Inaji H, Imaoka S, Koyama H. Histologic characteristics of breast cancers with occult lymph node metastases detected by keratin 19 mRNA reverse transcriptase-polymerase chain reaction. Cancer 1996;78:1235-40.
31. Bostick PJ, Huynh KT, Sarantou T, et al. Detection of metastases in sentinel lymph nodes of breast cancer patients by multiple-marker RT-PCR. Int J Cancer 1998;79:645-51.
32. Manzotti M, Dell'Orto P, Maisonneuve P, Zurrida S, Mazzarol G, Viale G. Reverse transcription-polymerase chain reaction assay for multiple mRNA markers in the detection of breast cancer metastases in sentinel lymph nodes. Int J Oncol 2001;95:307-12.
33. Lockett MA, Baron PL, O'Brien PH, et al. Detection of occult breast cancer micrometastases in axillary lymph nodes using a multimarker reverse transcriptase-polymerase chain reaction panel. J Am Coll Surg 1998;187:9-16.
34. Noguchi S, Aihara T, Motomura K, Inaji H, Imaoka S, Koyama H. Detection of breast cancer micrometastases in axillary lymph nodes by means of reverse transcriptase-polymerase chain reaction. Comparison between MUC1 mRNA and keratin 19 mRNA amplification. Am J Pathol 1996;148:649-56.
35. Schoenfeld A, Luqmani Y, Sinnett HD, Shousha S, Coombes RC. Keratin 19 mRNA measurement to detect micrometastases in lymph nodes in breast cancer patients. Br J Cancer 1996;74:1639-42.
36. Hoon DSB, Sarantou T, Doi F, et al. Detection of metastatic breast cancer by beta-hCG polymerase chain reaction. Int J Cancer 1996;69:369-74.
37. Aihara T, Fujiwara Y, Ooka M, Sakita I, Tamaki Y, Monden M. Mammoglobin B as a novel marker for detection of breast cancer micrometastases in axillary lymph nodes by reverse transcription-polymerase chain reaction. Br Cancer Res Treat 1999;58:137-40.
38. Kataoka A, Mori M, Sadanage N, et al. RT-PCR detection of breast cancer cells in sentinel lymph nodes. Int J Oncol 2000;16:1147-52.