Cardiovascular and medical ramifications of treatment of subclinical hypothyroidism

Current Atherosclerosis Reports

Volumn 5, Issue 1, 2003, Pages 73-77

  Glueck, Charles J ^a   Streicher, Patricia ^a  

^a JEWISH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRIC ACID DERIVATIVE; GEMFIBROZIL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LEVOTHYROXINE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; THYROTROPIN; THYROXINE;

AGE DISTRIBUTION; CARDIOVASCULAR FUNCTION; CHOLESTEROL BLOOD LEVEL; DISEASE SEVERITY; FAMILY HISTORY; HEART FUNCTION; HUMAN; HYPERLIPIDEMIA; HYPOTHYROIDISM; MEDICAL DOCUMENTATION; MYOPATHY; PATIENT CARE; PREGNANCY; PSYCHOPATHY; REVIEW; SEX RATIO; SYMPTOMATOLOGY; THYROTROPIN BLOOD LEVEL; ADULT; CARDIOVASCULAR DISEASE; CHEMICALLY INDUCED DISORDER; FEMALE; MALE; MUSCLE DISEASE;

ADULT; CARDIOVASCULAR DISEASES; FEMALE; HUMANS; HYPOTHYROIDISM; MALE; MUSCULAR DISEASES; PREGNANCY; THYROXINE;

EID: 0038387254     PISSN: 15233804     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11883-003-0071-5     Document Type: Review

References (25)

1. Chu J, Crapo L: The treatment of subclinical hypothyroidism is seldom necessary. J Clin Endocrinol Metab 2001, 86:4591-4599.
2. Hollowell J, Staehling N, Flanders W, et al.: Serum TSH, T 4, and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III). J Clin Endocrinol Metab 2002, 87:489-499.
3. Huber G, Staub J, Meier C, et al.: Prospective study of the spontaneous course of subclinical hypothyroidism: prognostic value of thyrotropin, thyroid reserve, and thyroid antibodies. J Clin Endocrinol Metab 2002, 87:3221-3226.
4. McDermott M, Ridgeway E: Subclinical hypothyroidism is milk thyroid failure and should be treated. J Clin Endocrinol Metab 2001, 86:4585-4590.
5. Pirich C, Mullner M, Sinzinger H: Prevalence and relevance of thyroid dysfuntion in 1922 cholesterol screening participants. J Clin Epidemiol 2000, 53:623-629.
6. Hak AE, Pols HA, Visser TJ, et al.: Subclinical hypothyroidism is an independent risk factor for atherosclerosis and myocardial infarction in elderly women. Ann Intern Med 2000, 132:270-278.
7. Cooper DS, Halpern R, Wood LC, et al.: L-thyroxine therapy in subclinical hypothyroidism. A double-blind, placebo-controlled trial. Ann Intern Med 1984, 101:18-24.
8. Nystrom E, Caidahl K, Fager G, et al.: A double-blind crossover 12-month study of L-thyroxine treatment of women with "subclinical" hypothryroidism. Clin Endocrinol 1988, 29:63-75.
9. Jaeschke R, Guyatt G, Gertein H, et al.: Does treatment with L-thyroxine influence health status in middle-aged and older adults with subclinical hypothyroidism? Gen Intern Med 1996, 11:744-749.
10. Monzani F, Bello VD, Caraccio C, et al.: Effect of levothyroxine on cardiac function and structure in subclinical hypothyroidism: a double-blind, placebo-controlled study. J Clin Endocrinol Metab 2001, 86:1110-1115.
11. Meier C, Staub JJ, Roth CB, et al.: TSH-controlled L-thyroxine therapy reduces cholesterol levels and clinical symptoms in subclinical hypothryroidism: a double blind, placebo-controlled trial (Basel Thyroid Study). J Clin Endocrinol Metab 2001, 86:4860-4866.
12. Kong W, Sheikh M, Lumb P, et al.: A 6-month randomized trial of thyroxine treatment in women with mild subclinical hypothroidism. Am J Med 2002, 112:422-423.
13. Caraccio N, Ferrannini E, Monzani F: Lipoprotein profile in subclinical hypothyroidism: response to levothyroxine replacement, a randomized placebo-controlled study. J Clin Endocrinol Metab 2002, 87:1533-1538.
14. Evered DC, Ormston BJ, Smith PA, et al.: Grades of hypothyroidism. BMJ 1973, 1:657-662.
15. Vanderpump MP, Tunbridge WM, French JM, et al.: The development of ischemic heart disease in relation to autoimmune thyroid disease in a 20-year follow-up study of an English community. Thyroid 1996, 6:155-160.
16. Ladenson P, Wilson M, Gardin J, et al.: Relationship of subclinical hypothyroidism to cardiovascular risk factors and disease in an elderly population. Thyroid 1994, 4:518.
17. Lang J, Wang F, Glueck C: Myopathy associated with lipid lowering therapy in patients with previously undiagnosed or undertreated hypothyroidism. Clin Chim Acta 1996, 254:85-92.
18. Glueck CJ, Lang JE, Tracy T, et al.: The common finding of covert hypothyroidism at initial clinical evalution for hyperlipoproteinemia. Clin Chim Acta 1991, 201:113-122.
19. Arem R, Escalante D: Subclinical hypothyroidism: epidemiology, diagnosis, and significance. Adv Intern Med 1996, 41:213-250.
20. Hussein WI, Green R, Jacobsen, et al.: Normalization of hyperhomocysteinemia with L-thyroxine in hypothyroidism. Ann Intern Med 1999, 131:348-351.
21. Catargi B, Parrot-Roulaud F, Cochet C, et al.: Homocysteine, hypothyroidism, and effect of thyroid hormone replacement. Thyroid 1999, 9:1163-1166.
22. Abalovich M, Gutierrez S, Alcaraz G, et al.: Overt and subclinical hypothyroidism complicating pregnancy. Thyroid 2002, 12:63-68.
23. Canaris GJ, Manowitz NR, Mayor G, et al.: The Colorado thyroid disease prevalence study. Arch Intern Med 2000, 160:526-534.
24. DeWhaley P: Do abnormal thyroid stimulating hormone level values result in treatment changes? A study of patients on thyroxine in one general practice. Br J Gen Pract 1995, 45:93-95.
25. Vanderpump MP, Ahlquist JA, Franklyn JA, et al.: Consensus statement for good practice and audit measures in the management of hypothyroidism and hyperthyroidism. The Research Unit of the Royal College of Physicians of London, the Endocrinology and Diabetes Committee of the Royal College of Physicians of London, and the Society for Endocrinology. BMJ 1996, 313:539-544.