Binding, internalization and degradation of EGF-dextran conjugates in two human bladder-cancer cell lines

International Journal of Cancer

Volumn 70, Issue 4, 1997, Pages 383-389

  Sjöström, Anna ^a   Bue, Peter ^a   Malmström, Per Uno ^a   Nilsson, Sten ^a   CarlssoN', Jörgen ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

DEXTRAN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR DEXTRAN; EPIDERMAL GROWTH FACTOR DEXTRAN I 125; EPIDERMAL GROWTH FACTOR RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; BLADDER CANCER; CANCER RADIOTHERAPY; CONTROLLED STUDY; HUMAN; HUMAN CELL; PHAGOCYTOSIS; PRIORITY JOURNAL; TUMOR CELL LINE;

CELL MEMBRANE; DEXTRANS; DRUG COMBINATIONS; EPIDERMAL GROWTH FACTOR; HUMANS; IODINE RADIOISOTOPES; MOLECULAR WEIGHT; RECEPTOR, EPIDERMAL GROWTH FACTOR; TIME FACTORS; TUMOR CELLS, CULTURED; URINARY BLADDER NEOPLASMS;

EID: 0038432635     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19970207)70:4<383::AID-IJC2>3.0.CO;2-S     Document Type: Article

References (20)

1. ANDERSSON, A., CAPALA, J. and CARLSSON, J., Effects of EGF-dextrantyrosine-131I conjugates on the clonogenic survival of cultured glioma cells. J. Neuro-Oncol., 14, 213-223 (1992).
2. ANDERSSON, A., HOLMBERG, A., CARLSSON, J., CARLSSON, J., PONTÉN, J. and WESTERMARK, B., Binding of epidermal growth-faetor-dextran conjugates to cultured glioma cells. Int. J. Cancer, 47, 439-144 (1991).
3. BROCKHOFF, G., HOFSTAEDTER, F. and KNEUCHEL, R., Flow cytometric detection and quantitation of the epidermal growth factor receptor in comparison to Scatchard analysis in human bladder carcinoma cell lines. Cytometry, 17, 75-83 (1994).
4. GOLDENBERG, D.M., Carcinoembryonic antigen as a target cancer antigen for radiolabeled antibodies: prospects for cancer imaging and therapy. Tumor Biol, 16, 62-73 (1995).
5. GORGUOLIS, V.G., BARBATIS, C., POULIAS, I. and KARAMERIS, A.M., Molecular and immunohistochemical evaluation of epidermal growth factor receptor and c-erbE-2 gene product in transitional cell carcinomas of the urinary bladder: a study in Greek patients. Mod. Pathol., 8, 758-764 (1995).
6. 125I-epidermal growth factor in BALB 3T3 cells. J. biol. Chem., 225, 1239-1241 (1980).
7. HARNEY, J.V., LIEBERT, M., WEDEMEYER, G., WASHINGTON, R., STEIN, J., BUCHBAUM, D., STEPLEWSKI, Z. and GROSSMAN, H.B., The expression of epidermal growth factor receptor in human bladder cancer: potential use in radioimnumoscintigraphy. Int. J. Urol., 146, 227-231 (1991).
8. JAMES, K., Human monoclonal antibodies and engineered antibodies in the management of cancer. Semin. Cancer Biol., 1, 243-253 (1990).
9. LIEBERT, M., Growth factors in bladder cancer. World J. Urol., 13, 349-355 (1995).
10. MELLON, K., WRIGHT, C., KELLY, P., WILSON HORNE, C.H. and NEAL, D.E., Bladder cancer: long-terin outcome related to epidermal growth factor receptor status in bladder cancer. J. Urol, 153, 919-925 (1995).
11. MENDELSOHN, J., Growth factor receptors as targets for antitumor therapy with monoclonal antibodies. Monoclonal. Antibody Ther., 45, 147-160 (1988).
12. MESSING, E.M., Clinical implications of the expression of epidermal growth factor receptor in human transitional cell carcinoma. Cancer Res., 50, 2530-2537 (1990).
13. NEAL, D.E. and MELLON, K., Epidermal growth factor receptor and bladder cancer: a review. Urol, int., 48, 365-371 (1992).
14. NEAL, D.E., SHARPLES, L., SMITH, K., FHNNEEEY, J., HALE, R.R. and HARRIS, A.L., The epidermal growth factor and the prognosis of bladder cancer. Cancer, 65, 1619-1625 (1990).
15. OLSSON, P., LINDSTRÖM. A. and CARLSSON, J., Internalization and excretion of epidermal growth factor-dextran-associated radioactivity in cultured human squamous-carcinoma cells. Int. J. Cancer, 56, 529 (1994).
16. SAUTER, G., HAYLEY, J., CHEW, K., KERSCHMANN, R., MOORE, D., CARROLL, P., MUCH, H., GUDAT, F., MINATSCH, M.J. and WAEDMAN, F., Epidermal growth factor receptor expression is associated with rapid tumor proliferation in bladder cancer. Int. J. Cancer, 57, 508-514 (1994).
17. SCHACHT, E.S., Dextran and inulin as carriers for bioactive materials. Faculty of Science. University of Ghent. Belgium (1988).
18. TODDERUD, G. and CARPENTER, G., Epidermal growth factor: the receptor and its function. BioFactors, 2, 11 (1989).
19. 131I. Radiother. Oncol., 11, 133-142 (1988).
20. WOOD, D.P., FAIR, W.R. and CHANGANTI, R.S.K., Evaluation of epidermal growth factor DNA amplification and mRNA expression in bladder cancer. J. Urol., 147, 274-277 (1992).