Neutralizing anti-insulin-like growth factor receptor 1 antibodies inhibit receptor function and induce receptor degradation in tumor cells

Molecular Cancer Therapeutics

Volumn 1, Issue 14, 2002, Pages 1349-1353

  Hailey, Judith ^a   Maxwell, Eugene ^a   Koukouras, Kathy ^a   Bishop, W Robert ^a   Pachter, Jonathan A ^a   Wang, Yan ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGAR; MONOCLONAL ANTIBODY; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR;

ARTICLE; CELL CULTURE; CELL TRANSFORMATION; CHEMISTRY; DOSE RESPONSE; DOWN REGULATION; HUMAN; IC 50; IMMUNOLOGY; LYSOSOME; METABOLISM; PHOSPHORYLATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; SERODIAGNOSIS; SIGNAL TRANSDUCTION; TIME; WESTERN BLOTTING;

AGAR; ANTIBODIES, MONOCLONAL; BLOTTING, WESTERN; CELL TRANSFORMATION, NEOPLASTIC; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; INHIBITORY CONCENTRATION 50; INSULIN-LIKE GROWTH FACTOR I; LYSOSOMES; PHOSPHORYLATION; PRECIPITIN TESTS; RECEPTOR, IGF TYPE 1; SIGNAL TRANSDUCTION; TIME FACTORS; TUMOR CELLS, CULTURED;

EID: 0038380346     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: None     Document Type: Article

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