Persistent anticonvulsant hypersensitivity syndrome responding to ciclosporin

Clinical and Experimental Dermatology

Volumn 28, Issue 4, 2003, Pages 364-365

  Harman, K E ^a,b   Morris, S D ^a   Higgins, E M ^a  

^a KING S COLLEGE HOSPITAL   (United Kingdom)

^b LEICESTER ROYAL INFIRMARY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; CLOBETASOL PROPIONATE; CYCLOSPORIN; LAMOTRIGINE; PHENYTOIN; PREDNISOLONE; STEROID;

ADULT; ANTICONVULSANT HYPERSENSITIVITY SYNDROME; ANTICONVULSANT THERAPY; ARTICLE; CASE REPORT; CLINICAL FEATURE; CORTICOSTEROID THERAPY; DRUG HYPERSENSITIVITY; DRUG WITHDRAWAL; FEMALE; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; PRIORITY JOURNAL; SKIN BIOPSY; TREATMENT OUTCOME;

ADULT; ANTICONVULSANTS; BIOPSY; CYCLOSPORINE; DERMATOLOGIC AGENTS; DRUG ERUPTIONS; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; INTERLEUKIN-5; PHENYTOIN; PRURITUS; TRIAZINES;

EID: 0038383860     PISSN: 03076938     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2230.2003.01267.x     Document Type: Article

References (8)

1. Silverman AK, Fairley J, Wong RC. Cutaneous and immunologic reactions to phenytoin. J Am Acad Dermatol 1988; 18: 721-41.
2. Bocquet H, Bagot M, Roujeau J-C. Drug-induced pseudolymphoma and drug hypersensitivity syndrome (drug rash with eosinophilia and systemic symptoms: DRESS). Sem Cut Med Surg 1996; 15: 250-7.
3. Mills RM. Severe hypersensitivity reactions associated with allopurinol. JAMA 1971; 216: 799-802.
4. Tomsick RS. The phenytoin syndrome. Cutis 1983; 32: 535-41.
5. Harris DWS, Ostlere L, Buckley C, Whittaker S, Sweny P, Rustin MHA. Phenytoin-induced pseudolymphoma. A report of a case and review of the literature. Br J Dermatol 1992; 127: 403-6.
6. Callot V, Roujeau J-C, Bagot M et al. Drug-induced pseudolymphoma and hypersensitivity syndrome. Two different clinical entities. Arch Dermatol 1996; 132: 1315-21.
7. Choquet-Kastylevsky G, Intrator L, Chenal C, Bocquet H, Revuz J, Roujeau J-C. Increased levels of interleukin-5 are associated with the generaltion of eosinophilia in drug-induced hypersensitivity syndrome. Br J Dermatol 1998; 139: 1026-32.
8. Nakata A, Kaminuma O, Mori A et al. Evidence that cyclosporin A and dexamethosone inhibit allergic airway eosinophilic inflammation via suppression of interleukin-5 synthesis by T-cells. Br J Pharmacol 1998; 124: 1425-32.