Majority of children aged 3 years and above can reliably inhale through the Clickhaler

Pediatric Pulmonology

Volumn 36, Issue 1, 2003, Pages 63-68

  Iqbal, Shaique M ^a   Ritson, Sue ^a   Buck, Helen ^b   Ellis, Sally ^b   Everard, Mark L ^a  

^a SHEFFIELD CHILDREN S HOSPITAL   (United Kingdom)

^b Innovata Biomed Ltd   (United Kingdom)

Author keywords

Dry powder inhaler; Inspiratory flow; Preschool children

Indexed keywords

ARTICLE; ASTHMA; CONTROLLED STUDY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PATIENT EDUCATION; POWDER INHALER; PRESCHOOL CHILD; PRIORITY JOURNAL; RESPIRATORY AIRFLOW;

ADMINISTRATION, INHALATION; AGE FACTORS; ANTI-ASTHMATIC AGENTS; ASTHMA; CASE-CONTROL STUDIES; EQUIPMENT SAFETY; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; NEBULIZERS AND VAPORIZERS; PATIENT COMPLIANCE; REFERENCE VALUES; REPRODUCIBILITY OF RESULTS; RESPIRATORY FUNCTION TESTS; RISK ASSESSMENT; SAMPLING STUDIES; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME;

EID: 0038382900     PISSN: 87556863     EISSN: None     Source Type: Journal    
DOI: 10.1002/ppul.10306     Document Type: Article

References (15)

1. British Thoracic Society. British Thoracic Society guidelines on asthma management 1995. Thorax 1997;52:1-21.
2. Agertoft L, Pedersen S. Importance of training for correct Turbuhaler use in pre-school children. Acta Paediatr (Scand) 1998;87:842-847.
3. National Institute for Clinical Excellence. Technology appraisal guidance-no. 10. Guidance on the use of inhaler systems (devices) in children under the age of 5 years with chronic asthma. London: National Institute for Clinical Excellence; 2000.
4. Pedersen S, Hanson OR, Fuglsang G. Influence of inspiratory flow rate upon the effect of a Turbuhaler. Arch Dis Child 1990;65:308-310.
5. Devadason SG, Everard ML, MacEarlan C, Roller C, Summers QA, Swift P, Borgstrom L, Le Souëf PN. Lung deposition from the Turbuhaler® in children with cystic fibrosis. Eur Respir J 1997;10:2023-2028.
6. Pedersen S. Inspiratory capacity through the Turbuhaler in various patient groups. J Aerosol Med 1994;7:55-58.
7. Everard ML, Devadason SG, Le Souëf PN. Flow early in the inspiratory manoeuvre affects the aerosol particle size distribution from a Turbuhaler. Respir Med 1997;91:624-628.
8. O'Callaghan C, Everard ML, Bush A, Hiller EJ, Ross-Russell R, O'Keefe P, Weller P. Salbutamol dry powder inhaler: double-blind efficacy and open acceptability studies. Pediatr Pulmonol 2002;33:189-193.
9. Adler LM, Anand C, Wright FGL, Barrett CF, McKeith D, Clark WIC, Maksimczyk P, Martin GDR, McKinnon C, Raffles AKM, Buck H. Efficacy and tolerability of beclomethasone dipropionate delivered by a novel multidose dry powder inhaler (Clickhaler®) versus a metered dose inhaler in children with asthma. Curr Ther Res Clin Exp 2001;62:758-769.
10. Chege JK, Chrystyn H. The relative bioavailability of salbutamol to the lung using urinary excretion following inhalation from a novel dry powder inhaler: the effect of inhalation rate and formulation. Respir Med 2000;94:51-56.
11. Newhouse MT, Nantel NP, Chambers CB, Pratt B, Parry-Billings M. Clickhaler (a novel dry powder inhaler) provides similar bronchodilation to pressurized metered-dose inhaler, even at low flow rates. Chest 1999;115:952-956.
12. Jones RD, Morice AH. Inspiratory flow rates through a novel dry powder inhaler (Clickhaler™) in pediatric asthmatic patients. Am J Respir Crit Care Med 1998;157:124.
13. Parry-Billings M, Birrell C, Oldham L, O'Callaghan C. Inspiratory flow rate through a dry powder inhaler (Clickhaler®) in children with asthma. Pediatr Pulmonol 2003;35:220-226.
14. Everard ML, Brennan V. Contrivance - a major cause for failure of aerosol therapy in childhood. Eur Respir J [Suppl] 2002;20:429.
15. Shim C. Spacer disuse Am J Crit Care Respir Med 2000;161:320.