Brazilian HTLV type 2a strains from intravenous drug users (IDUs) appear to have originated from two sources: Brazilian Amerindians and European/North American IDUs

AIDS Research and Human Retroviruses

Volumn 19, Issue 6, 2003, Pages 519-523

  Alcantara, Luiz C J ^a,b   Shindo, Nice ^a,b,c   Van Dooren, Sonia ^d   Salemi, Marco ^d   Costa, Maria C R ^e   Kashima, Simone ^e   Covas, Dimas T ^e   Vandamme, Anne Mieke ^d   Galvão Castro, Bernardo ^a,b  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b ESCOLA BAHIANA DE MEDICINA E SAÚDE PÚBLICA   (Brazil)

^c UNIVERSITY OF WASHINGTON   (United States)

^d REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^e Regional Blood Center of Ribeirão Preto   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN PX; TAX PROTEIN; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN;

ARTICLE; BLOOD DONOR; CONTROLLED STUDY; DISEASE ASSOCIATION; GENE ISOLATION; HUMAN; HUMAN T CELL LEUKEMIA VIRUS 2; HUMAN T CELL LEUKEMIA VIRUS INFECTION; INTRAVENOUS DRUG ABUSE; LONG TERMINAL REPEAT; MAJOR CLINICAL STUDY; NUCLEOTIDE SEQUENCE; PHYLOGENY; PRIORITY JOURNAL; PROMOTER REGION; RACE DIFFERENCE; SEQUENCE ANALYSIS; STRAIN DIFFERENCE; UNINDEXED SEQUENCE; URBAN AREA; VIRUS ISOLATION;

ADULT; BRAZIL; EUROPE; FEMALE; GENE PRODUCTS, ENV; HTLV-II INFECTIONS; HUMAN T-LYMPHOTROPIC VIRUS 2; HUMANS; INDIANS, SOUTH AMERICAN; MALE; MOLECULAR SEQUENCE DATA; NORTH AMERICA; PHYLOGENY; RETROVIRIDAE PROTEINS, ONCOGENIC; SEQUENCE ANALYSIS, DNA; SUBSTANCE ABUSE, INTRAVENOUS; TERMINAL REPEAT SEQUENCES;

EID: 0038391040     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/088922203766774577     Document Type: Article

References (15)

1. Andrade TM, Dourado I, and Galvao-Castro B: Associations among HTLV-I, HTLV-II, and HIV in injecting drug users in Salvador, Brazil. J AIDS Hum Retrovirol 1998;18:186-187.
2. Shindo N, Alcantara LCJ, Van Dooren S, et al.: Human retroviruses (HIV and HTLV) in Brazilian Indians: Seroepidemiological study and molecular epidemiology of HTLV-II isolates. AIDS Res Hum Retroviruses 2002;18:71-77.
3. Biggar RJ, Taylor ME, Neel JV, et al.: Genetic variants of human T-lymphotrophic virus type II in American Indian groups. Virology 1996;216:165-173.
4. Eiraku N, Novoa P, da Costa Ferreira M, et al.: Identification and characterization of a new and distinct molecular subtype of human T-cell lymphotropic virus type 2. J Virol 1996;70:1481-1492.
5. Ishak R, Harrington WJ Jr, Azevedo VN, et al.: Identification of human T cell lymphotropic virus type Ha infection in the Kayapo, an indigenous population of Brazil. AIDS Res Hum Retroviruses 1995;11:813-821.
6. Lewis MJ, Novoa P, Ishak R, et al.: Isolation, cloning, and complete nucleotide sequence of a phenotypically distinct Brazilian isolate of human T-lymphotropic virus type II (HTLV-II). Virology 2000;271:142-154.
7. Shimotohno K, Takahashi Y, Shimizu N, et al.: Complete nucleotide sequence of an infectious clone of human T-cell leukemia virus type II: An open reading frame for the protease gene. Proc Natl Acad Sci USA 1985;82:3101-3105.
8. Lee H, Idler KB, Swanson P, et al.: Complete nucleotide sequence of HTLV-II isolate NRA: Comparison of envelope sequence variation of HTLV-II isolates from U.S. blood donors and U.S. and Italian i.v. drug users. Virology 1993;196:57-69.
9. Gomes I, Melo A, Proietti FA, et al.: Human T lymphotropic virus type I (HTLV-I) infection in neurological patients in Salvador, Bahia, Brazil. J Neurol Sci 1999;165:84-89.
10. Switzer WM, Pieniazek D, Swanson P, et al.: Phylogenetic relationship and geographic distribution of multiple human T-cell lymphotropic virus type II subtypes. J Virol 1995;69:621-632.
11. Xia X: DAMBE: Data Analysis in Molecular Biology and Evolution. Department of Ecology and Biodiversity, University of Hong Kong, 2000.
12. Nicholas KB, Nicholas HBJ, and Deerfield DW: GeneDoc: Analysis and visualization of genetic variation; 1997; EMBNEW. NEWS 4.
13. Felsenstein J: PHYLIP (Phylogeny Inference Package), version 3.572 [distributed by the author]. Department of Genetics, University of Washington, Seattle, Washington, 1989.
14. Miura T, Yamashita M, Zaninovic V, et al.: Molecular phylogeny of human T-cell leukemia virus type I and II of Amerindians in Colombia and Chile. J Mol Evol 1997;44 (Suppl 1):S76-S82.
15. Switzer WM, Black FL, Pieniazek D, Biggar RJ, Lal RB, and Heneine W: Endemicity and phylogeny of the human T cell lymphotropic virus type II subtype A from the Kayapo Indians of Brazil: Evidence for limited regional dissemination. AIDS Res Hum Retroviruses 1996;12:635-640.