Mouse NG2+ oligodendrocyte precursors express mRNA for proteolipid protein but not its DM-20 variant: A study of laser microdissection-captured NG2+ cells

Journal of Neuroscience

Volumn 23, Issue 11, 2003, Pages 4401-4405

  Ye, Ping ^a   Bagnell, Robert ^a,b   D'Ercole, A Joseph ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

DM 20; Gene expression; LCM; MBP; NG2; Oligodendrocyte precursor; PLP

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA; MYELIN BASIC PROTEIN; PROTEOLIPID PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ANTIGEN SPECIFICITY; ARTICLE; CELL TYPE; CENTRAL NERVOUS SYSTEM; DNA SEQUENCE; GENE EXPRESSION; LASER CAPTURE MICRODISSECTION; MOUSE; NERVE CELL; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SPLICING; STEM CELL;

EID: 0038457566     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-11-04401.2003     Document Type: Article

References (30)

1. Campagnoni AT, Roth HJ, Pretorius PJ, Campagnoni CW (1989) Expression of myelin basic protein genes in the developing mouse brain. In: Developmental neurobiology (Evrard P, Minkowski A, eds), pp 95-109. New York: Nestec.
2. Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159.
3. Dawson MR, Levine JM, Reynolds R (2000) NG2-Expressing cells in the central nervous system: are they oligodendroglial progenitors? J Neurosci Res 61:471-479.
4. Diers-Fenger M, Kirchhoff F, Kettenmann H, Levine JM, Trotter J (2001) AN2/NG2 protein-expressing glial progenitor cells in the murine CNS: isolation, differentiation, and association with radial glia. Glia 34:213-228.
5. Fujita N, Sato S, Kurihara T, Kuwano R, Sakimura K, Inuzuka T, Takahashi Y, Miyatake T (1989) cDNA cloning of mouse myelin-associated glycoprotein: a novel alternative splicing pattern. Biochem Biophys Res Commun 165:1162-1169.
6. Hirano M, Goldman JE (1988) Gliogenesis in rat spinal cord: evidence for origin of astrocytes and oligodendrocytes from radial precursors. J Neurosci Res 21:155-167.
7. Hudson LD, Berndt JA, Puckett C, Kozak CA, Lazzarini RA (1987) Aberrant splicing of proteolipid protein mRNA in the dysmyelinating jimpy mutant mouse. Proc Natl Acad Sci USA 84:1454-1458.
8. Ikenaka K, Kagawa T, Mikoshiba K (1992) Selective expression of DM-20, an alternatively spliced myelin proteolipid protein gene product, in developing nervous system and in nonglial cells. J Neurochem 58:2248-2253.
9. Inuzuka T, Fujita N, Sato S, Baba H, Nakano R, Ishiguro H, Miyatake T (1991) Expression of the large myelin-associated glycoprotein isoform during the development in the mouse peripheral nervous system. Brain Res 562:173-175.
10. Keirstead HS, Levine JM, Blakemore WF (1998) Response of the oligodendrocyte progenitor cell population (defined by NG2 labelling) to demyelination of the adult spinal cord. Glia 22:161-170.
11. Lai C, Brow MA, Nave KA, Noronha AB, Quarles R, Bloom FE, Milner RD, Sutcliffe JG (1987) Two forms of 1B236/myelin-associated glycoprotein, a cell adhesion molecule for postnatal neural development, are produced by alternative splicing. Proc Natl Acad Sci USA 84:4337-4341.
12. Levison SW, Goldman JJ (1993) Both oligodendrocytes and astrocytes develop from progenitors in the subventricular zone of postnatal rat forebrain. Neuron 10:201-212.
13. Mallon BS, Shick HE, Kidd GJ, Macklin WB (2002) Proteolipid promoter activity distinguishes two populations of NG2-positive cells throughout neonatal cortical development. J Neurosci 22:876-885.
14. Mason JL, Ye P, Suzuki K, D'Ercole AJ, Matsushima GK (2000) Insulin-like growth factor-1 inhibits mature oligodendrocyte apoptosis during primary demyelination. J Neurosci 20:5703-5708.
15. Morell P, Greenfield S, Costantino-Ceccarini E, Wisniewski H (1972) Changes in the protein composition of mouse brain myelin during development. J Neurochem 19:2545-2554.
16. Nadon NL, Miller S, Draeger K, Salvaggio M (1997) Myelin proteolipid DM20: evidence for function independent of myelination. Int J Dev Neurosci 15:285-293.
17. Nave KA, Lai C, Bloom FE, Milner RJ (1987) Splice site selection in the proteolipid protein (PLP) gene transcript and primary structure of the DM-20 protein of central nervous system myelin. Proc Natl Acad Sci USA 84:5665-5669.
18. Nishiyama A, Lin XH, Giese N, Heldin CH, Stallcup WB (1996) Colocalization of NG2 proteoglycan and PDGF α-recepto on O2A progenitor cells in the developing rat brain. J Neurosci Res 43:299-314.
19. + glial cells are distinct from resting and activated microglia. J Neurosci Res 48:299-312.
20. Pedraza L, Frey AB, Hempstead BL, Colman DR, Salzer JL (1991) Differential expression of MAG isoforms during development. J Neurosci Res 29:141-148.
21. Raff MC (1989) Glial cell diversification in the rat optic nerve. Science 243:1450-1455.
22. Reynolds R, Hardy R (1997) Oligodendroglial progenitors labeled with the 04 antibody persist in the adult rat cerebral cortex in vivo. J Neurosci Res 47:455-470.
23. Schindler P, Luu B, Sorokine O, Trifilieff E, Van Dorsselaer A (1990) Developmental study of proteolipids in bovine brain: a novel proteolipid and DM-20 appear before proteolipid protein (PLP) during myelination. J Neurochem 55:2079-2085.
24. Stallcup WB, Beasley L (1987) Bipotential glial precursor cells of the optic nerve express the NG2 proteoglycan. J Neurosci 7:2737-2744.
25. Trapp BD, Nishiyama A, Cheng D, Macklin W (1997) Differentiation and death of premyelinating oligodendrocytes in developing rodent brain. J Cell Biol 137:459-468.
26. Woodruff RH, Tekki-Kessaris N, Stiles CD, Rowitch DH, Richardson WD (2001) Oligodendrocyte development in the spinal cord and telencephalon: common themes and new perspectives. Int J Dev Neurosci 19:379-385.
27. Ye P, Kanoh M, Zhu W, Laszkiewicz I, Royland JE, Wiggins RC, Konat G (1992) Cyclic AMP-induced upregulation of proteolipid protein and myelin associated glycoprotein gene expression in C6 cells. J Neurosci Res 37:683-690.
28. Ye P, Carson J, D'Ercole AJ (1995) In vivo actions of insulin-like growth factor-I (IGF-I) on brain myelination: studies of IGF-I and IGF binding protein-1 (IGFBP-1) transgenic mice. J Neurosci 15:7344-7356.
29. Ye P, Lee KH, D'Ercole AJ (2000) Insulin-like growth factor-I (IGF-I) protects myelination from undernutritional insult: studies of transgenic mice overexpressing IGF-I in brain. J Neurosci Res 62:700-708.
30. Ye P, Li L, Richards RG, DiAugustine RP, D'Ercole AJ (2002) Myelination is altered in insulin-like growth factor-I null mutant mice. J Neurosci 22:6041-6051.