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Volumn 3, Issue 6, 2001, Pages 477-483

3,4-methylenedioxymethamphetamine (mdma): A review

Author keywords

Ecstasy; MDEA; MDMA; Positron Emission Tomography; Single Photon Emission Compute Tomography

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; PSYCHEDELIC AGENT; SEROTONIN RECEPTOR;

EID: 0038407836     PISSN: 15233812     EISSN: 15351645     Source Type: Journal    
DOI: 10.1007/s11920-001-0041-y     Document Type: Review
Times cited : (18)

References (80)
  • 1
    • 85130831329 scopus 로고    scopus 로고
    • This survey of school age students found that from 1999 to 2000, Ecstasy use increased in eighth-graders and 12th-graders from 1.7% to 3.1% and from 3.6% to 5.6%, respectively. This annual survey examined 45,000 school age students nationwide
    • Zickler P: Annual Survey Finds Increasing Teen use of Ecstasy, Steroids, 2001. This survey of school age students found that from 1999 to 2000, Ecstasy use increased in eighth-graders and 12th-graders from 1.7% to 3.1% and from 3.6% to 5.6%, respectively. This annual survey examined 45,000 school age students nationwide.
    • Annual Survey Finds Increasing Teen Use of Ecstasy, Steroids, 2001
    • Zickler, P.1
  • 2
    • 0022839628 scopus 로고
    • The background and chemistry of MDMA
    • PID: 2880943, COI: 1:CAS:528:DyaL2sXhtlWjt7c%3D
    • Shulgin A: The background and chemistry of MDMA. J Psychoactive Drugs 1986, 18:291–304.
    • (1986) J Psychoactive Drugs , vol.18 , pp. 291-304
    • Shulgin, A.1
  • 3
    • 0022148262 scopus 로고
    • Information on Ecstasy
    • PID: 2865906, COI: 1:STN:280:DyaL28%2FkvVarug%3D%3D
    • Greer G, Strassman R: Information on Ecstasy. Am J Psychiatry 1985, 142:1391.
    • (1985) Am J Psychiatry , vol.142 , pp. 1391
    • Greer, G.1    Strassman, R.2
  • 4
    • 0022838801 scopus 로고
    • Subjective reports of the effects of MDMA in a clinical setting
    • PID: 2880946, COI: 1:STN:280:DyaL2s7ktVGgtg%3D%3D
    • Greer G, Tolbert R: Subjective reports of the effects of MDMA in a clinical setting. J Psychoactive Drugs 1986, 18:319–327.
    • (1986) J Psychoactive Drugs , vol.18 , pp. 319-327
    • Greer, G.1    Tolbert, R.2
  • 5
    • 0022838197 scopus 로고
    • Differences between the mechanism of action of MDMA, MBDB, and the classic hallucinogens. Identification of a new therapeutic class: entactogens
    • PID: 2880944, COI: 1:CAS:528:DyaL2sXhtlWjtL4%3D
    • Nichols D: Differences between the mechanism of action of MDMA, MBDB, and the classic hallucinogens. Identification of a new therapeutic class: entactogens. J Psychoactive Drugs 1986, 18:305–313.
    • (1986) J Psychoactive Drugs , vol.18 , pp. 305-313
    • Nichols, D.1
  • 6
    • 0022357597 scopus 로고
    • Hallucinogenic amphetamine selectively destroys brain serotonin nerve terminals
    • PID: 4023719, COI: 1:CAS:528:DyaL2MXltlGjtbw%3D
    • Ricaurte G, Bryan G, Strauss L, et al.: Hallucinogenic amphetamine selectively destroys brain serotonin nerve terminals. Science 1985, 229:986–988. DOI: 10.1126/science.4023719
    • (1985) Science , vol.229 , pp. 986-988
    • Ricaurte, G.1    Bryan, G.2    Strauss, L.3
  • 7
    • 0023991821 scopus 로고
    • Ecstasy returns to schedule I
    • PID: 2895498, COI: 1:STN:280:DyaL1c7nvVSltQ%3D%3D
    • Barnes D: Ecstasy returns to schedule I. Science 1988, 240:24. DOI: 10.1126/science.2895498
    • (1988) Science , vol.240 , pp. 24
    • Barnes, D.1
  • 8
    • 0026644079 scopus 로고
    • Ecstasy-fueled "rave" parties become dances of death for English youths
    • COI: 1:STN:280:DyaK38zovFertg%3D%3D
    • Randall T: Ecstasy-fueled "rave" parties become dances of death for English youths. Med News Perspect 1992, 268:1505–1506.
    • (1992) Med News Perspect , vol.268 , pp. 1505-1506
    • Randall, T.1
  • 9
    • 21344488813 scopus 로고
    • The new psychedelic culture: LSD, Ecstasy, "rave" parties and The Grateful Dead
    • Millman R, Beeder B: The new psychedelic culture: LSD, Ecstasy, "rave" parties and The Grateful Dead. Psychiatr Ann 1994, 24:148–150.
    • (1994) Psychiatr Ann , vol.24 , pp. 148-150
    • Millman, R.1    Beeder, B.2
  • 10
    • 0034720722 scopus 로고    scopus 로고
    • Raves: a review of the culture, the drugs and the prevention of harm
    • PID: 10906922, COI: 1:STN:280:DC%2BD3czmsVahug%3D%3D
    • Weir E: Raves: a review of the culture, the drugs and the prevention of harm. CMAJ 2000, 162:1843–1848.
    • (2000) CMAJ , vol.162 , pp. 1843-1848
    • Weir, E.1
  • 11
    • 0026639917 scopus 로고
    • "Rave" scene, Ecstasy use, leap Atlantic
    • PID: 1355568, COI: 1:STN:280:DyaK38zovFertw%3D%3D
    • Randall T: "Rave" scene, Ecstasy use, leap Atlantic. JAMA 1992, 268:1506. DOI: 10.1001/jama.268.12.1506
    • (1992) JAMA , vol.268 , pp. 1506
    • Randall, T.1
  • 12
    • 0023616493 scopus 로고
    • Incidence of recreational use of 3,4-methylenedimethoxymethamphetamine (MDMA, "Ecstasy") on an undergraduate campus
    • PID: 2891034, COI: 1:STN:280:DyaL1c%2FmsFOlsg%3D%3D
    • Peroutka S: Incidence of recreational use of 3,4-methylenedimethoxymethamphetamine (MDMA, "Ecstasy") on an undergraduate campus. N Engl J Med 1987, 317:1542–1543.
    • (1987) N Engl J Med , vol.317 , pp. 1542-1543
    • Peroutka, S.1
  • 13
    • 0034925477 scopus 로고    scopus 로고
    • Patterns of recreational drug use at dance events in Edinburgh, Scotland
    • PID: 11440614, COI: 1:STN:280:DC%2BD3Mzos1Kltg%3D%3D
    • Riley S, James C, Gregory D, et al.: Patterns of recreational drug use at dance events in Edinburgh, Scotland. Addiction 2001, 96:1035–1047. DOI: 10.1046/j.1360-0443.2001.967103513.x
    • (2001) Addiction , vol.96 , pp. 1035-1047
    • Riley, S.1    James, C.2    Gregory, D.3
  • 14
    • 12644312087 scopus 로고
    • MDMA (Ecstasy): an old drug with new tricks
    • Schuckit M: MDMA (Ecstasy): an old drug with new tricks. Drug Abuse Alcohol Newsletter 1994, 23:1–4.
    • (1994) Drug Abuse Alcohol Newsletter , vol.23 , pp. 1-4
    • Schuckit, M.1
  • 15
    • 0033778086 scopus 로고    scopus 로고
    • Ecstasy (MDMA): a review of its possible persistent psychological effects
    • PID: 11105933, COI: 1:CAS:528:DC%2BD3cXosVKrsrY%3D
    • Morgan M: Ecstasy (MDMA): a review of its possible persistent psychological effects. Psychopharmacology 2000, 152:230–248. DOI: 10.1007/s002130000545
    • (2000) Psychopharmacology , vol.152 , pp. 230-248
    • Morgan, M.1
  • 16
    • 0029846521 scopus 로고    scopus 로고
    • Analysis of 3, 4-methylenedioxymethamphetamine (MDMA) and its metabolites in plasma and urine by HPLC-DAD and GC-MS
    • PID: 8889680, COI: 1:CAS:528:DyaK28XlvF2rtb4%3D
    • Helmlin H-J, Bracher K, Bourquin D, et al.: Analysis of 3, 4-methylenedioxymethamphetamine (MDMA) and its metabolites in plasma and urine by HPLC-DAD and GC-MS. J Anal Toxicol 1996, 20:432–440.
    • (1996) J Anal Toxicol , vol.20 , pp. 432-440
    • Helmlin, H.-J.1    Bracher, K.2    Bourquin, D.3
  • 17
    • 0035013766 scopus 로고    scopus 로고
    • Profiles of urine samples taken from Ecstasy users at rave parties: analysis by immunoassays, HPLC, and GC-MS
    • PID: 11386639, COI: 1:CAS:528:DC%2BD3MXjvFart7w%3D
    • Zhao H, Brenneisen R, Scholer A, et al.: Profiles of urine samples taken from Ecstasy users at rave parties: analysis by immunoassays, HPLC, and GC-MS. J Anal Toxicol 2001, 25:258–269.
    • (2001) J Anal Toxicol , vol.25 , pp. 258-269
    • Zhao, H.1    Brenneisen, R.2    Scholer, A.3
  • 18
    • 0035097852 scopus 로고    scopus 로고
    • Sweat testing of MDMA with the Drugwipe Analytical Device: a controlled study with two volunteers
    • PID: 11300507, COI: 1:CAS:528:DC%2BD3MXitFajtL0%3D, MDMA and its metabolites are not easily detected human bodily fluids. this study, immunochemical strips applied to two human subjects between 2 and 12 hours after initial ingestion of MDMA were able to detect MDMA its metabolites their sweat, suggesting that the immunochemical strips may be an effective means of rapidly detecting this substance humans suspected of ingesting MDMA
    • Pacifici R, Farre M, Pichini S, et al.: Sweat testing of MDMA with the Drugwipe Analytical Device: a controlled study with two volunteers. J Anal Toxicol 2001, 25:144–146. MDMA and its metabolites are not easily detected in human bodily fluids. In this study, immunochemical strips applied to two human subjects between 2 and 12 hours after initial ingestion of MDMA were able to detect MDMA in its metabolites in their sweat, suggesting that the immunochemical strips may be an effective means of rapidly detecting this substance in humans suspected of ingesting MDMA.
    • (2001) J Anal Toxicol , vol.25 , pp. 144-146
    • Pacifici, R.1    Farre, M.2    Pichini, S.3
  • 19
    • 0023272774 scopus 로고
    • 3,4-methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine destroy serotonin terminals in rat brain: quantification of neurodegeneration by measurement of [3H]paroxetinelabeled serotonin uptake sites
    • PID: 2443644, COI: 1:CAS:528:DyaL2sXmt12jsr0%3D
    • Battaglia G, Yeh S, O’Hearn E, et al.: 3,4-methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine destroy serotonin terminals in rat brain: quantification of neurodegeneration by measurement of [3H]paroxetinelabeled serotonin uptake sites. J Pharmacol Exp Ther 1987, 242:911–916.
    • (1987) J Pharmacol Exp Ther , vol.242 , pp. 911-916
    • Battaglia, G.1    Yeh, S.2    O’Hearn, E.3
  • 20
    • 0023735752 scopus 로고
    • Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) cause selective ablation of serotonergic axon terminals in forebrain: immunocytochemical evidence for neurotoxicity
    • PID: 2457659, COI: 1:CAS:528:DyaL1cXlsVantLc%3D
    • O’Hearn E, Battaglia G, De Souza E, et al.: Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) cause selective ablation of serotonergic axon terminals in forebrain: immunocytochemical evidence for neurotoxicity. J Neurosci 1988, 8:2788–2803.
    • (1988) J Neurosci , vol.8 , pp. 2788-2803
    • O’Hearn, E.1    Battaglia, G.2    De Souza, E.3
  • 21
    • 0023811368 scopus 로고
    • Neurochemical and neurohistiological slterations in the rat and monkey produced by orally administered methylenedioxymethamphetamine (MDMA)
    • PID: 2456631, COI: 1:CAS:528:DyaL1cXltVClu70%3D
    • Slikker W Jr, Ali S, Scallet A, et al.: Neurochemical and neurohistiological slterations in the rat and monkey produced by orally administered methylenedioxymethamphetamine (MDMA). Toxicol Appl Pharmacol 1988, 94:448–457. DOI: 10.1016/0041-008X(88)90285-2
    • (1988) Toxicol Appl Pharmacol , vol.94 , pp. 448-457
    • Slikker, W.1    Ali, S.2    Scallet, A.3
  • 22
    • 0028176910 scopus 로고
    • Serotonin neurotoxicity after (+/-) 3,4-methylenedioxymethamphetamine (MDMA; "Ecstasy"): a controlled study in humans
    • PID: 7517677, COI: 1:CAS:528:DyaK2cXkslGnur4%3D
    • McCann U, Ridenour A, Shaham Y, Ricaurte G: Serotonin neurotoxicity after (+/-) 3,4-methylenedioxymethamphetamine (MDMA; "Ecstasy"): a controlled study in humans. Neuropsychopharmacology 1994, 10:129–138.
    • (1994) Neuropsychopharmacology , vol.10 , pp. 129-138
    • McCann, U.1    Ridenour, A.2    Shaham, Y.3    Ricaurte, G.4
  • 23
    • 0032585201 scopus 로고    scopus 로고
    • Positron emission tomographic evidence of toxic effect of MDMA ("Ecstasy") on brain serotonin neurons in human beings
    • PID: 9807990, COI: 1:CAS:528:DyaK1cXnsVSmsLk%3D
    • McCann U, Szabo Z, Scheffel U, et al.: Positron emission tomographic evidence of toxic effect of MDMA ("Ecstasy") on brain serotonin neurons in human beings. Lancet 1998, 352:1433–1437. DOI: 10.1016/S0140-6736(98)04329-3
    • (1998) Lancet , vol.352 , pp. 1433-1437
    • McCann, U.1    Szabo, Z.2    Scheffel, U.3
  • 24
    • 0022911033 scopus 로고
    • The effects of 3,4-methylenedioxymethamphetamine (MDMA) and 3, 4-methylenedioxyamphetamine (MDA) on monoaminergic systems in the rat brain
    • PID: 2875893, COI: 1:CAS:528:DyaL28XlvVektbg%3D
    • Stone D, Stahl D, Hanson G, Gibb J: The effects of 3,4-methylenedioxymethamphetamine (MDMA) and 3, 4-methylenedioxyamphetamine (MDA) on monoaminergic systems in the rat brain. Eur J Pharmacol 1986, 128:41–48. DOI: 10.1016/0014-2999(86)90555-8
    • (1986) Eur J Pharmacol , vol.128 , pp. 41-48
    • Stone, D.1    Stahl, D.2    Hanson, G.3    Gibb, J.4
  • 25
    • 0022580189 scopus 로고
    • 3,4-methylenedioxymethamphetamine (MDMA): stereoselective interactions at brain 5-HT1 and 5-HT2 receptors
    • PID: 2871581, COI: 1:CAS:528:DyaL28XltVygs70%3D
    • Lyon R, Glennon R, Titeler M: 3,4-methylenedioxymethamphetamine (MDMA): stereoselective interactions at brain 5-HT1 and 5-HT2 receptors. Psychopharmacology 1986, 88:525–526. DOI: 10.1007/BF00178519
    • (1986) Psychopharmacology , vol.88 , pp. 525-526
    • Lyon, R.1    Glennon, R.2    Titeler, M.3
  • 26
    • 0023228746 scopus 로고
    • Stereochemical effects of 3,4-methylenedioxymethamphetamine (MDMA) and related amphetamine derivatives on inhibition of uptake of [3H]monoamines into synaptosomes from different regions of rat brain
    • PID: 2886126, COI: 1:CAS:528:DyaL2sXlsVOitLs%3D
    • Steele T, Nichols D, Yim G: Stereochemical effects of 3,4-methylenedioxymethamphetamine (MDMA) and related amphetamine derivatives on inhibition of uptake of [3H]monoamines into synaptosomes from different regions of rat brain. Biochem Pharmacol 1987, 36:2297–2303. DOI: 10.1016/0006-2952(87)90594-6
    • (1987) Biochem Pharmacol , vol.36 , pp. 2297-2303
    • Steele, T.1    Nichols, D.2    Yim, G.3
  • 27
    • 0023475168 scopus 로고
    • Depression of rat brain tryptophan hydroxylase activity following the acute administration of methylenedioxymethamphetamine
    • PID: 2891359, COI: 1:CAS:528:DyaL1cXjtFymtA%3D%3D
    • Schmidt C, Taylor V: Depression of rat brain tryptophan hydroxylase activity following the acute administration of methylenedioxymethamphetamine. Biochem Pharmacol 1987, 36:4095–4102. DOI: 10.1016/0006-2952(87)90566-1
    • (1987) Biochem Pharmacol , vol.36 , pp. 4095-4102
    • Schmidt, C.1    Taylor, V.2
  • 28
    • 0023484528 scopus 로고
    • Immediate and longterm effects of 3,4-methylenedioxymethamphetamine on serotonin pathways in brain of rat
    • PID: 2893986, COI: 1:CAS:528:DyaL1cXkvFaiuw%3D%3D
    • Stone D, Merchant K, Hanson G, Gibb J: Immediate and longterm effects of 3,4-methylenedioxymethamphetamine on serotonin pathways in brain of rat. Neuropharmacology 1987, 26:1677–1683. DOI: 10.1016/0028-3908(87)90117-1
    • (1987) Neuropharmacology , vol.26 , pp. 1677-1683
    • Stone, D.1    Merchant, K.2    Hanson, G.3    Gibb, J.4
  • 30
    • 0030971740 scopus 로고    scopus 로고
    • Ecstasy (MDMA) in recreational users: self-report psychological and physiological effects
    • Davidson D, Parrott A: Ecstasy (MDMA) in recreational users: self-report psychological and physiological effects. Hum Psychopharmacol 1997, 12:221–226. DOI: 10.1002/(SICI)1099-1077(199705/06)12:3<221::AID-HUP854>3.0.CO;2-C
    • (1997) Hum Psychopharmacol , vol.12 , pp. 221-226
    • Davidson, D.1    Parrott, A.2
  • 31
    • 0026716102 scopus 로고
    • Phenomenology and sequelae of 3,4-methylenedioxymethampethamine use
    • PID: 1350613, COI: 1:STN:280:DyaK383nslSluw%3D%3D
    • Liester M, Grob C, Bravo G, Walsh R: Phenomenology and sequelae of 3,4-methylenedioxymethampethamine use. J Nerv Ment Dis 1992, 180:345–352. DOI: 10.1097/00005053-199206000-00001
    • (1992) J Nerv Ment Dis , vol.180 , pp. 345-352
    • Liester, M.1    Grob, C.2    Bravo, G.3    Walsh, R.4
  • 32
    • 0022834268 scopus 로고
    • MDMA: nonmedical use and intoxication
    • PID: 2880950, COI: 1:STN:280:DyaL2s7ktVGgug%3D%3D
    • Siegel R: MDMA: nonmedical use and intoxication. J Psychoactive Drugs 1986, 18:349–354.
    • (1986) J Psychoactive Drugs , vol.18 , pp. 349-354
    • Siegel, R.1
  • 33
    • 0026710950 scopus 로고
    • Recreational MDMA use in Sydney: a profile of ‘Ecstasy’ users and their experiences with the drug
    • COI: 1:STN:280:DyaK38znvFCiug%3D%3D
    • Solowij N, Hall W, Lee N: Recreational MDMA use in Sydney: a profile of ‘Ecstasy’ users and their experiences with the drug. Br J Psychiatry 1992, 87:1161–1172.
    • (1992) Br J Psychiatry , vol.87 , pp. 1161-1172
    • Solowij, N.1    Hall, W.2    Lee, N.3
  • 34
    • 85047691384 scopus 로고
    • "Eve" and "Ecstasy": a report of five deaths associated with the use of MDA and MDMA
    • PID: 2881002, COI: 1:STN:280:DyaL2s7ktFGntg%3D%3D
    • Dowling G, McDouough E, Bost R: "Eve" and "Ecstasy": a report of five deaths associated with the use of MDA and MDMA. JAMA 1987, 257:1615–1617. DOI: 10.1001/jama.257.12.1615
    • (1987) JAMA , vol.257 , pp. 1615-1617
    • Dowling, G.1    McDouough, E.2    Bost, R.3
  • 35
    • 0018603617 scopus 로고
    • 3,4-methylenedioxyamphetamine overdose
    • PID: 540488, COI: 1:STN:280:DyaL3c7lsF2gsA%3D%3D
    • Lukaszewski T: 3,4-methylenedioxyamphetamine overdose. Clin Toxicol 1979, 15:405–409.
    • (1979) Clin Toxicol , vol.15 , pp. 405-409
    • Lukaszewski, T.1
  • 36
    • 0018741571 scopus 로고
    • Fatal intoxication from 3,4-methylenedioxyamphetamine
    • PID: 512617, COI: 1:CAS:528:DyaE1MXhs1aktb8%3D
    • Poklis A, Mackell M, Drake W: Fatal intoxication from 3,4-methylenedioxyamphetamine. J Forensic Sci 1979, 24:70–75.
    • (1979) J Forensic Sci , vol.24 , pp. 70-75
    • Poklis, A.1    Mackell, M.2    Drake, W.3
  • 37
    • 0015267291 scopus 로고
    • A fatal case involving methylenedioxyamphetamine
    • PID: 5043280, COI: 1:STN:280:DyaE383jtlWgtA%3D%3D
    • Reed D, Cravey R, Sedgwick P: A fatal case involving methylenedioxyamphetamine. Clin Toxicol 1972, 5:3–6.
    • (1972) Clin Toxicol , vol.5 , pp. 3-6
    • Reed, D.1    Cravey, R.2    Sedgwick, P.3
  • 38
    • 0026465821 scopus 로고
    • Another death from Ecstasy
    • PID: 1347789, COI: 1:STN:280:DyaK387psVamsg%3D%3D
    • Campkin N, Davies U: Another death from Ecstasy. J R Soc Med 1992, 85:61.
    • (1992) J R Soc Med , vol.85 , pp. 61
    • Campkin, N.1    Davies, U.2
  • 39
    • 0030032101 scopus 로고    scopus 로고
    • A fatal trip with Ecstasy: a case of 3,4-methylenedioxymethamphetamine/ 3,4-methylenedioxyamphetamine toxicity
    • Coore J: A fatal trip with Ecstasy: a case of 3,4-methylenedioxymethamphetamine/ 3,4-methylenedioxyamphetamine toxicity. J R Soc Med 1996, 89:51–52.
    • (1996) J R Soc Med , vol.89 , pp. 51-52
    • Coore, J.1
  • 40
    • 0027379141 scopus 로고
    • Hyponatraemia and catatonic stupor after taking Ecstasy
    • PID: 7903884, COI: 1:STN:280:DyaK2c7gtVOhtg%3D%3D
    • Maxwell D, Polkey M, Henry J: Hyponatraemia and catatonic stupor after taking Ecstasy. BMJ 1993, 307:1399.
    • (1993) BMJ , vol.307 , pp. 1399
    • Maxwell, D.1    Polkey, M.2    Henry, J.3
  • 41
    • 0025730305 scopus 로고
    • Ecstasy, 3,4-methylenedioxymethamphetamine (MDMA), a fatality associated with coagulopathy and hyperthermia
    • COI: 1:STN:280:DyaK3M3oslSktQ%3D%3D
    • Chadwick I, Linsley A, Freemont A, et al.: Ecstasy, 3,4-methylenedioxymethamphetamine (MDMA), a fatality associated with coagulopathy and hyperthermia. J Royal Soc Med 1991, 84:371.
    • (1991) J Royal Soc Med , vol.84 , pp. 371
    • Chadwick, I.1    Linsley, A.2    Freemont, A.3
  • 42
    • 0029037426 scopus 로고
    • Ecstasy induced hepatitis mimicking viral hepatitis
    • PID: 7615289, COI: 1:STN:280:DyaK2MzktVajsw%3D%3D
    • Dykhuizen R, Brunt P, Atkinson P, et al.: Ecstasy induced hepatitis mimicking viral hepatitis. Gut 1995, 36:939–941.
    • (1995) Gut , vol.36 , pp. 939-941
    • Dykhuizen, R.1    Brunt, P.2    Atkinson, P.3
  • 43
    • 0030272961 scopus 로고    scopus 로고
    • Chronic Ecstasy (3,4-methylenedioxymethamphetamine) abuse: a recurrent and unpredictable cause of severe acute hepatitis
    • PID: 8912157, COI: 1:STN:280:DyaK2s%2FmvV2luw%3D%3D
    • Fidler H, Dhillon A, Gertner D, Burroughs A: Chronic Ecstasy (3,4-methylenedioxymethamphetamine) abuse: a recurrent and unpredictable cause of severe acute hepatitis. J Hepatol 1996, 25:563–566. DOI: 10.1016/S0168-8278(96)80217-0
    • (1996) J Hepatol , vol.25 , pp. 563-566
    • Fidler, H.1    Dhillon, A.2    Gertner, D.3    Burroughs, A.4
  • 44
    • 0028952031 scopus 로고
    • Hepatotoxicity and accelerated fibrosis following 3,4-methylenedioxymethamphetamine (Ecstasy) usage
    • PID: 7797836, COI: 1:STN:280:DyaK2MzhvVCntA%3D%3D
    • Khakoo S, Coles C, Armstrong J, Barry R: Hepatotoxicity and accelerated fibrosis following 3,4-methylenedioxymethamphetamine (Ecstasy) usage. J Clin Gastroenterol 1995, 20:244–247. DOI: 10.1097/00004836-199504000-00017
    • (1995) J Clin Gastroenterol , vol.20 , pp. 244-247
    • Khakoo, S.1    Coles, C.2    Armstrong, J.3    Barry, R.4
  • 45
    • 0027186221 scopus 로고
    • Subarachnoid hemorrhage associated with MDMA abuse
    • PID: 8105032, COI: 1:STN:280:DyaK2c%2FhsFWisQ%3D%3D
    • Gledhill J, Moore D, Bell D, Henry J: Subarachnoid hemorrhage associated with MDMA abuse. J Neurol Neurosurg Psychiatry 1993, 56:1036–1037.
    • (1993) J Neurol Neurosurg Psychiatry , vol.56 , pp. 1036-1037
    • Gledhill, J.1    Moore, D.2    Bell, D.3    Henry, J.4
  • 46
    • 0029004267 scopus 로고
    • Cerebral infarction associated with 3,4-methylenedioxymethamphetamine (Ecstasy) abuse
    • PID: 7628499, COI: 1:STN:280:DyaK2MzlsVOiug%3D%3D
    • Hanyu A, Ikeguchi K, Imai H, et al.: Cerebral infarction associated with 3,4-methylenedioxymethamphetamine (Ecstasy) abuse. Eur Neurol 1995, 35:173.
    • (1995) Eur Neurol , vol.35 , pp. 173
    • Hanyu, A.1    Ikeguchi, K.2    Imai, H.3
  • 47
    • 0033843851 scopus 로고    scopus 로고
    • Aortic dissection after ingestion of Ecstasy MDMA
    • PID: 10990289, COI: 1:STN:280:DC%2BD3cvkt1egug%3D%3D
    • Duflou J, Mark A: Aortic dissection after ingestion of Ecstasy MDMA. Am J Forensic Med Pathol 2000, 21:261–263. DOI: 10.1097/00000433-200009000-00016
    • (2000) Am J Forensic Med Pathol , vol.21 , pp. 261-263
    • Duflou, J.1    Mark, A.2
  • 48
    • 0024230815 scopus 로고
    • Ecstasy and sudden cardiac death
    • PID: 3239555, COI: 1:STN:280:DyaL1M7ptVGqtw%3D%3D
    • Suarez R, Riemersma R: Ecstasy and sudden cardiac death. Am J Forensic Med Pathol 1988, 9:339–341.
    • (1988) Am J Forensic Med Pathol , vol.9 , pp. 339-341
    • Suarez, R.1    Riemersma, R.2
  • 49
    • 0024375279 scopus 로고
    • Serotonergic studies in patients with affective and personality disorders
    • PID: 2735812, COI: 1:CAS:528:DyaK3MXksVOitLo%3D
    • Coccaro E, Siever L, Klar H, et al.: Serotonergic studies in patients with affective and personality disorders. Arch Gen Psychiatry 1989, 46:587–599.
    • (1989) Arch Gen Psychiatry , vol.46 , pp. 587-599
    • Coccaro, E.1    Siever, L.2    Klar, H.3
  • 50
    • 0025748875 scopus 로고
    • Psychiatric illness associated with Ecstasy
    • PID: 1683934, COI: 1:STN:280:DyaK38%2FnvFKjsw%3D%3D
    • Benazzi F, Mazzoli M: Psychiatric illness associated with Ecstasy. Lancet 1991, 338:1520. DOI: 10.1016/0140-6736(91)92332-V
    • (1991) Lancet , vol.338 , pp. 1520
    • Benazzi, F.1    Mazzoli, M.2
  • 51
    • 0030741356 scopus 로고    scopus 로고
    • Mood and cognitive effects of +/− 3,4-methylenedioxymethamphetamine (MDMA; Ecstasy): weekend-end "high" followed by mid-week low
    • PID: 9293041, COI: 1:STN:280:DyaK2svjvVGmsQ%3D%3D
    • Curran H, Travill R: Mood and cognitive effects of +/− 3,4-methylenedioxymethamphetamine (MDMA; Ecstasy): weekend-end "high" followed by mid-week low. Addiction 1997, 92:821–831. DOI: 10.1111/j.1360-0443.1997.tb02951.x
    • (1997) Addiction , vol.92 , pp. 821-831
    • Curran, H.1    Travill, R.2
  • 52
    • 0026707316 scopus 로고
    • Chronic 3,4-methylenedioxymethamphetamine (MDMA) use: effects on mood and neuropsychological function
    • PID: 1357957, COI: 1:STN:280:DyaK3s%2FjsFWltQ%3D%3D
    • Krystal J: Chronic 3,4-methylenedioxymethamphetamine (MDMA) use: effects on mood and neuropsychological function? Am J Drug Alcohol Abuse 1992, 18:331–341.
    • (1992) Am J Drug Alcohol Abuse , vol.18 , pp. 331-341
    • Krystal, J.1
  • 53
    • 0025863667 scopus 로고
    • Lasting neuropsychiatric sequelae of (+/-) methylenedioxymethamphetamine (Ecstasy) in recreational use
    • PID: 1684975, COI: 1:STN:280:DyaK387htlWjsQ%3D%3D
    • McCann U, Ricaurte G: Lasting neuropsychiatric sequelae of (+/-) methylenedioxymethamphetamine (Ecstasy) in recreational use. J Clin Psychopharmacol 1991, 11:302–305. DOI: 10.1097/00004714-199110000-00005
    • (1991) J Clin Psychopharmacol , vol.11 , pp. 302-305
    • McCann, U.1    Ricaurte, G.2
  • 54
    • 0028106251 scopus 로고
    • Diversity of psychopathology associated with use of 3,4-methylenedioxymethamphetamine (Ecstasy)
    • PID: 7994514, COI: 1:STN:280:DyaK2M%2Fos1OksA%3D%3D
    • McGuire P, Cope H, Fahy T: Diversity of psychopathology associated with use of 3,4-methylenedioxymethamphetamine (Ecstasy). Br J Psychiatry 1994, 165:391–395.
    • (1994) Br J Psychiatry , vol.165 , pp. 391-395
    • McGuire, P.1    Cope, H.2    Fahy, T.3
  • 55
    • 0031677797 scopus 로고    scopus 로고
    • Ecstasy (MDMA) effects on mood and cognition: before, during and after a Saturday night dance
    • PID: 9784083, COI: 1:CAS:528:DyaK1cXmtlygsLs%3D
    • Parrott A, Lasky J: Ecstasy (MDMA) effects on mood and cognition: before, during and after a Saturday night dance. Psychopharmacology 1998, 139:261–268. DOI: 10.1007/s002130050714
    • (1998) Psychopharmacology , vol.139 , pp. 261-268
    • Parrott, A.1    Lasky, J.2
  • 56
    • 0032168235 scopus 로고    scopus 로고
    • MDMA (Ecstasy) consumption in the context of polydrug use: a report on 150 patients
    • PID: 9788011, COI: 1:CAS:528:DyaK1cXkslyktr0%3D
    • Schifano F, Di Furia L, Minicuci N, Briolo R: MDMA (Ecstasy) consumption in the context of polydrug use: a report on 150 patients. Drug Alcohol Depend 1998, 52:85–90. DOI: 10.1016/S0376-8716(98)00051-9
    • (1998) Drug Alcohol Depend , vol.52 , pp. 85-90
    • Schifano, F.1    Di Furia, L.2    Minicuci, N.3    Briolo, R.4
  • 57
    • 0027943773 scopus 로고
    • Psychiatric sequelae of MDMA (Ecstasy) and related drugs
    • Cassidy G, Ballard C: Psychiatric sequelae of MDMA (Ecstasy) and related drugs. Ir J Psychol Med 1994, 11:132–133.
    • (1994) Ir J Psychol Med , vol.11 , pp. 132-133
    • Cassidy, G.1    Ballard, C.2
  • 58
    • 0025950643 scopus 로고
    • Hyde C: Ecstasy psychosis and flashbacks
    • PID: 1684523, COI: 1:STN:280:DyaK38%2Fps1Oquw%3D%3D
    • Creighton F, Black D, Hyde C: Ecstasy psychosis and flashbacks. Br J Psychiatry 1991, 159:713–715.
    • (1991) Br J Psychiatry , vol.159 , pp. 713-715
    • Creighton, F.1    Black, D.2
  • 59
    • 0026073632 scopus 로고
    • Chronic paranoid psychosis after misuse of MDMA (Ecstasy)
    • PID: 1673631, COI: 1:STN:280:DyaK3M3hsFeisg%3D%3D
    • McGuire P, Fahy T: Chronic paranoid psychosis after misuse of MDMA (Ecstasy). BMJ 1991, 302:697.
    • (1991) BMJ , vol.302 , pp. 697
    • McGuire, P.1    Fahy, T.2
  • 60
    • 0025936650 scopus 로고
    • Chronic atypical psychosis associated with MDMA (Ecstasy) abuse
    • PID: 1682711, COI: 1:STN:280:DyaK38%2Fksl2quw%3D%3D
    • Schifano F: Chronic atypical psychosis associated with MDMA (Ecstasy) abuse. Lancet 1991, 338:1335. DOI: 10.1016/0140-6736(91)92633-D
    • (1991) Lancet , vol.338 , pp. 1335
    • Schifano, F.1
  • 61
    • 0035055807 scopus 로고    scopus 로고
    • An "accidental" acute psychosis with Ecstasy use
    • PID: 11333007, COI: 1:STN:280:DC%2BD3MrgsFagtA%3D%3D, This case study presented one individual who experienced an acute episode of psychosis characterized by delusions and violent behavior 12 hours after ingesting MDMA. Although he had no previously known psychiatric history, he met criteria for mild major depression with some psychotic symptoms 6 months after taking MDMA
    • Vaiva G, Boss V, Bailly D, et al.: An "accidental" acute psychosis with Ecstasy use. J Psychoactive Drugs 2001, 33:95–98. This case study presented one individual who experienced an acute episode of psychosis characterized by delusions and violent behavior 12 hours after ingesting MDMA. Although he had no previously known psychiatric history, he met criteria for mild major depression with some psychotic symptoms 6 months after taking MDMA.
    • (2001) J Psychoactive Drugs , vol.33 , pp. 95-98
    • Vaiva, G.1    Boss, V.2    Bailly, D.3
  • 62
    • 0343619414 scopus 로고    scopus 로고
    • Psychobiological problems in heavy ‘Ecstasy’ (MDMA) polydrug users
    • PID: 10821995, COI: 1:STN:280:DC%2BD3czpsVyqsw%3D%3D, this study using clinical symptoms self-assessment scales to compare a group of heavy MDMA users with a non-MDMA using control group, heavy users had significantly greater levels of anxiety, paranoid ideation, anorexia, somatization, obsessionality, psychoticism, and disturbed sleep patterns than did controls. Light MDMA users had intermediate symptom on the majority of self-assessment scores when compared with controls except on measures of paranoid ideation and psychoticism. The authors suggest those early indicators (psychoticism and paranoia) of developing psychiatric disorders present light users may continue with continued MDMA use
    • Parrott A, Sisk E, Turner J: Psychobiological problems in heavy ‘Ecstasy’ (MDMA) polydrug users. Drug Alcohol Depend 2000, 60:105–110. In this study using clinical symptoms self-assessment scales to compare a group of heavy MDMA users with a non-MDMA using control group, heavy users had significantly greater levels of anxiety, paranoid ideation, anorexia, somatization, obsessionality, psychoticism, and disturbed sleep patterns than did controls. Light MDMA users had intermediate symptom on the majority of self-assessment scores when compared with controls except on measures of paranoid ideation and psychoticism. The authors suggest those early indicators (psychoticism and paranoia) of developing psychiatric disorders present in light users may continue with continued MDMA use. DOI: 10.1016/S0376-8716(99)00146-5
    • (2000) Drug Alcohol Depend , vol.60 , pp. 105-110
    • Parrott, A.1    Sisk, E.2    Turner, J.3
  • 63
    • 0026674432 scopus 로고
    • MDMA (Ecstasy) precipitation of panic disorder
    • PID: 1356491, COI: 1:STN:280:DyaK3s%2Fgtlymtg%3D%3D
    • Pallanti S, Mazzi D: MDMA (Ecstasy) precipitation of panic disorder. Biol Psychiatry 1992, 32:91–95. DOI: 10.1016/0006-3223(92)90145-P
    • (1992) Biol Psychiatry , vol.32 , pp. 91-95
    • Pallanti, S.1    Mazzi, D.2
  • 64
    • 0342374686 scopus 로고
    • Ecstasy (MDMA)-induced panic
    • PID: 2563207, COI: 1:STN:280:DyaL1M7gtlKnsw%3D%3D
    • Whitaker-Azmitia P, Aronson T: Ecstasy (MDMA)-induced panic. Am J Psychiatry 1989, 146:119.
    • (1989) Am J Psychiatry , vol.146 , pp. 119
    • Whitaker-Azmitia, P.1    Aronson, T.2
  • 65
    • 0031753399 scopus 로고    scopus 로고
    • Recreational use of Ecstasy (MDMA) is associated with elevated impulsivity
    • PID: 9718589, COI: 1:CAS:528:DyaK1cXlslWktbo%3D, A group of 16 MDMA users was compared with 1) a group of 12 non-MDMA users with substance use and personal histories comparable to the MDMA users, and 2) a group of 16 non-substance-using controls. Using the Impulsiveness, Venturesomeness, and Empathy Scale (IVE), a significant difference between the MDMA group and the other groups was seen on measures of impulsiveness but no significant differences were reported on other scale measures
    • Morgan M: Recreational use of Ecstasy (MDMA) is associated with elevated impulsivity. Neuropsychopharmacology 1998, 19:252–264. A group of 16 MDMA users was compared with 1) a group of 12 non-MDMA users with substance use and personal histories comparable to the MDMA users, and 2) a group of 16 non-substance-using controls. Using the Impulsiveness, Venturesomeness, and Empathy Scale (IVE), a significant difference between the MDMA group and the other groups was seen on measures of impulsiveness but no significant differences were reported on other scale measures. DOI: 10.1016/S0893-133X(98)00012-8
    • (1998) Neuropsychopharmacology , vol.19 , pp. 252-264
    • Morgan, M.1
  • 66
    • 0023255308 scopus 로고
    • Biochemical and histological evidence that methylenedioxymethamphetamine (MDMA) is toxic to neurons in the rat brain
    • PID: 2883295, COI: 1:CAS:528:DyaL2sXktFOksrY%3D
    • Commins D, Vosmer G, Virus R, et al.: Biochemical and histological evidence that methylenedioxymethamphetamine (MDMA) is toxic to neurons in the rat brain. J Pharmacol Exp Ther 1987, 241:338–345.
    • (1987) J Pharmacol Exp Ther , vol.241 , pp. 338-345
    • Commins, D.1    Vosmer, G.2    Virus, R.3
  • 67
    • 0023163857 scopus 로고
    • Neurotoxicity of the psychedelic amphetamine, methylenedioxymethamphetamine
    • PID: 2433425, COI: 1:CAS:528:DyaL2sXhtFentbg%3D
    • Schmidt C: Neurotoxicity of the psychedelic amphetamine, methylenedioxymethamphetamine. J Pharmacol Exp Ther 1987, 240:1–7.
    • (1987) J Pharmacol Exp Ther , vol.240 , pp. 1-7
    • Schmidt, C.1
  • 68
    • 0023819569 scopus 로고
    • (+/-) 3,4-methylenedioxymethamphetmine selectively damages central sertonergic neurons in nonhuman primates
    • PID: 2454332, COI: 1:CAS:528:DyaL1cXkvVKisbk%3D
    • Ricaurte G, Forno L, Wilson M, et al.: (+/-) 3,4-methylenedioxymethamphetmine selectively damages central sertonergic neurons in nonhuman primates. JAMA 1988, 260:51–55. DOI: 10.1001/jama.260.1.51
    • (1988) JAMA , vol.260 , pp. 51-55
    • Ricaurte, G.1    Forno, L.2    Wilson, M.3
  • 69
    • 0024383159 scopus 로고
    • 3,4-methylenedioxymethamphetamine (Ecstasy) selectively destroys brain serotonin terminals in Rhesus monkeys
    • PID: 2471824, COI: 1:CAS:528:DyaL1MXkslSrsLc%3D
    • Insel T, Battaglia G, Johannessen J, et al.: 3,4-methylenedioxymethamphetamine (Ecstasy) selectively destroys brain serotonin terminals in Rhesus monkeys. J Pharmacol Exp Ther 1989, 249:713–720.
    • (1989) J Pharmacol Exp Ther , vol.249 , pp. 713-720
    • Insel, T.1    Battaglia, G.2    Johannessen, J.3
  • 70
    • 0026612759 scopus 로고
    • Lasting effects of (+/-) 3,4-methylenedioxymethamphetamine (MDMA) on central serotonergic neurons in nonhuman primates: neurochemical observations
    • PID: 1374470, COI: 1:CAS:528:DyaK38XktVSktLc%3D
    • Ricaurte G, Martello A, Katz J, Martello M: Lasting effects of (+/-) 3,4-methylenedioxymethamphetamine (MDMA) on central serotonergic neurons in nonhuman primates: neurochemical observations. J Pharmacol Exp Ther 1992, 261:616–622.
    • (1992) J Pharmacol Exp Ther , vol.261 , pp. 616-622
    • Ricaurte, G.1    Martello, A.2    Katz, J.3    Martello, M.4
  • 71
    • 0023553581 scopus 로고
    • Monoamine metabolites in the cerebrospinal fluid of recreational users of 3,4-methylenedioxymethamphetamine
    • Peroutka S, Pascoe N, Faull K: Monoamine metabolites in the cerebrospinal fluid of recreational users of 3,4-methylenedioxymethamphetamine. Res Commun Substance Abuse 1987, 8:125–138.
    • (1987) Res Commun Substance Abuse , vol.8 , pp. 125-138
    • Peroutka, S.1    Pascoe, N.2    Faull, K.3
  • 72
    • 0025650065 scopus 로고
    • Aminergic metabolites in cerebrospinal fluid of humans previously exposed to MDMA: preliminary observations
    • PID: 1701292, COI: 1:CAS:528:DyaK3MXksVWktb4%3D
    • Ricaurte G, Finnegan K, Irwin I, Langston J: Aminergic metabolites in cerebrospinal fluid of humans previously exposed to MDMA: preliminary observations. Ann N Y Acad Sci 1990, 600:699–710. DOI: 10.1111/j.1749-6632.1990.tb16919.x
    • (1990) Ann N Y Acad Sci , vol.600 , pp. 699-710
    • Ricaurte, G.1    Finnegan, K.2    Irwin, I.3    Langston, J.4
  • 73
    • 0024558968 scopus 로고
    • Neuroendocrineand mood responses to intravenous L-tryptophan in 3,4-methylenedioxymethamphetamine (MDMA) users
    • PID: 2562914, COI: 1:CAS:528:DyaL1MXhtVyjtr4%3D
    • Price L, Ricaurte G, Krystal J, Heninger G: Neuroendocrineand mood responses to intravenous L-tryptophan in 3,4-methylenedioxymethamphetamine (MDMA) users. Arch Gen Psychiatry 1989, 46:20–22.
    • (1989) Arch Gen Psychiatry , vol.46 , pp. 20-22
    • Price, L.1    Ricaurte, G.2    Krystal, J.3    Heninger, G.4
  • 74
    • 0035140822 scopus 로고    scopus 로고
    • Cognitive performance and serotonergic function in users of Ecstasy
    • PID: 11205419, COI: 1:CAS:528:DC%2BD3MXhtlGitbg%3D
    • Verkes R, Gijsman H, Pieters M, et al.: Cognitive performance and serotonergic function in users of Ecstasy. Psychopharmacology 2001, 153:196–202. DOI: 10.1007/s002130000563
    • (2001) Psychopharmacology , vol.153 , pp. 196-202
    • Verkes, R.1    Gijsman, H.2    Pieters, M.3
  • 75
    • 0032985047 scopus 로고    scopus 로고
    • Reduced in vivo binding to the serotonin transporter in the cerebral cortex of MDMA (Ecstasy) users
    • PID: 10621770, COI: 1:STN:280:DC%2BD3c%2FoslKmsg%3D%3D, this study, 10 long-term Ecstasy users and 10 non-Ecstasy using but substance using controls were administered a serotonin transporter ligand before undergoing neuroimaging with single photon emission computed tomography (SPECT). Diminished binding to cortical serotonin transporters was found long-term Ecstasy users compared with controls that used substances other than Ecstasy
    • Semple D, Ebmeier K, Glabus M, et al.: Reduced in vivo binding to the serotonin transporter in the cerebral cortex of MDMA (Ecstasy) users. Br J Psychiatry 1999, 175:63–69. In this study, 10 long-term Ecstasy users and 10 non-Ecstasy using but substance using controls were administered a serotonin transporter ligand before undergoing neuroimaging with single photon emission computed tomography (SPECT). Diminished binding to cortical serotonin transporters was found in long-term Ecstasy users compared with controls that used substances other than Ecstasy.
    • (1999) Br J Psychiatry , vol.175 , pp. 63-69
    • Semple, D.1    Ebmeier, K.2    Glabus, M.3
  • 76
    • 0032797403 scopus 로고    scopus 로고
    • Ecstasy-long-term effects on the human central nervous system revealed by positron emission tomography
    • PID: 10627804, COI: 1:STN:280:DC%2BD3c%2Fptlaktg%3D%3D, This neuroimaging study used positron emission tomography (PET) and 2-[18F]-fluoro-2-deoxy-d-glucose to examine glucose metabolism, an indicator of neuronal activity, seven Ecstasy users who had not used the substance for 2 to 16 months and seven non-substance using controls. Decreased glucose metabolism the neurons of the hippocampus, amygdala, and cingulate was seen the abstinent Ecstasy users compared with the non-substance using controls
    • Obrocki J, Buchert R, Vaterlein O, et al.: Ecstasy-long-term effects on the human central nervous system revealed by positron emission tomography. Br J Psychiatry 1999, 175:186–188. This neuroimaging study used positron emission tomography (PET) and 2-[18F]-fluoro-2-deoxy-d-glucose to examine glucose metabolism, an indicator of neuronal activity, in seven Ecstasy users who had not used the substance for 2 to 16 months and seven non-substance using controls. Decreased glucose metabolism in the neurons of the hippocampus, amygdala, and cingulate was seen in the abstinent Ecstasy users compared with the non-substance using controls. DOI: 10.1192/bjp.175.2.186
    • (1999) Br J Psychiatry , vol.175 , pp. 186-188
    • Obrocki, J.1    Buchert, R.2    Vaterlein, O.3
  • 77
    • 0034913606 scopus 로고    scopus 로고
    • Long-term effects of Ecstasy abuse on the human brain studied by FDG PET
    • PID: 11473208, COI: 1:CAS:528:DC%2BD3MXmsVymsbs%3D, this study using PET, 93 Ecstasy users who had taken approximately 483 Ecstasy tablets for approximately 20 years (last use 6.5 months prior to the study) demonstrated decreased FDG uptake the striatum, cingulate, amygdala, cortex, and hippocampus, bilaterally when compared with 27 non-substance using controls. Greater reductions 2-[18F]-fluoro-2-deoxy-d-glucose uptake were seen those began using Ecstasy before the age of 18
    • Buchert R, Obrocki J, Thomasius R, et al.: Long-term effects of Ecstasy abuse on the human brain studied by FDG PET. Nucl Med Commun 2001, 22:889–897. In this study using PET, 93 Ecstasy users who had taken approximately 483 Ecstasy tablets for approximately 20 years (last use 6.5 months prior to the study) demonstrated decreased FDG uptake in the striatum, cingulate, amygdala, cortex, and hippocampus, bilaterally when compared with 27 non-substance using controls. Greater reductions in 2-[18F]-fluoro-2-deoxy-d-glucose uptake were seen in those began using Ecstasy before the age of 18. DOI: 10.1097/00006231-200108000-00007
    • (2001) Nucl Med Commun , vol.22 , pp. 889-897
    • Buchert, R.1    Obrocki, J.2    Thomasius, R.3
  • 78
    • 0033921324 scopus 로고    scopus 로고
    • Is MDMA neurotoxic in humans? An overview of evidence and of methodological problems in research
    • Curren H: Is MDMA neurotoxic in humans? An overview of evidence and of methodological problems in research. Neuropsychobiology 2000, 42:34–41. DOI: 10.1159/000026668
    • (2000) Neuropsychobiology , vol.42 , pp. 34-41
    • Curren, H.1
  • 79
    • 0034328019 scopus 로고    scopus 로고
    • Chemical analysis of Ecstasy pills
    • PID: 11056589, COI: 1:STN:280:DC%2BD3crgslWlsw%3D%3D, this study 107 Ecstasy tablets were examined for their content by GCMS. MDMA or its analogues, MDEA and MDA, were found 67 tablets although 31 tablets contained no MDMA, but other identifiable substances including dextromethorphan, caffeine, ephedrine, pseudoephedrine, and salicylates. Nine tablets contained no identifiable drug at all
    • Baggott M, Heifets B, Jones R, et al.: Chemical analysis of Ecstasy pills. JAMA 2000, 284:2190. In this study 107 Ecstasy tablets were examined for their content by GCMS. MDMA or its analogues, MDEA and MDA, were found in 67 tablets although 31 tablets contained no MDMA, but other identifiable substances including dextromethorphan, caffeine, ephedrine, pseudoephedrine, and salicylates. Nine tablets contained no identifiable drug at all. DOI: 10.1001/jama.284.17.2190
    • (2000) JAMA , vol.284 , pp. 2190
    • Baggott, M.1    Heifets, B.2    Jones, R.3
  • 80
    • 0032914385 scopus 로고    scopus 로고
    • Analysis of illicit Ecstasy tablets: implications for clinical management in the accident and emergency departments
    • PID: 10353046, COI: 1:STN:280:DyaK1M3otFeisA%3D%3D, Twenty-five Ecstasy tablets were analyzed for content by gas chromatography. Of the 25 tablets, 12 tablets contained MDMA, four tablets contained MDEA, and the other 9 contained no MDMA, but instead contained varying amounts of caffeine, amphetamine, ephedrine, ketamine, and paracetamol
    • Sherlock K, Wolff K, Hay A, Conner M: Analysis of illicit Ecstasy tablets: implications for clinical management in the accident and emergency departments. J Accid Emerg Med 1999, 16:194–197. Twenty-five Ecstasy tablets were analyzed for content by gas chromatography. Of the 25 tablets, 12 tablets contained MDMA, four tablets contained MDEA, and the other 9 contained no MDMA, but instead contained varying amounts of caffeine, amphetamine, ephedrine, ketamine, and paracetamol.
    • (1999) J Accid Emerg Med , vol.16 , pp. 194-197
    • Sherlock, K.1    Wolff, K.2    Hay, A.3    Conner, M.4


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