Enantioconvergent synthesis of (-)-(2R,5S)-1-allyl-2,5-dimethylpiperazine, an intermediate to δ-opioid receptor ligands

Journal of Organic Chemistry

Volumn 68, Issue 10, 2003, Pages 3976-3980

  Janetka, James W ^a,b   Furness, M Scott ^a,c   Zhang, Xiaoyan ^a,d   Coop, Andrew ^a,e   Folk, John E ^a   Mattson, Mariena V ^a   Jacobson, Arthur E ^a   Rice, Kenner C ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b ASTRAZENECA   (United Kingdom)

^c CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^d R W JOHNSON PHARMACEUTICAL RES I   (United States)

^e UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL LABORATORIES; CHROMATOGRAPHIC ANALYSIS; SYNTHESIS (CHEMICAL);

LIGANDS;

AMINES;

1 ALLYL 2,5 DIMETHYLPIPERAZINE; LIGAND; MU OPIATE RECEPTOR; PIPERAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINOCICEPTION; ARTICLE; CHROMATOGRAPHY; DERIVATIZATION; DISCRIMINATIVE STIMULUS; DRUG DEPENDENCE; DRUG RECEPTOR BINDING; ENANTIOMER; MOLECULAR INTERACTION; REINFORCEMENT; STIMULUS RESPONSE; SYNTHESIS;

EID: 0038413943     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo0300385     Document Type: Article

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