메뉴 건너뛰기




Volumn 23, Issue 13, 2003, Pages 4522-4531

Loss of Sin3/Rpd3 histone deacetylase restores the DNA damage response in checkpoint-deficient strains of Saccharomyces cerevisiae

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE PROTEIN; DNA; GLUTATHIONE TRANSFERASE; HISTONE DEACETYLASE; HYBRID PROTEIN; PROTEIN MEC1; PROTEIN RAD9; PROTEIN RPD3; PROTEIN SIN3; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CHES1; TRANSCRIPTION FACTOR FOXN3; UNCLASSIFIED DRUG;

EID: 0038383032     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.23.13.4522-4531.2003     Document Type: Article
Times cited : (52)

References (54)
  • 1
    • 0021355377 scopus 로고
    • Relationship of actin and tubulin distribution to bud growth in wild-type and morphogenetic-mutant Saccharomyces cerevisiae
    • Adams, A. E., and J. R. Pringle. 1984. Relationship of actin and tubulin distribution to bud growth in wild-type and morphogenetic-mutant Saccharomyces cerevisiae. J. Cell Biol. 98:934-945.
    • (1984) J. Cell Biol. , vol.98 , pp. 934-945
    • Adams, A.E.1    Pringle, J.R.2
  • 2
    • 0032996507 scopus 로고    scopus 로고
    • The spindle checkpoint
    • Amon, A. 1999. The spindle checkpoint. Curr. Opin. Genet. Dev. 9:69-75.
    • (1999) Curr. Opin. Genet. Dev. , vol.9 , pp. 69-75
    • Amon, A.1
  • 3
    • 0034610367 scopus 로고    scopus 로고
    • Genomewide studies of histone deacetylase function in yeast
    • Bernstein, B. E., J. K. Tong, and S. L. Schreiher. 2000. Genomewide studies of histone deacetylase function in yeast. Proc. Natl. Acad. Sci. USA 97:13708-13713.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 13708-13713
    • Bernstein, B.E.1    Tong, J.K.2    Schreiher, S.L.3
  • 4
    • 0027407636 scopus 로고
    • Bipartite structure of an early meiotic upstream activation sequence from Saccharomyces cerevisiae
    • Bowdish, K. S., and A. P. Mitchell. 1993. Bipartite structure of an early meiotic upstream activation sequence from Saccharomyces cerevisiae. Mol. Cell. Biol. 13:2172-2181.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 2172-2181
    • Bowdish, K.S.1    Mitchell, A.P.2
  • 8
    • 0027300506 scopus 로고
    • Heat shock proteins: Molecular chaperones of protein biogenesis
    • Craig, E. A., B. D. Gambill, and R. J. Nelson. 1993. Heat shock proteins: molecular chaperones of protein biogenesis. Microbiol. Rev. 57:402-414.
    • (1993) Microbiol. Rev. , vol.57 , pp. 402-414
    • Craig, E.A.1    Gambill, B.D.2    Nelson, R.J.3
  • 9
    • 0034045040 scopus 로고    scopus 로고
    • Histone deacetylases, transcriptional control, and cancer
    • Cress, W. D., and E. Seto. 2000. Histone deacetylases, transcriptional control, and cancer. J. Cell. Physiol. 184:1-16.
    • (2000) J. Cell. Physiol. , vol.184 , pp. 1-16
    • Cress, W.D.1    Seto, E.2
  • 10
    • 0032530824 scopus 로고    scopus 로고
    • Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway
    • Desany, B. A., A. A. Alcasabas, J. B. Bachant, and S. J. Elledge. 1998. Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway. Genes Dev. 12:2956-2970.
    • (1998) Genes Dev. , vol.12 , pp. 2956-2970
    • Desany, B.A.1    Alcasabas, A.A.2    Bachant, J.B.3    Elledge, S.J.4
  • 11
    • 0033957793 scopus 로고    scopus 로고
    • The yeast Sgs1p helicase acts upstream of Rad53p in the DNA replication checkpoint and colocalizes with Rad53p in S-phase-specific foci
    • Frei, C., and S. M. Gasser. 2000. The yeast Sgs1p helicase acts upstream of Rad53p in the DNA replication checkpoint and colocalizes with Rad53p in S-phase-specific foci. Genes Dev. 14:81-96.
    • (2000) Genes Dev. , vol.14 , pp. 81-96
    • Frei, C.1    Gasser, S.M.2
  • 12
    • 0035989352 scopus 로고    scopus 로고
    • Overlapping roles of the spindle assembly and DNA damage checkpoints in the cell-cycle response to altered chromosomes in Saccharomyces cerevisiae
    • Garber, P. M., and J. Rine. 2002. Overlapping roles of the spindle assembly and DNA damage checkpoints in the cell-cycle response to altered chromosomes in Saccharomyces cerevisiae. Genetics 161:521-534.
    • (2002) Genetics , vol.161 , pp. 521-534
    • Garber, P.M.1    Rine, J.2
  • 13
    • 0034177830 scopus 로고    scopus 로고
    • The spindle checkpoint: Two transitions, two pathways
    • Gardner, R. D., and D. J. Burke. 2000. The spindle checkpoint: two transitions, two pathways. Trends Cell Biol. 10:154-158.
    • (2000) Trends Cell Biol. , vol.10 , pp. 154-158
    • Gardner, R.D.1    Burke, D.J.2
  • 14
    • 0024425887 scopus 로고
    • Checkpoints: Controls that ensure the order of cell cycle events
    • Hartwell, L. H., and T. A. Weinert. 1989. Checkpoints: controls that ensure the order of cell cycle events. Science 246:629-634.
    • (1989) Science , vol.246 , pp. 629-634
    • Hartwell, L.H.1    Weinert, T.A.2
  • 15
    • 0027525970 scopus 로고
    • Studies of the DNA binding properties of histone H4 amino terminus. Thermal denaturation studies reveal that acetylation markedly reduces the binding constant of the H4 "tail" to DNA
    • Hong, L., G. P. Schroth, H. R. Matthews, P. Yau, and E. M. Bradbury. 1993. Studies of the DNA binding properties of histone H4 amino terminus. Thermal denaturation studies reveal that acetylation markedly reduces the binding constant of the H4 "tail" to DNA. J. Biol. Chem. 268:305-314.
    • (1993) J. Biol. Chem. , vol.268 , pp. 305-314
    • Hong, L.1    Schroth, G.P.2    Matthews, H.R.3    Yau, P.4    Bradbury, E.M.5
  • 16
    • 0035577668 scopus 로고    scopus 로고
    • Histone H3 specific acetyltransferases are essential for cell cycle progression
    • Howe, L., D. Auston, P. Grant, S. John, R. G. Cook, J. L. Workman, and L. Pillus. 2001. Histone H3 specific acetyltransferases are essential for cell cycle progression. Genes Dev. 15:3144-3154.
    • (2001) Genes Dev. , vol.15 , pp. 3144-3154
    • Howe, L.1    Auston, D.2    Grant, P.3    John, S.4    Cook, R.G.5    Workman, J.L.6    Pillus, L.7
  • 18
    • 0035336971 scopus 로고    scopus 로고
    • Asf1 links Rad53 to control of chromatin assembly
    • Hu, F., A. A. Alcasahas, and S. J. Elledge. 2001. Asf1 links Rad53 to control of chromatin assembly. Genes Dev. 15:1061-1066.
    • (2001) Genes Dev. , vol.15 , pp. 1061-1066
    • Hu, F.1    Alcasahas, A.A.2    Elledge, S.J.3
  • 19
    • 0032488855 scopus 로고    scopus 로고
    • Eukaryotic transcription: An interlaced network of transcription factor and chromatin-modifying machines
    • Kadonaga, J. T. 1998. Eukaryotic transcription: an interlaced network of transcription factor and chromatin-modifying machines. Cell 92:307-313.
    • (1998) Cell , vol.92 , pp. 307-313
    • Kadonaga, J.T.1
  • 20
    • 0343924289 scopus 로고    scopus 로고
    • Repression by Ume6 involves recruitment of a complex containing Sin3 corepressor and Rpd3 histone deacetylase to target promoters
    • Kadosh, D., and K. Struhl. 1997. Repression by Ume6 involves recruitment of a complex containing Sin3 corepressor and Rpd3 histone deacetylase to target promoters. Cell 89:365-371.
    • (1997) Cell , vol.89 , pp. 365-371
    • Kadosh, D.1    Struhl, K.2
  • 21
    • 0030877160 scopus 로고    scopus 로고
    • A large protein complex containing the yeast Sin3p and Rpd3p transcriptional regulators
    • Kasten, M. M., S. Dorland, and D. J. Stillman. 1997. A large protein complex containing the yeast Sin3p and Rpd3p transcriptional regulators. Mol. Cell. Biol. 17:4852-4858.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 4852-4858
    • Kasten, M.M.1    Dorland, S.2    Stillman, D.J.3
  • 22
    • 0035955398 scopus 로고    scopus 로고
    • Recruitment of Mec1 and Ddc1 checkpoint proteins to double-strand breaks through distinct mechanisms
    • Kondo, T., T. Wakayama, T. Naiki, K. Matsumoto, and K. Sugimoto. 2001. Recruitment of Mec1 and Ddc1 checkpoint proteins to double-strand breaks through distinct mechanisms. Science 294:867-870.
    • (2001) Science , vol.294 , pp. 867-870
    • Kondo, T.1    Wakayama, T.2    Naiki, T.3    Matsumoto, K.4    Sugimoto, K.5
  • 23
    • 0032142918 scopus 로고    scopus 로고
    • Roles of histone acetyltransferases and deacetylases in gene regulation
    • Kuo, M. H., and C. D. Allis. 1998. Roles of histone acetyltransferases and deacetylases in gene regulation. Bioessays 20:615-626.
    • (1998) Bioessays , vol.20 , pp. 615-626
    • Kuo, M.H.1    Allis, C.D.2
  • 24
    • 0031820288 scopus 로고    scopus 로고
    • Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae
    • Longtine M. S., A. McKenzie III, D. J. Demarini, N. G. Shah, A. Wach, A. Brachat, P. Philippsen, and J. R. Pringle. 1998. Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae. Yeast 14:953-961.
    • (1998) Yeast , vol.14 , pp. 953-961
    • Longtine, M.S.1    McKenzie A. III2    Demarini, D.J.3    Shah, N.G.4    Wach, A.5    Brachat, A.6    Philippsen, P.7    Pringle, J.R.8
  • 26
    • 0036682516 scopus 로고    scopus 로고
    • EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Delta mutants
    • Maringele, L., and D. Lydall. 2002. EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Delta mutants. Genes Dev. 16:1919-1933.
    • (2002) Genes Dev. , vol.16 , pp. 1919-1933
    • Maringele, L.1    Lydall, D.2
  • 27
    • 0029123092 scopus 로고
    • Histone H4 and the maintenance of genome integrity
    • Megee, P. C., B. A. Morgan, and M. M. Smith. 1995. Histone H4 and the maintenance of genome integrity. Genes Dev. 9:1716-1727.
    • (1995) Genes Dev. , vol.9 , pp. 1716-1727
    • Megee, P.C.1    Morgan, B.A.2    Smith, M.M.3
  • 28
    • 0035498938 scopus 로고    scopus 로고
    • Two checkpoint complexes are independently recruited to sites of DNA damage in vivo
    • Melo, J. A., J. Cohen, and D. P. Toczyski. 2001. Two checkpoint complexes are independently recruited to sites of DNA damage in vivo. Genes Dev. 15:2809-2821.
    • (2001) Genes Dev. , vol.15 , pp. 2809-2821
    • Melo, J.A.1    Cohen, J.2    Toczyski, D.P.3
  • 29
    • 0037195281 scopus 로고    scopus 로고
    • DNA damage during mitosis in human cells delays the metaphase/anaphase transition via the spindle-assembly checkpoint
    • Mikhailov, A., R. W. Cole, and C. L. Rieder. 2002. DNA damage during mitosis in human cells delays the metaphase/anaphase transition via the spindle-assembly checkpoint. Curr. Biol. 12:1797-1806.
    • (2002) Curr. Biol. , vol.12 , pp. 1797-1806
    • Mikhailov, A.1    Cole, R.W.2    Rieder, C.L.3
  • 30
    • 0025880340 scopus 로고
    • The highly conserved N-terminal domains of histones H3 and H4 are required for normal cell cycle progression
    • Morgan, B. A., B. A. Mittman, and M. M. Smith. 1991. The highly conserved N-terminal domains of histones H3 and H4 are required for normal cell cycle progression. Mol. Cell. Biol. 11:4111-4120.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 4111-4120
    • Morgan, B.A.1    Mittman, B.A.2    Smith, M.M.3
  • 31
    • 0344431240 scopus 로고    scopus 로고
    • FR901228, a potent antitumor antibiotic, is a novel histone deacetylase inhibitor
    • Nakajima, H., Y. B. Kim, H. Terano, M. Yoshida, and S. Horinouchi. 1998. FR901228, a potent antitumor antibiotic, is a novel histone deacetylase inhibitor. Exp. Cell. Res. 241:126-133.
    • (1998) Exp. Cell. Res. , vol.241 , pp. 126-133
    • Nakajima, H.1    Kim, Y.B.2    Terano, H.3    Yoshida, M.4    Horinouchi, S.5
  • 32
    • 0032527776 scopus 로고    scopus 로고
    • Mec1p is essential for phosphorylation of the yeast DNA damage checkpoint protein Ddc1p, which physically interacts with Mec3p
    • Paciotti, V., G. Lucchini, P. Plevani, and M. P. Longhese. 1998. Mec1p is essential for phosphorylation of the yeast DNA damage checkpoint protein Ddc1p, which physically interacts with Mec3p. EMBO J. 17:4199-4209.
    • (1998) EMBO J. , vol.17 , pp. 4199-4209
    • Paciotti, V.1    Lucchini, G.2    Plevani, P.3    Longhese, M.P.4
  • 33
    • 0030912117 scopus 로고    scopus 로고
    • Reconstitution of a MEC1-independent checkpoint in yeast by expression of a novel human fork head cDNA
    • Pati, D., C. Keller, M. Groudine, and S. E. Plon. 1997. Reconstitution of a MEC1-independent checkpoint in yeast by expression of a novel human fork head cDNA. Mol. Cell. Biol. 17:3037-3046.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 3037-3046
    • Pati, D.1    Keller, C.2    Groudine, M.3    Plon, S.E.4
  • 35
    • 0032560117 scopus 로고    scopus 로고
    • Transcriptional repression by UME6 involves deacetylation of lysine 5 of histone H4 by RPD3
    • Rundlett, S. E., A. A. Carmen, N. Suka, B. M. Turner, and M. Grunstein. 1998. Transcriptional repression by UME6 involves deacetylation of lysine 5 of histone H4 by RPD3. Nature 392:831-835.
    • (1998) Nature , vol.392 , pp. 831-835
    • Rundlett, S.E.1    Carmen, A.A.2    Suka, N.3    Turner, B.M.4    Grunstein, M.5
  • 36
    • 0033520944 scopus 로고    scopus 로고
    • Histone deacetylase inhibition selectively alters the activity and expression of cell cycle proteins leading to specific chromatin acetylation and antiproliferative effects
    • Sambucetti, L. C., D. D. Fischer, S. Zabludoff, P. O. Kwon, H. Chamberlin, N. Trogani, H. Xu, and D. Cohen. 1999. Histone deacetylase inhibition selectively alters the activity and expression of cell cycle proteins leading to specific chromatin acetylation and antiproliferative effects. J. Biol. Chem. 274:34940-34947.
    • (1999) J. Biol. Chem. , vol.274 , pp. 34940-34947
    • Sambucetti, L.C.1    Fischer, D.D.2    Zabludoff, S.3    Kwon, P.O.4    Chamberlin, H.5    Trogani, N.6    Xu, H.7    Cohen, D.8
  • 37
    • 0030593033 scopus 로고    scopus 로고
    • Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways
    • Sanchez, Y., B. A. Desany, W. J. Jones, Q. Liu, B. Wang, and S. J. Elledge. 1996. Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways. Science 271:357-360.
    • (1996) Science , vol.271 , pp. 357-360
    • Sanchez, Y.1    Desany, B.A.2    Jones, W.J.3    Liu, Q.4    Wang, B.5    Elledge, S.J.6
  • 38
    • 0024522727 scopus 로고
    • Cloning and sequence analysis of the Saccharomyces cerevisiae RAD9 gene and further evidence that its product is required for cell cycle arrest induced by DNA damage
    • Schiestl, R. H., P. Reynolds, S. Prakash, and L. Prakash. 1989. Cloning and sequence analysis of the Saccharomyces cerevisiae RAD9 gene and further evidence that its product is required for cell cycle arrest induced by DNA damage. Mol. Cell. Biol. 9:1882-1896.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 1882-1896
    • Schiestl, R.H.1    Reynolds, P.2    Prakash, S.3    Prakash, L.4
  • 39
    • 0030678627 scopus 로고    scopus 로고
    • Role of the retinoblastoma protein in the pathogenesis of human cancer
    • Sellers, W. R., and W. G. Kaelin, Jr. 1997. Role of the retinoblastoma protein in the pathogenesis of human cancer. J. Clin. Oncol. 15:3301-3312.
    • (1997) J. Clin. Oncol. , vol.15 , pp. 3301-3312
    • Sellers, W.R.1    Kaelin W.G., Jr.2
  • 40
    • 0346034996 scopus 로고    scopus 로고
    • A new role for the transcriptional corepressor SIN3; Regulation of centromeres
    • Silverstein, R. A., W. Richardson, H. Levin, R. Allshire, and K. Ekwall. 2003. A new role for the transcriptional corepressor SIN3; regulation of centromeres. Curr. Biol. 13:68-72.
    • (2003) Curr. Biol. , vol.13 , pp. 68-72
    • Silverstein, R.A.1    Richardson, W.2    Levin, H.3    Allshire, R.4    Ekwall, K.5
  • 41
    • 0028297156 scopus 로고
    • Epistasis analysis of suppressor mutations that allow HO expression in the absence of the yeast SW15 transcriptional activator
    • Stillman, D. J., S. Dorland, and Y. Yu. 1994. Epistasis analysis of suppressor mutations that allow HO expression in the absence of the yeast SW15 transcriptional activator. Genetics 136:781-788.
    • (1994) Genetics , vol.136 , pp. 781-788
    • Stillman, D.J.1    Dorland, S.2    Yu, Y.3
  • 42
    • 0024834986 scopus 로고
    • Identification of negative regulatory genes that govern the expression of early meiotic genes in yeast
    • Strich, R., M. R. Slater, and R. E. Esposito. 1989. Identification of negative regulatory genes that govern the expression of early meiotic genes in yeast. Proc. Natl. Acad. Sci. USA 86:10018-10022.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 10018-10022
    • Strich, R.1    Slater, M.R.2    Esposito, R.E.3
  • 43
    • 0032030770 scopus 로고    scopus 로고
    • Histone acetylation and transcriptional regulatory mechanisms
    • Struhl, K. 1998. Histone acetylation and transcriptional regulatory mechanisms. Genes Dev. 12:599-606.
    • (1998) Genes Dev. , vol.12 , pp. 599-606
    • Struhl, K.1
  • 44
    • 0032126535 scopus 로고    scopus 로고
    • A mutation in NPS1/STH1, an essential gene encoding a component of a novel chromatin-remodeling complex RSC, alters the chromatin structure of Saccharomyces cerevisiae centromeres
    • Tsuchiya, E., T. Hosotani, and T. Miyakawa. 1998. A mutation in NPS1/STH1, an essential gene encoding a component of a novel chromatin-remodeling complex RSC, alters the chromatin structure of Saccharomyces cerevisiae centromeres. Nucleic Acids Res. 26:3286-3292.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 3286-3292
    • Tsuchiya, E.1    Hosotani, T.2    Miyakawa, T.3
  • 45
    • 0031009397 scopus 로고    scopus 로고
    • Chromatin remodeling and transcription
    • Tsukiyama, T., and C. Wu. 1997. Chromatin remodeling and transcription. Curr. Opin. Genet. Dev. 7:182-191.
    • (1997) Curr. Opin. Genet. Dev. , vol.7 , pp. 182-191
    • Tsukiyama, T.1    Wu, C.2
  • 47
    • 0026060619 scopus 로고
    • RPD3 encodes a second factor required to achieve maximum positive and negative transcriptional states in Saccharomyces cerevisiae
    • Vidal, M., and R. F. Gaber. 1991. RPD3 encodes a second factor required to achieve maximum positive and negative transcriptional states in Saccharomyces cerevisiae. Mol. Cell. Biol. 11:6317-5327.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 6317-6327
    • Vidal, M.1    Gaber, R.F.2
  • 48
    • 0026046959 scopus 로고
    • RPD1 (S1N3/UME4) is required for maximal activation and repression of diverse yeast genes
    • Vidal, M., R. Strich, R. E. Esposito, and R. F. Gaber. 1991. RPD1 (S1N3/UME4) is required for maximal activation and repression of diverse yeast genes. Mol. Cell. Biol. 11:6306-6316.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 6306-6316
    • Vidal, M.1    Strich, R.2    Esposito, R.E.3    Gaber, R.F.4
  • 50
    • 0035063182 scopus 로고    scopus 로고
    • Transcriptional control at regulatory checkpoints by histone deacetylases: Molecular connections between cancer and chromatin
    • Wade, P. A. 2001. Transcriptional control at regulatory checkpoints by histone deacetylases: molecular connections between cancer and chromatin. Hum. Mol. Genet. 10:693-698.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 693-698
    • Wade, P.A.1
  • 51
    • 0028353634 scopus 로고
    • Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair
    • Weinert, T. A., G. L. Kiser, and L. H. Hartwell. 1994. Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair. Genes Dev. 8:652-665.
    • (1994) Genes Dev. , vol.8 , pp. 652-665
    • Weinert, T.A.1    Kiser, G.L.2    Hartwell, L.H.3
  • 52
    • 0032161269 scopus 로고    scopus 로고
    • A suppressor of two essential checkpoint genes identifies a novel protein that negatively affects dNTP pools
    • Zhao, X., E. G. Muller, and R. Rothstein. 1998. A suppressor of two essential checkpoint genes identifies a novel protein that negatively affects dNTP pools. Mol. Cell 2:329-340.
    • (1998) Mol. Cell , vol.2 , pp. 329-340
    • Zhao, X.1    Muller, E.G.2    Rothstein, R.3
  • 53
    • 0034707047 scopus 로고    scopus 로고
    • The DNA damage response: Putting checkpoints in perspective
    • Zhou, B. B., and S. J. Elledge. 2000. The DNA damage response: putting checkpoints in perspective. Nature 408:433-439.
    • (2000) Nature , vol.408 , pp. 433-439
    • Zhou, B.B.1    Elledge, S.J.2
  • 54
    • 0037080675 scopus 로고    scopus 로고
    • Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin
    • Zou, L., D. Cortez, and S. J. Elledge. 2002. Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin. Genes Dev 16:198-208.
    • (2002) Genes Dev. , vol.16 , pp. 198-208
    • Zou, L.1    Cortez, D.2    Elledge, S.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.