Functional tolerance and blockade of long-term depression at synapses in the nucleus accumbens after chronic cannabinoid exposure

Journal of Neuroscience

Volumn 23, Issue 12, 2003, Pages 4815-4820

  Hoffman, Alexander F ^a   Oz, Murat ^a   Caulder, Tara ^a   Lupica, Carl R ^a,b  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^b NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

Author keywords

Drug abuse; Marijuana; Nucleus accumbens; Synaptic plasticity; Tolerance; 9 THC

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; 4 AMINOBUTYRIC ACID RECEPTOR; CANNABINOID; CANNABINOID RECEPTOR AGONIST; CANNABINOID RECEPTOR ANTAGONIST; CANNABIS; DRONABINOL; DRUG VEHICLE; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; GLUTAMATE RECEPTOR; MU OPIATE RECEPTOR AGONIST; NALOXONE; OPIATE; RIMONABANT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CANNABIS ADDICTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CROSS TOLERANCE; DRUG EFFECT; DRUG EXPOSURE; DRUG SENSITIVITY; ELECTROPHYSIOLOGY; ELECTROSTIMULATION; GABAERGIC TRANSMISSION; LONG TERM EXPOSURE; MALE; NERVE CELL PLASTICITY; NONHUMAN; NUCLEUS ACCUMBENS; POSTSYNAPTIC POTENTIAL; PRIORITY JOURNAL; RAT; SYNAPSE; SYNAPTIC INHIBITION; SYNAPTIC TRANSMISSION;

EID: 0038417099     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-12-04815.2003     Document Type: Article

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