An active-site model of prostaglandin H synthase: An iron "twin-coronet" porphyrin with an aryloxyl radical overhang and its catalytic oxygenation of 1,4-diene

Angewandte Chemie - International Edition

Volumn 42, Issue 24, 2003, Pages 2744-2747

  Matsui, Eiki ^a   Naruta, Yoshinori ^a   Tani, Fumito ^a   Shimazaki, Yuichi ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Enzyme models; Iron; Porphyrinoids; Radical ions; Redox chemistry

Indexed keywords

ALCOHOLS; CATALYSIS; ENZYMES; OXIDATION; OXYGEN;

OXYGENATION;

PORPHYRINS;

ALKADIENE; IRON DERIVATIVE; PORPHYRIN DERIVATIVE; PROSTAGLANDIN SYNTHASE; RADICAL;

ARTICLE; CATALYSIS; ENZYME ACTIVE SITE; OXYGENATION; STEREOCHEMISTRY;

ALKENES; BINDING SITES; CATALYSIS; ELECTRON SPIN RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; OXYGEN; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROTEIN CONFORMATION;

EID: 0038391434     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200250431     Document Type: Article

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