Unbound valproate fraction in plasma and subcutaneous microdialysate in steady state and after a single dose in humans

Therapeutic Drug Monitoring

Volumn 25, Issue 3, 2003, Pages 378-383

  Lindberger, Martin ^a   Tomson, Torbjörn ^a   Ståhle, Lars ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Microdialysis; Protein binding; Single dose; Steady state; Valproate

Indexed keywords

VALPROIC ACID;

ADULT; ARTICLE; BINDING AFFINITY; CLINICAL ARTICLE; CONTROLLED STUDY; DIALYSATE LEVEL; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG TRANSFORMATION; FEMALE; HUMAN; MALE; MICRODIALYSIS; PRIORITY JOURNAL; SINGLE DRUG DOSE; STEADY STATE;

ADULT; AGED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FEMALE; HUMANS; LEAST-SQUARES ANALYSIS; MALE; MICRODIALYSIS; MIDDLE AGED; PROTEIN BINDING; VALPROIC ACID;

EID: 0038442671     PISSN: 01634356     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007691-200306000-00020     Document Type: Article

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